CRCGN015_MCF10A.TP53.M_24H:B14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hp163 perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 6.59853
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.46422
MAP7 microtubule-associated protein 7 4.30307
DENND2D DENN/MADD domain containing 2D 3.86
LYN LYN proto-oncogene, Src family tyrosine kinase 2.56623
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.4383
MBNL1 muscleblind-like splicing regulator 1 2.31729
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.279
ACAA1 acetyl-CoA acyltransferase 1 2.12972
GSTZ1 glutathione S-transferase zeta 1 2.0651
H2AZ2 H2A.Z variant histone 2 2.04408
CNRIP1 cannabinoid receptor interacting protein 1 2.02045

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -5.04865
UBE3C ubiquitin protein ligase E3C -4.0153
PRCP prolylcarboxypeptidase (angiotensinase C) -3.54105
NGRN neugrin, neurite outgrowth associated -2.5591
PCCB propionyl CoA carboxylase, beta polypeptide -2.2538
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.1202
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -2.0404