| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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188 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 5.65412 |
| HBB | hemoglobin, beta | 5.54462 |
| HBA1 | hemoglobin, alpha 1 | 4.9185 |
| TENT4A | terminal nucleotidyltransferase 4A | 4.83355 |
| AXIN1 | axin 1 | 4.13115 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.94291 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.84833 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.82402 |
| SNX11 | sorting nexin 11 | 3.63721 |
| AURKB | aurora kinase B | 3.47623 |
| RPL39L | ribosomal protein L39-like | 3.37489 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 3.31052 |
| TBXA2R | thromboxane A2 receptor | 3.28615 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.05606 |
| WASHC5 | WASH complex subunit 5 | 3.03177 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.84897 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.80703 |
| C4BPB | complement component 4 binding protein, beta | 2.74895 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 2.71477 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.62704 |
| MMP2 | matrix metallopeptidase 2 | 2.59986 |
| ASL | argininosuccinate lyase | 2.55319 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 2.52138 |
| MDFI | MyoD family inhibitor | 2.51866 |
| ELAC2 | elaC ribonuclease Z 2 | 2.50987 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.50542 |
| GSDMD | gasdermin D | 2.48917 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 2.48755 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 2.43718 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | 2.42089 |
| TK1 | thymidine kinase 1, soluble | 2.41551 |
| SLC12A9 | solute carrier family 12, member 9 | 2.40204 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 2.36025 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 2.35409 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.34825 |
| CSNK1G3 | casein kinase 1, gamma 3 | 2.34746 |
| CPA4 | carboxypeptidase A4 | 2.34583 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 | 2.34513 |
| TMEM259 | transmembrane protein 259 | 2.33148 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.30676 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.29594 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 2.2888 |
| PYDC1 | PYD (pyrin domain) containing 1 | 2.2824 |
| ZNF35 | zinc finger protein 35 | 2.27037 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 2.26649 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 2.26181 |
| KLF13 | Kruppel-like factor 13 | 2.2482 |
| RARG | retinoic acid receptor, gamma | 2.23493 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | 2.2321 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 2.22377 |
| DPH2 | DPH2 homolog (S. cerevisiae) | 2.21828 |
| SLC10A3 | solute carrier family 10, member 3 | 2.2084 |
| MEGF6 | multiple EGF-like-domains 6 | 2.20784 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 2.20264 |
| CEP72 | centrosomal protein 72kDa | 2.20173 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.19732 |
| RELN | reelin | 2.19466 |
| ISOC1 | isochorismatase domain containing 1 | 2.18491 |
| TRIB3 | tribbles pseudokinase 3 | 2.17813 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | 2.17084 |
| PPT2 | palmitoyl-protein thioesterase 2 | 2.16836 |
| C8A | complement component 8, alpha polypeptide | 2.16492 |
| ANKRD6 | ankyrin repeat domain 6 | 2.15427 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 | 2.14927 |
| C4BPA | complement component 4 binding protein, alpha | 2.14368 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.12921 |
| PRR15L | proline rich 15-like | 2.12661 |
| TMEM176B | transmembrane protein 176B | 2.12028 |
| SRGN | serglycin | 2.11934 |
| PRSS16 | protease, serine, 16 (thymus) | 2.11867 |
| CFHR2 | complement factor H-related 2 | 2.1137 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 | 2.10571 |
| LRRK1 | leucine-rich repeat kinase 1 | 2.10083 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 2.09143 |
| GRK5 | G protein-coupled receptor kinase 5 | 2.08969 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 | 2.08665 |
| HROB | homologous recombination factor with OB-fold | 2.08247 |
| CTIF | CBP80/20-dependent translation initiation factor | 2.08216 |
| APCS | amyloid P component, serum | 2.07754 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | 2.07569 |
| LY6E | lymphocyte antigen 6 complex, locus E | 2.05901 |
| MAT1A | methionine adenosyltransferase I, alpha | 2.05881 |
| FAT1 | FAT atypical cadherin 1 | 2.05248 |
| CACNA1B | calcium channel, voltage-dependent, N type, alpha 1B subunit | 2.04939 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.04314 |
| MEST | mesoderm specific transcript | 2.03374 |
| WDR44 | WD repeat domain 44 | 2.03042 |
| AGO2 | argonaute RISC catalytic component 2 | 2.02601 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 2.02349 |
| HYOU1 | hypoxia up-regulated 1 | 2.02207 |
| ZNF250 | zinc finger protein 250 | 2.01863 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | 2.01821 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.01523 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.01509 |
