CRCGN015_MCF10A.TP53.M_24H:A06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 4.48751
MAMLD1 mastermind-like domain containing 1 3.79891
CHMP6 charged multivesicular body protein 6 3.36406
ADRB2 adrenoceptor beta 2, surface 3.06486
EAPP E2F-associated phosphoprotein 2.84106
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.69369
RAI14 retinoic acid induced 14 2.66348
FCHO1 FCH domain only 1 2.59612
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.51318
CERK ceramide kinase 2.49796
GARRE1 granule associated Rac and RHOG effector 1 2.45244
GADD45A growth arrest and DNA-damage-inducible, alpha 2.42448
ELAC2 elaC ribonuclease Z 2 2.40536
HBA1 hemoglobin, alpha 1 2.20946
RPN1 ribophorin I 2.2064
CCNF cyclin F 2.16679
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.12509
MTA2 metastasis associated 1 family, member 2 2.0858
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.0729
RCL1 RNA terminal phosphate cyclase-like 1 2.03269
CCNA1 cyclin A1 2.00322

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -3.66724
OXA1L oxidase (cytochrome c) assembly 1-like -3.43149
NGRN neugrin, neurite outgrowth associated -2.84367
BASP1 brain abundant, membrane attached signal protein 1 -2.66727
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.36608
COTL1 coactosin-like F-actin binding protein 1 -2.35278
PSRC1 proline/serine-rich coiled-coil 1 -2.33693
CDK4 cyclin-dependent kinase 4 -2.31388
FPGS folylpolyglutamate synthase -2.31369
MRPS2 mitochondrial ribosomal protein S2 -2.30987
ZBBX zinc finger, B-box domain containing -2.25669
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.17917
CCDC81 coiled-coil domain containing 81 -2.14824
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -2.08771
TMEM230 transmembrane protein 230 -2.05368
CNPY3 canopy FGF signaling regulator 3 -2.02746
AGBL2 ATP/GTP binding protein-like 2 -2.01334
TKT transketolase -2.00624