| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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46 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 3.52548 |
| ZNF589 | zinc finger protein 589 | 3.37804 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.36234 |
| CERK | ceramide kinase | 3.35236 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 3.22332 |
| AGR2 | anterior gradient 2 | 3.12948 |
| COMP | cartilage oligomeric matrix protein | 3.08976 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.90338 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.83706 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.78982 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 2.7666 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.74345 |
| ELAC2 | elaC ribonuclease Z 2 | 2.66743 |
| TBX2 | T-box 2 | 2.6073 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 2.54212 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.50054 |
| FZD10 | frizzled class receptor 10 | 2.29984 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.25721 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.2061 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.19745 |
| HSPA1B | heat shock 70kDa protein 1B | 2.06258 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.05345 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 2.02852 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 2.0285 |
| NOSIP | nitric oxide synthase interacting protein | 2.00758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COTL1 | coactosin-like F-actin binding protein 1 | -3.69666 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.60989 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.50108 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.20317 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -3.19064 |
| NISCH | nischarin | -3.0274 |
| FOSL1 | FOS-like antigen 1 | -2.94979 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -2.66821 |
| HMG20B | high mobility group 20B | -2.60015 |
| CDK6 | cyclin-dependent kinase 6 | -2.56135 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.46184 |
| S100A8 | S100 calcium binding protein A8 | -2.4154 |
| ACY1 | aminoacylase 1 | -2.36586 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.33154 |
| TWF2 | twinfilin actin binding protein 2 | -2.31498 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -2.28656 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.26793 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.26077 |
| MSMO1 | methylsterol monooxygenase 1 | -2.22801 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -2.03293 |
| OSMR | oncostatin M receptor | -2.03238 |
