| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2s)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid 96.91 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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93 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCOLN1 | mucolipin 1 | 5.5879 |
| ABHD6 | abhydrolase domain containing 6 | 5.27227 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 4.90485 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 3.7789 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.6819 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.61045 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.34995 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | 3.06885 |
| GATA3 | GATA binding protein 3 | 3.02242 |
| PRR7 | proline rich 7 (synaptic) | 2.99845 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa | 2.8353 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 | 2.72085 |
| CBR4 | carbonyl reductase 4 | 2.59955 |
| KDSR | 3-ketodihydrosphingosine reductase | 2.53325 |
| TRIM37 | tripartite motif containing 37 | 2.5056 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.4754 |
| RBBP8 | retinoblastoma binding protein 8 | 2.46345 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | 2.4322 |
| CERS2 | ceramide synthase 2 | 2.4231 |
| TTC17 | tetratricopeptide repeat domain 17 | 2.4146 |
| ZNF451 | zinc finger protein 451 | 2.4008 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 2.3796 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | 2.371 |
| MAVS | mitochondrial antiviral signaling protein | 2.3132 |
| WASF3 | WAS protein family, member 3 | 2.30985 |
| H2AC19 | H2A clustered histone 19 | 2.29282 |
| CES1 | carboxylesterase 1 | 2.26915 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | 2.262 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 | 2.22405 |
| SECISBP2 | SECIS binding protein 2 | 2.21745 |
| NOP2 | NOP2 nucleolar protein | 2.19815 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 2.1725 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 2.1355 |
| LILRB5 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 | 2.1198 |
| NBPF3 | neuroblastoma breakpoint family, member 3 | 2.1016 |
| TRAPPC8 | trafficking protein particle complex 8 | 2.08685 |
| FUS | FUS RNA binding protein | 2.04725 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 2.0443 |
| DAPK3 | death-associated protein kinase 3 | 2.04345 |
| ACP5 | acid phosphatase 5, tartrate resistant | 2.034 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | 2.02095 |
| YJU2B | YJU2 splicing factor homolog B | 2.0177 |
| IL1B | interleukin 1, beta | 2.01732 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa | 2.008 |
| MARCHF2 | membrane associated ring-CH-type finger 2 | 2.0042 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 2.0022 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF14 | kinesin family member 14 | -5.15385 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.0 |
| SLC35F2 | solute carrier family 35, member F2 | -4.81165 |
| PGAM4 | phosphoglycerate mutase family member 4 | -4.69525 |
| CCNB1 | cyclin B1 | -4.6456 |
| VDAC1 | voltage-dependent anion channel 1 | -4.04922 |
| CLTB | clathrin, light chain B | -3.9565 |
| HEATR1 | HEAT repeat containing 1 | -3.48848 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.34205 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.16275 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -2.94115 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | -2.5921 |
| CDX1 | caudal type homeobox 1 | -2.5691 |
| GFUS | GDP-L-fucose synthase | -2.5093 |
| GSTT2B | glutathione S-transferase theta 2B (gene/pseudogene) | -2.49355 |
| NGRN | neugrin, neurite outgrowth associated | -2.39255 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.37875 |
| CDK1 | cyclin-dependent kinase 1 | -2.35822 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -2.32585 |
| CCNP | cyclin P | -2.31235 |
| DIABLO | diablo, IAP-binding mitochondrial protein | -2.31225 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | -2.31115 |
| NHP2 | NHP2 ribonucleoprotein | -2.308 |
| FGF9 | fibroblast growth factor 9 | -2.30425 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -2.2777 |
| RPL36AL | ribosomal protein L36a-like | -2.27105 |
| SFXN1 | sideroflexin 1 | -2.2351 |
| RTRAF | RNA transcription, translation and transport factor | -2.22915 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -2.22615 |
| IL21R | interleukin 21 receptor | -2.20557 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -2.19145 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -2.17457 |
| GPA33 | glycoprotein A33 (transmembrane) | -2.1402 |
| TENT5A | terminal nucleotidyltransferase 5A | -2.13885 |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | -2.13065 |
| DGKD | diacylglycerol kinase, delta 130kDa | -2.11395 |
| SPX | spexin hormone | -2.09845 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -2.08645 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma | -2.08463 |
| AEN | apoptosis enhancing nuclease | -2.079 |
| PGK1 | phosphoglycerate kinase 1 | -2.07158 |
| RWDD1 | RWD domain containing 1 | -2.0712 |
| WWC1 | WW and C2 domain containing 1 | -2.06837 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | -2.06345 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | -2.0593 |
| CANT1 | calcium activated nucleotidase 1 | -2.04947 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | -2.04485 |
