CRCGN015_MCF10A.TP53.M_24H:B05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RAB21 RAB21, member RAS oncogene family 4.60298
EGF epidermal growth factor 3.40227
ADGRE5 adhesion G protein-coupled receptor E5 3.06268
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.62793
ACAA1 acetyl-CoA acyltransferase 1 2.49443
CARMIL1 capping protein regulator and myosin 1 linker 1 2.45545
MAMLD1 mastermind-like domain containing 1 2.42048
MELK maternal embryonic leucine zipper kinase 2.39956
STRN4 striatin, calmodulin binding protein 4 2.28651
ARID5B AT rich interactive domain 5B (MRF1-like) 2.24526
TBC1D15 TBC1 domain family, member 15 2.15307
COMP cartilage oligomeric matrix protein 2.11924
COPS7A COP9 signalosome subunit 7A 2.04854
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.0417
ACLY ATP citrate lyase 2.03067

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -4.07141
ANXA2 annexin A2 -3.70509
COG2 component of oligomeric golgi complex 2 -3.49933
SCYL3 SCY1-like 3 (S. cerevisiae) -3.17072
RPS5 ribosomal protein S5 -3.13385
CD81 CD81 molecule -2.02199