| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (e)-3h-indol-3-ylidenemethanol 101.84 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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64 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 5.95238 |
| CCDC92 | coiled-coil domain containing 92 | 5.2518 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.89255 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.6535 |
| WASF3 | WAS protein family, member 3 | 3.577 |
| AGR2 | anterior gradient 2 | 3.55425 |
| NOTCH1 | notch 1 | 3.5319 |
| KIF5C | kinesin family member 5C | 3.35462 |
| HOXA10 | homeobox A10 | 3.15795 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.7627 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.7132 |
| RTN3 | reticulon 3 | 2.68265 |
| MMP1 | matrix metallopeptidase 1 | 2.4534 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.43628 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 2.31565 |
| PCNA | proliferating cell nuclear antigen | 2.2184 |
| NRBF2 | nuclear receptor binding factor 2 | 2.17575 |
| TBC1D12 | TBC1 domain family, member 12 | 2.15915 |
| WDR37 | WD repeat domain 37 | 2.13455 |
| MEX3C | mex-3 RNA binding family member C | 2.1001 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 2.09165 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.08775 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 2.0629 |
| NPY1R | neuropeptide Y receptor Y1 | 2.0335 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 2.026 |
| MELK | maternal embryonic leucine zipper kinase | 2.01245 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 2.0105 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 2.0001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PMM2 | phosphomannomutase 2 | -5.36475 |
| CAB39 | calcium binding protein 39 | -5.1727 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.6189 |
| CORO1A | coronin, actin binding protein, 1A | -3.6903 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.86273 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -2.7712 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.72502 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.70795 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -2.44955 |
| RIPPLY2-CYB5R4 | RIPPLY2-CYB5R4 readthrough | -2.4296 |
| DDX47 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | -2.4194 |
| SLC30A10 | solute carrier family 30, member 10 | -2.29625 |
| ZNF750 | zinc finger protein 750 | -2.28605 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | -2.2607 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -2.18335 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -2.16885 |
| SH2D4A | SH2 domain containing 4A | -2.1481 |
| ADRM1 | adhesion regulating molecule 1 | -2.14545 |
| CPNE2 | copine II | -2.11785 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | -2.11225 |
| ADIPOR1 | adiponectin receptor 1 | -2.11145 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -2.10855 |
| SV2A | synaptic vesicle glycoprotein 2A | -2.10815 |
| PRKG2 | protein kinase, cGMP-dependent, type II | -2.1026 |
| SLC17A1 | solute carrier family 17 (organic anion transporter), member 1 | -2.094 |
| ADAMTSL3 | ADAMTS-like 3 | -2.08435 |
| CA4 | carbonic anhydrase IV | -2.07967 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -2.06875 |
| ITGA10 | integrin, alpha 10 | -2.04705 |
| FOXF1 | forkhead box F1 | -2.04075 |
| NHEJ1 | nonhomologous end-joining factor 1 | -2.0184 |
| GPR19 | G protein-coupled receptor 19 | -2.0142 |
| PRR13 | proline rich 13 | -2.01155 |
| KATNIP | katanin interacting protein | -2.00805 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -2.00175 |
| ANKRD28 | ankyrin repeat domain 28 | -2.00125 |
