CRCGN015_MCF10A.TP53.M_24H:A04 Gene Set
Genes
53 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TBX2
|
T-box 2
|
4.2823
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.8154
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
3.56093
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
3.27838
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.12235
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
3.00503
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.96936
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.79314
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.61327
|
|
TLCD3A
|
TLC domain containing 3A
|
2.57459
|
|
FCHO1
|
FCH domain only 1
|
2.52297
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
2.51984
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.51604
|
|
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit
|
2.43875
|
|
GMPS
|
guanine monphosphate synthase
|
2.3278
|
|
ZNF124
|
zinc finger protein 124
|
2.29951
|
|
ZBTB5
|
zinc finger and BTB domain containing 5
|
2.26243
|
|
POGLUT2
|
protein O-glucosyltransferase 2
|
2.25358
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.24623
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.21461
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
2.12524
|
|
TIPRL
|
TOR signaling pathway regulator
|
2.11031
|
|
SREK1IP1
|
SREK1-interacting protein 1
|
2.07471
|
|
CHN1
|
chimerin 1
|
2.07277
|
|
DCTPP1
|
dCTP pyrophosphatase 1
|
2.05351
|
|
TBCCD1
|
TBCC domain containing 1
|
2.04735
|
|
HACL2
|
2-hydroxyacyl-CoA lyase 2
|
2.04155
|
|
ANKRD36C
|
ankyrin repeat domain 36C
|
2.02158
|
|
ZNF232
|
zinc finger protein 232
|
2.01226
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-4.75223
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-4.18435
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.80639
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.79548
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.51176
|
|
WASHC4
|
WASH complex subunit 4
|
-3.41683
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.27396
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.24646
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.68481
|
|
CD81
|
CD81 molecule
|
-2.62665
|
|
PTK2
|
protein tyrosine kinase 2
|
-2.56566
|
|
TP53RK
|
TP53 regulating kinase
|
-2.4803
|
|
MRPL42
|
mitochondrial ribosomal protein L42
|
-2.46795
|
|
ATP5F1E
|
ATP synthase F1 subunit epsilon
|
-2.46023
|
|
ISCU
|
iron-sulfur cluster assembly enzyme
|
-2.34095
|
|
MED13L
|
mediator complex subunit 13-like
|
-2.24879
|
|
MRPS33
|
mitochondrial ribosomal protein S33
|
-2.13592
|
|
CAPZA2
|
capping protein (actin filament) muscle Z-line, alpha 2
|
-2.12502
|
|
RPS27L
|
ribosomal protein S27-like
|
-2.11197
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-2.10815
|
|
QDPR
|
quinoid dihydropteridine reductase
|
-2.08574
|
|
CYP1A1
|
cytochrome P450, family 1, subfamily A, polypeptide 1
|
-2.04679
|
|
PCNP
|
PEST proteolytic signal containing nuclear protein
|
-2.03879
|
|
CEP43
|
centrosomal protein 43
|
-2.02336
|
