CRCGN015_MCF10A.TP53.M_24H:B18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 5.0558
INTS3 integrator complex subunit 3 4.63245
ACAA1 acetyl-CoA acyltransferase 1 3.61085
FZD7 frizzled class receptor 7 3.32535
STK10 serine/threonine kinase 10 3.32352
CXCL3 chemokine (C-X-C motif) ligand 3 3.17585
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.60955
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.41695
DENND2D DENN/MADD domain containing 2D 2.1039

decreased expression

Symbol Name Standardized Value
CTNND1 catenin (cadherin-associated protein), delta 1 -5.18387
PTK2 protein tyrosine kinase 2 -3.91467
BASP1 brain abundant, membrane attached signal protein 1 -3.1838
RGS2 regulator of G-protein signaling 2 -2.94905
PSRC1 proline/serine-rich coiled-coil 1 -2.56595
PCCB propionyl CoA carboxylase, beta polypeptide -2.3017
RAD51C RAD51 paralog C -2.2041
CBR3 carbonyl reductase 3 -2.05985
TMX2 thioredoxin-related transmembrane protein 2 -2.03575
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.0107