| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | shahrm perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.57905 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 6.2035 |
| UGDH | UDP-glucose 6-dehydrogenase | 5.24755 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 5.0 |
| COMP | cartilage oligomeric matrix protein | 5.0 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.78436 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.73772 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 4.6763 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.52785 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.376 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 4.01628 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.91957 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.4743 |
| MELK | maternal embryonic leucine zipper kinase | 2.9936 |
| PRRX2 | paired related homeobox 2 | 2.9755 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 2.782 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.72028 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 2.66865 |
| WRN | Werner syndrome, RecQ helicase-like | 2.6484 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 2.50215 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.37225 |
| RASA4B | RAS p21 protein activator 4B | 2.2709 |
| OLFML1 | olfactomedin-like 1 | 2.26875 |
| IL11RA | interleukin 11 receptor, alpha | 2.25285 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.25275 |
| MX1 | MX dynamin-like GTPase 1 | 2.232 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.16109 |
| ZFHX3 | zinc finger homeobox 3 | 2.15295 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.14768 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 2.14123 |
| RASIP1 | Ras interacting protein 1 | 2.12505 |
| MRPL37 | mitochondrial ribosomal protein L37 | 2.1105 |
| CHN1 | chimerin 1 | 2.09515 |
| FXYD6-FXYD2 | FXYD6-FXYD2 readthrough | 2.0715 |
| SH2D4A | SH2 domain containing 4A | 2.06095 |
| ZNF268 | zinc finger protein 268 | 2.0147 |
| SGMS1 | sphingomyelin synthase 1 | 2.00555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -5.9596 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.7408 |
| C1QBP | complement component 1, q subcomponent binding protein | -4.86877 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -3.1652 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -3.14332 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.8734 |
| S100A8 | S100 calcium binding protein A8 | -2.74585 |
| EMC6 | ER membrane protein complex subunit 6 | -2.7228 |
| MPV17 | MpV17 mitochondrial inner membrane protein | -2.6903 |
| NCBP3 | nuclear cap binding subunit 3 | -2.58185 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | -2.58162 |
| HSPA1A | heat shock 70kDa protein 1A | -2.4168 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -2.3654 |
| GABARAP | GABA(A) receptor-associated protein | -2.33565 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.3251 |
| DUSP14 | dual specificity phosphatase 14 | -2.2148 |
| CTPS1 | CTP synthase 1 | -2.20605 |
| MFSD1 | major facilitator superfamily domain containing 1 | -2.19595 |
| RPS5 | ribosomal protein S5 | -2.1885 |
| LBHD1 | LBH domain containing 1 | -2.1554 |
| PREB | prolactin regulatory element binding | -2.1041 |
| NGRN | neugrin, neurite outgrowth associated | -2.1016 |
| DERL2 | derlin 2 | -2.09955 |
| IER3 | immediate early response 3 | -2.0745 |
| NUP88 | nucleoporin 88kDa | -2.0637 |
| SYNGR2 | synaptogyrin 2 | -2.06295 |
| ELP5 | elongator acetyltransferase complex subunit 5 | -2.03665 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.035 |
| APH1B | APH1B gamma secretase subunit | -2.02365 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -2.00505 |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | -2.0035 |