| RPN1 | ribophorin I | 2.01419 |
| KIF18B | kinesin family member 18B | 2.00554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UFM1 | ubiquitin-fold modifier 1 | -8.42073 |
| MRPS16 | mitochondrial ribosomal protein S16 | -5.84236 |
| CD81 | CD81 molecule | -4.91691 |
| CCDC86 | coiled-coil domain containing 86 | -4.87076 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -4.80369 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.18209 |
| COTL1 | coactosin-like F-actin binding protein 1 | -4.11629 |
| CD44 | CD44 molecule (Indian blood group) | -4.11353 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -4.08187 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -3.70628 |
| CDK4 | cyclin-dependent kinase 4 | -3.65577 |
| PIH1D1 | PIH1 domain containing 1 | -3.13983 |
| CD58 | CD58 molecule | -3.13677 |
| NVL | nuclear VCP-like | -3.08858 |
| UBL3 | ubiquitin-like 3 | -2.9496 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.9336 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -2.92666 |
| EXOSC8 | exosome component 8 | -2.89132 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.86855 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.86065 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -2.84132 |
| TMEM258 | transmembrane protein 258 | -2.77992 |
| TSPAN31 | tetraspanin 31 | -2.77379 |
| TSPAN3 | tetraspanin 3 | -2.66969 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -2.64715 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | -2.61955 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -2.60289 |
| LETMD1 | LETM1 domain containing 1 | -2.59249 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -2.52793 |
| RANGRF | RAN guanine nucleotide release factor | -2.50734 |
| RPS5 | ribosomal protein S5 | -2.50117 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -2.48953 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -2.45133 |
| MRPL23 | mitochondrial ribosomal protein L23 | -2.45056 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -2.45017 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -2.4432 |
| CDC20 | cell division cycle 20 | -2.44245 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -2.44137 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -2.41086 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -2.37798 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | -2.37726 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -2.36704 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -2.34444 |
| POMP | proteasome maturation protein | -2.32316 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -2.32195 |
| FOSL1 | FOS-like antigen 1 | -2.31561 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | -2.31488 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -2.31362 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G | -2.31355 |
| CHMP2A | charged multivesicular body protein 2A | -2.31196 |
| FAM114A2 | family with sequence similarity 114, member A2 | -2.31094 |
| RPLP2 | ribosomal protein, large, P2 | -2.30641 |
| CHI3L2 | chitinase 3-like 2 | -2.29643 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -2.29501 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | -2.26881 |
| TCTA | T-cell leukemia translocation altered | -2.264 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -2.26298 |
| RPN2 | ribophorin II | -2.2469 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | -2.22092 |
| MRPL57 | mitochondrial ribosomal protein L57 | -2.1783 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -2.17599 |
| ABITRAM | actin binding transcription modulator | -2.1745 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -2.1518 |
| TMEM14B | transmembrane protein 14B | -2.14787 |
| TMX2 | thioredoxin-related transmembrane protein 2 | -2.14013 |
| MLEC | malectin | -2.13755 |
| MPV17L-BMERB1 | MPV17L-BMERB1 readthrough | -2.13657 |
| ENO2 | enolase 2 (gamma, neuronal) | -2.1306 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | -2.1232 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.12267 |
| SSR4 | signal sequence receptor, delta | -2.12117 |
| DUSP14 | dual specificity phosphatase 14 | -2.11836 |
| GFUS | GDP-L-fucose synthase | -2.10648 |
| WASHC3 | WASH complex subunit 3 | -2.09371 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.08437 |
| TPT1 | tumor protein, translationally-controlled 1 | -2.08089 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.06477 |
| RPL4 | ribosomal protein L4 | -2.0592 |
| MSMO1 | methylsterol monooxygenase 1 | -2.0559 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -2.04684 |
| RPL19 | ribosomal protein L19 | -2.04171 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -2.03491 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -2.02554 |
| TMEM134 | transmembrane protein 134 | -2.02384 |
| RPL29 | ribosomal protein L29 | -2.0213 |
| LBHD1 | LBH domain containing 1 | -2.01523 |
| SCAF8 | SR-related CTD-associated factor 8 | -2.00858 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -2.0076 |
| TERF2 | telomeric repeat binding factor 2 | -2.00461 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) | -2.00288 |
| PRPF19 | pre-mRNA processing factor 19 | -2.00245 |
| ARF1 | ADP-ribosylation factor 1 | -2.00104 |
