CRCGN015_MCF10A.TP53.M_24H:B13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hp163 perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

26 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GFOD1 glucose-fructose oxidoreductase domain containing 1 5.59435
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 4.91075
SNX11 sorting nexin 11 3.57275
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.14246
NOTCH1 notch 1 2.9822
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.93605
TXNRD1 thioredoxin reductase 1 2.8141
CCNF cyclin F 2.72733
CD40 CD40 molecule, TNF receptor superfamily member 5 2.72609
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.36805
GADD45A growth arrest and DNA-damage-inducible, alpha 2.35185
COMP cartilage oligomeric matrix protein 2.2862
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.21025
NCALD neurocalcin delta 2.1591
UBQLN2 ubiquilin 2 2.15485
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.128
BLMH bleomycin hydrolase 2.09685

decreased expression

Symbol Name Standardized Value
CHMP4B charged multivesicular body protein 4B -5.42718
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.6341
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.18065
ANXA2 annexin A2 -4.04565
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.65483
ATP11B ATPase, class VI, type 11B -2.3983
CD320 CD320 molecule -2.3613
MRM3 mitochondrial rRNA methyltransferase 3 -2.0086
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.004