CRCGN015_MCF10A.TP53.M_24H:A11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 33.95 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADAM10 ADAM metallopeptidase domain 10 5.44375
GPER1 G protein-coupled estrogen receptor 1 5.14888
SPAG4 sperm associated antigen 4 5.04555
HBB hemoglobin, beta 3.4779
EPHB2 EPH receptor B2 3.45109
TBC1D31 TBC1 domain family, member 31 2.52705
SPIN2B spindlin family, member 2B 2.3748
SLC75A1 solute carrier family 75 member 1 2.2764
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 2.09875
ADRA2C adrenoceptor alpha 2C 2.0978
MELK maternal embryonic leucine zipper kinase 2.0553
SSBP3 single stranded DNA binding protein 3 2.0512
BAMBI BMP and activin membrane-bound inhibitor 2.04205
STRA6 stimulated by retinoic acid 6 2.02615
RAB3A RAB3A, member RAS oncogene family 2.01775
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.0137

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -5.5477
PMM2 phosphomannomutase 2 -5.0931
TEX10 testis expressed 10 -5.01695
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.44353
CAB39 calcium binding protein 39 -4.23085
JMJD6 jumonji domain containing 6 -4.16695
RFC2 replication factor C (activator 1) 2, 40kDa -3.26308
MXRA7 matrix-remodelling associated 7 -3.21865
FPGS folylpolyglutamate synthase -3.1335
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.78535
ILK integrin-linked kinase -2.70065
CBR1 carbonyl reductase 1 -2.51275
DSE dermatan sulfate epimerase -2.42425
MED27 mediator complex subunit 27 -2.31757
PSRC1 proline/serine-rich coiled-coil 1 -2.3023
SRSF2 serine/arginine-rich splicing factor 2 -2.19378
SEC13 SEC13 homolog (S. cerevisiae) -2.12
CD81 CD81 molecule -2.09075
PCCB propionyl CoA carboxylase, beta polypeptide -2.07795
FAIM Fas apoptotic inhibitory molecule -2.0644
NGRN neugrin, neurite outgrowth associated -2.0504
CSF2 colony stimulating factor 2 (granulocyte-macrophage) -2.0442