| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfuric acid compound with 2-methyl-1,4-benzenediamine (1:1) 33.45 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
114 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNRIP1 | cannabinoid receptor interacting protein 1 | 5.0 |
| SPAG4 | sperm associated antigen 4 | 4.9437 |
| TBX2 | T-box 2 | 4.51837 |
| TXNRD1 | thioredoxin reductase 1 | 4.1978 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.0325 |
| EPHB2 | EPH receptor B2 | 3.46609 |
| HMOX1 | heme oxygenase 1 | 3.26455 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.10145 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 3.06678 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 3.03165 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 3.01195 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.96675 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 2.8729 |
| CALCB | calcitonin-related polypeptide beta | 2.6894 |
| AUP1 | ancient ubiquitous protein 1 | 2.6125 |
| ZNF593 | zinc finger protein 593 | 2.6004 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 2.59405 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.5789 |
| TLCD3A | TLC domain containing 3A | 2.5297 |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 | 2.51682 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 2.499 |
| CCNA1 | cyclin A1 | 2.4988 |
| ACBD3 | acyl-CoA binding domain containing 3 | 2.47363 |
| TBPL1 | TBP-like 1 | 2.46885 |
| LAX1 | lymphocyte transmembrane adaptor 1 | 2.46535 |
| HKDC1 | hexokinase domain containing 1 | 2.46185 |
| TBXAS1 | thromboxane A synthase 1 (platelet) | 2.43285 |
| ZNF706 | zinc finger protein 706 | 2.3992 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.3992 |
| CTSL | cathepsin L | 2.3906 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.34775 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 2.3459 |
| TDO2 | tryptophan 2,3-dioxygenase | 2.3454 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 2.33455 |
| DNASE1L1 | deoxyribonuclease I-like 1 | 2.31335 |
| NRIP3 | nuclear receptor interacting protein 3 | 2.25985 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 2.2109 |
| CYB5R1 | cytochrome b5 reductase 1 | 2.20185 |
| OSBPL3 | oxysterol binding protein-like 3 | 2.1786 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 2.16505 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 | 2.164 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | 2.1355 |
| CALCA | calcitonin-related polypeptide alpha | 2.12189 |
| TEX10 | testis expressed 10 | 2.11765 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | 2.11645 |
| TENT5C | terminal nucleotidyltransferase 5C | 2.11325 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 2.1058 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 2.09685 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 2.09685 |
| GLRX | glutaredoxin (thioltransferase) | 2.0711 |
| SLC35B1 | solute carrier family 35, member B1 | 2.0698 |
| MERTK | MER proto-oncogene, tyrosine kinase | 2.04023 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.03315 |
| VILL | villin-like | 2.02605 |
| MVP | major vault protein | 2.02365 |
| APOL6 | apolipoprotein L, 6 | 2.0171 |
| ZBP1 | Z-DNA binding protein 1 | 2.01385 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.00217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF14 | kinesin family member 14 | -5.74105 |
| LDHD | lactate dehydrogenase D | -5.3681 |
| THAP11 | THAP domain containing 11 | -5.3279 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -4.80453 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.76405 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -4.60687 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.5247 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.34445 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.85255 |
| TNIP1 | TNFAIP3 interacting protein 1 | -3.83635 |
| ATF5 | activating transcription factor 5 | -3.5624 |
| NGRN | neugrin, neurite outgrowth associated | -3.3094 |
| KRT14 | keratin 14, type I | -3.2807 |
| RPS5 | ribosomal protein S5 | -3.2598 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -3.2432 |
| TRIB3 | tribbles pseudokinase 3 | -3.0217 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.7868 |
| KRT5 | keratin 5, type II | -2.7423 |
| CBX6 | chromobox homolog 6 | -2.72463 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -2.59315 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -2.56405 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.5514 |
| KIF20A | kinesin family member 20A | -2.5193 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | -2.5112 |
| MAGEF1 | melanoma antigen family F1 | -2.51085 |
| ATP11B | ATPase, class VI, type 11B | -2.45385 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -2.34765 |
| IGSF3 | immunoglobulin superfamily, member 3 | -2.3334 |
| TMEM168 | transmembrane protein 168 | -2.28615 |
| STMN1 | stathmin 1 | -2.27075 |
| RARS1 | arginyl-tRNA synthetase 1 | -2.2347 |
| CCNB2 | cyclin B2 | -2.22595 |
| REPIN1 | replication initiator 1 | -2.2221 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -2.2211 |
| HDAC3 | histone deacetylase 3 | -2.1863 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | -2.1841 |
| HOXC10 | homeobox C10 | -2.1835 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -2.18145 |
| RAD51AP1 | RAD51 associated protein 1 | -2.16145 |
| YEATS4 | YEATS domain containing 4 | -2.14945 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | -2.1335 |
| TMEM132A | transmembrane protein 132A | -2.12805 |
| PHB2 | prohibitin 2 | -2.11615 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -2.1153 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -2.1095 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.10205 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | -2.09315 |
| TTK | TTK protein kinase | -2.0766 |
| RBM15B | RNA binding motif protein 15B | -2.07445 |
| E2F8 | E2F transcription factor 8 | -2.06515 |
| DOCK4 | dedicator of cytokinesis 4 | -2.06295 |
| FAIM | Fas apoptotic inhibitory molecule | -2.0608 |
| ADISSP | adipose secreted signaling protein | -2.0552 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -2.0503 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -2.01735 |
| HOXC11 | homeobox C11 | -2.0121 |
