CRCGN015_MCF10A.TP53.M_24H:C03 Gene Set
Genes
45 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.02733
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.81729
|
|
SESN1
|
sestrin 1
|
3.65698
|
|
TCTN1
|
tectonic family member 1
|
3.60697
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.46483
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.34689
|
|
CDCA4
|
cell division cycle associated 4
|
3.33168
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
3.28874
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.20248
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.88571
|
|
TBX2
|
T-box 2
|
2.85381
|
|
SPAG4
|
sperm associated antigen 4
|
2.80005
|
|
RNF167
|
ring finger protein 167
|
2.57921
|
|
COQ8A
|
coenzyme Q8A
|
2.41393
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.32338
|
|
KIF5C
|
kinesin family member 5C
|
2.29617
|
|
HOXA10
|
homeobox A10
|
2.24586
|
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1
|
2.24173
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.20173
|
|
HBB
|
hemoglobin, beta
|
2.1778
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
2.08724
|
|
CHMP1A
|
charged multivesicular body protein 1A
|
2.04019
|
|
LYRM1
|
LYR motif containing 1
|
2.02732
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.01677
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-4.07233
|
|
PMM2
|
phosphomannomutase 2
|
-3.97977
|
|
CD81
|
CD81 molecule
|
-3.43198
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-3.04636
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.60591
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.32721
|
|
CAB39
|
calcium binding protein 39
|
-2.24409
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.24196
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-2.19607
|
|
CDK2AP1
|
cyclin-dependent kinase 2 associated protein 1
|
-2.19303
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.17402
|
|
CRTAP
|
cartilage associated protein
|
-2.1389
|
|
SPRING1
|
SREBF pathway regulator in golgi 1
|
-2.11749
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
-2.08423
|
|
CWC25
|
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
|
-2.08018
|
|
AGO1
|
argonaute RISC catalytic component 1
|
-2.06109
|
|
CCDC68
|
coiled-coil domain containing 68
|
-2.04427
|
|
CYP26B1
|
cytochrome P450, family 26, subfamily B, polypeptide 1
|
-2.04297
|
|
LPGAT1
|
lysophosphatidylglycerol acyltransferase 1
|
-2.02684
|
|
DECR1
|
2,4-dienoyl CoA reductase 1, mitochondrial
|
-2.01998
|
|
TRMT11
|
tRNA methyltransferase 11 homolog (S. cerevisiae)
|
-2.01917
|
