CRCGN015_MCF10A.TP53.M_24H:A23 Gene Set
Genes
52 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.9778
|
|
E2F2
|
E2F transcription factor 2
|
4.9156
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.67525
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
3.64245
|
|
AGR2
|
anterior gradient 2
|
2.91445
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.8486
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.82282
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
2.52665
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
2.4727
|
|
CTSZ
|
cathepsin Z
|
2.4074
|
|
RLIM
|
ring finger protein, LIM domain interacting
|
2.3733
|
|
RPRD2
|
regulation of nuclear pre-mRNA domain containing 2
|
2.25845
|
|
GAPDHS
|
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
|
2.24085
|
|
CCT3
|
chaperonin containing TCP1, subunit 3 (gamma)
|
2.23525
|
|
SMU1
|
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
|
2.2158
|
|
RDX
|
radixin
|
2.19242
|
|
PABPC3
|
poly(A) binding protein, cytoplasmic 3
|
2.15645
|
|
FOXO4
|
forkhead box O4
|
2.10005
|
|
HOXD11
|
homeobox D11
|
2.0792
|
|
FOXJ3
|
forkhead box J3
|
2.04453
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.0435
|
|
R3HDM2
|
R3H domain containing 2
|
2.03685
|
|
STAT4
|
signal transducer and activator of transcription 4
|
2.02135
|
|
AARSD1
|
alanyl-tRNA synthetase domain containing 1
|
2.01895
|
|
CCL13
|
chemokine (C-C motif) ligand 13
|
2.0151
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.4974
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-5.2978
|
|
TCTA
|
T-cell leukemia translocation altered
|
-4.5568
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.51455
|
|
HMG20B
|
high mobility group 20B
|
-4.28302
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-4.2427
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.2137
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-3.51988
|
|
HTRA1
|
HtrA serine peptidase 1
|
-3.3076
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-3.1745
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.08725
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.71758
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.46865
|
|
EIF2D
|
eukaryotic translation initiation factor 2D
|
-2.44875
|
|
FBXO21
|
F-box protein 21
|
-2.38123
|
|
DAAM2
|
dishevelled associated activator of morphogenesis 2
|
-2.33245
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.32825
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
-2.28005
|
|
LINC02762
|
long intergenic non-protein coding RNA 2762
|
-2.23598
|
|
MYLK
|
myosin light chain kinase
|
-2.2201
|
|
PIH1D1
|
PIH1 domain containing 1
|
-2.1838
|
|
PARP16
|
poly (ADP-ribose) polymerase family, member 16
|
-2.1824
|
|
PAM16
|
presequence translocase-associated motor 16 homolog (S. cerevisiae)
|
-2.17935
|
|
KIF16B
|
kinesin family member 16B
|
-2.14725
|
|
CA2
|
carbonic anhydrase II
|
-2.10335
|
|
IER2
|
immediate early response 2
|
-2.0328
|
|
TMEM50B
|
transmembrane protein 50B
|
-2.0173
|
