| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tryptamine 33.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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139 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COMP | cartilage oligomeric matrix protein | 5.45367 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.62963 |
| ABHD6 | abhydrolase domain containing 6 | 4.25224 |
| METRN | meteorin, glial cell differentiation regulator | 3.84042 |
| TENT4A | terminal nucleotidyltransferase 4A | 3.68473 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.66037 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 3.65589 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.3075 |
| THAP7 | THAP domain containing 7 | 3.08936 |
| NOSIP | nitric oxide synthase interacting protein | 2.90237 |
| MED15 | mediator complex subunit 15 | 2.76496 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 2.70993 |
| EML3 | echinoderm microtubule associated protein like 3 | 2.65011 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.55583 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.55385 |
| TPD52L2 | tumor protein D52-like 2 | 2.53613 |
| SECTM1 | secreted and transmembrane 1 | 2.50506 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 2.48651 |
| EGF | epidermal growth factor | 2.46473 |
| COPS7A | COP9 signalosome subunit 7A | 2.45355 |
| ARHGAP9 | Rho GTPase activating protein 9 | 2.44635 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 2.43574 |
| TGFB3 | transforming growth factor, beta 3 | 2.41217 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 2.40491 |
| IER5 | immediate early response 5 | 2.39015 |
| IL4R | interleukin 4 receptor | 2.3539 |
| SCAMP5 | secretory carrier membrane protein 5 | 2.3297 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 2.32622 |
| NOTCH1 | notch 1 | 2.32304 |
| POLM | polymerase (DNA directed), mu | 2.32207 |
| TRIB1 | tribbles pseudokinase 1 | 2.30522 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 2.2937 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 | 2.24729 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 2.23392 |
| IFI35 | interferon-induced protein 35 | 2.23286 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | 2.23277 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.23105 |
| CHKB | choline kinase beta | 2.22427 |
| KRI1 | KRI1 homolog (S. cerevisiae) | 2.21252 |
| DGCR6L | DiGeorge syndrome critical region gene 6-like | 2.20227 |
| MCOLN1 | mucolipin 1 | 2.1951 |
| PRODH | proline dehydrogenase (oxidase) 1 | 2.18901 |
| CDK5 | cyclin-dependent kinase 5 | 2.17825 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 | 2.16561 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) | 2.1632 |
| SNAP29 | synaptosomal-associated protein, 29kDa | 2.16288 |
| ACP5 | acid phosphatase 5, tartrate resistant | 2.15631 |
| IRF7 | interferon regulatory factor 7 | 2.13269 |
| ASPN | asporin | 2.13004 |
| TMEM265 | transmembrane protein 265 | 2.11617 |
| BRD9 | bromodomain containing 9 | 2.10238 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.09273 |
| LAP3 | leucine aminopeptidase 3 | 2.09171 |
| KIAA1614 | KIAA1614 | 2.06261 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 2.0589 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 2.05662 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 | 2.045 |
| PDE9A | phosphodiesterase 9A | 2.04396 |
| GTPBP2 | GTP binding protein 2 | 2.03286 |
| MUC1 | mucin 1, cell surface associated | 2.03254 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.02457 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 | 2.0211 |
| SMIM40 | small integral membrane protein 40 | 2.01783 |
| PLXNB2 | plexin B2 | 2.01239 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.00188 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.42538 |
| THAP11 | THAP domain containing 11 | -5.36667 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -5.0596 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.54084 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -3.45117 |
| PLSCR3 | phospholipid scramblase 3 | -3.38151 |
| SPAG7 | sperm associated antigen 7 | -3.37932 |
| KRT14 | keratin 14, type I | -3.33521 |
| CRTAP | cartilage associated protein | -3.11126 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -3.1029 |
| LDHD | lactate dehydrogenase D | -3.05712 |
| ANXA2 | annexin A2 | -3.0554 |
| RPS5 | ribosomal protein S5 | -3.04021 |
| FER | fer (fps/fes related) tyrosine kinase | -2.86624 |
| TCERG1 | transcription elongation regulator 1 | -2.83119 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.74218 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.7347 |
| CDK6 | cyclin-dependent kinase 6 | -2.71498 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.65314 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.63843 |
| CCNG1 | cyclin G1 | -2.61968 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.58577 |
| PYGL | phosphorylase, glycogen, liver | -2.55036 |
| NUP88 | nucleoporin 88kDa | -2.54219 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -2.49951 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -2.44502 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.44275 |
| CCNA2 | cyclin A2 | -2.44147 |
| ELAVL1 | ELAV like RNA binding protein 1 | -2.43297 |
| NCK2 | NCK adaptor protein 2 | -2.3486 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | -2.34624 |
| EML4 | echinoderm microtubule associated protein like 4 | -2.33526 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -2.31562 |
| SLC25A46 | solute carrier family 25, member 46 | -2.30549 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | -2.29444 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -2.29383 |
| MELTF | melanotransferrin | -2.2719 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.2616 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -2.25124 |
| HDGFL3 | HDGF like 3 | -2.24432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -2.23961 |
| ECD | ecdysoneless homolog (Drosophila) | -2.23723 |
| CD320 | CD320 molecule | -2.23619 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -2.23531 |
| ZMYND11 | zinc finger, MYND-type containing 11 | -2.23483 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.2291 |
| CD81 | CD81 molecule | -2.22405 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -2.20942 |
| RANBP2 | RAN binding protein 2 | -2.18381 |
| LMAN1 | lectin, mannose-binding, 1 | -2.18253 |
| RSU1 | Ras suppressor protein 1 | -2.16164 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | -2.14703 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | -2.14534 |
| CBFB | core-binding factor, beta subunit | -2.12265 |
| CASC3 | cancer susceptibility candidate 3 | -2.11805 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.1095 |
| CHPT1 | choline phosphotransferase 1 | -2.10461 |
| GNAS | GNAS complex locus | -2.10275 |
| CUL4B | cullin 4B | -2.10186 |
| RPL3L | ribosomal protein L3-like | -2.09717 |
| MLEC | malectin | -2.09494 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | -2.07733 |
| SLC35F2 | solute carrier family 35, member F2 | -2.07346 |
| GDI2 | GDP dissociation inhibitor 2 | -2.0685 |
| HOXB9 | homeobox B9 | -2.05952 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.05778 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -2.05594 |
| CCKBR | cholecystokinin B receptor | -2.03834 |
| SYPL1 | synaptophysin-like 1 | -2.02893 |
| IFNA13 | interferon, alpha 13 | -2.01153 |
| CCDC85C | coiled-coil domain containing 85C | -2.0073 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -2.00387 |
| STMN1 | stathmin 1 | -2.00087 |
| NNT | nicotinamide nucleotide transhydrogenase | -2.00037 |
