CRCGN015_MCF10A.TP53.M_24H:C04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tranilast 100.0 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

537 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 9.53683
ALDOC aldolase C, fructose-bisphosphate 8.12795
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 7.1791
CAPN1 calpain 1, (mu/I) large subunit 5.46962
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.36086
TNIP1 TNFAIP3 interacting protein 1 5.18075
MUC1 mucin 1, cell surface associated 4.9681
RGS2 regulator of G-protein signaling 2 4.7933
TRAK2 trafficking protein, kinesin binding 2 4.74798
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.74772
KDM5A lysine (K)-specific demethylase 5A 4.50698
SCCPDH saccharopine dehydrogenase (putative) 4.29603
WIF1 WNT inhibitory factor 1 4.29505
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.26858
SPAG7 sperm associated antigen 7 4.24307
AGR2 anterior gradient 2 4.20614
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.14428
SQOR sulfide quinone oxidoreductase 4.07189
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.97292
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 3.90902
CEMIP2 cell migration inducing hyaluronidase 2 3.85217
GAA glucosidase, alpha; acid 3.80996
CCDC92 coiled-coil domain containing 92 3.76643
GLRX glutaredoxin (thioltransferase) 3.71825
IL4R interleukin 4 receptor 3.6806
IL1B interleukin 1, beta 3.66591
PPIC peptidylprolyl isomerase C (cyclophilin C) 3.64239
RAP1GAP RAP1 GTPase activating protein 3.60135
ECM1 extracellular matrix protein 1 3.53332
PLA2G15 phospholipase A2, group XV 3.52717
OXSR1 oxidative stress responsive 1 3.43637
STXBP1 syntaxin binding protein 1 3.39013
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.35783
HBB hemoglobin, beta 3.3472
PPARG peroxisome proliferator-activated receptor gamma 3.31667
STAMBP STAM binding protein 3.31566
PRAF2 PRA1 domain family, member 2 3.2654
SKIC2 SKI2 subunit of superkiller complex 3.25938
S100A4 S100 calcium binding protein A4 3.24909
CTSL cathepsin L 3.23065
E2F2 E2F transcription factor 2 3.20127
FDFT1 farnesyl-diphosphate farnesyltransferase 1 3.18645
WWC3 WWC family member 3 3.18493
CCL2 chemokine (C-C motif) ligand 2 3.17385
MVP major vault protein 3.16936
EPN2 epsin 2 3.1562
TICAM1 toll-like receptor adaptor molecule 1 3.14182
GPR137B G protein-coupled receptor 137B 3.09185
SYNE2 spectrin repeat containing, nuclear envelope 2 3.08341
NPC1 Niemann-Pick disease, type C1 3.07356
MINDY1 MINDY lysine 48 deubiquitinase 1 3.05527
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.04714
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.04439
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.04295
CDPF1 cysteine-rich, DPF motif domain containing 1 3.03452
VEGFC vascular endothelial growth factor C 2.981
EPHA2 EPH receptor A2 2.9783
DUSP4 dual specificity phosphatase 4 2.92853
FHL2 four and a half LIM domains 2 2.91781
COMP cartilage oligomeric matrix protein 2.90535
GALE UDP-galactose-4-epimerase 2.90236
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.89101
OMG oligodendrocyte myelin glycoprotein 2.88954
LRP10 low density lipoprotein receptor-related protein 10 2.88729
ALOX15B arachidonate 15-lipoxygenase, type B 2.88422
CNPY3 canopy FGF signaling regulator 3 2.84423
SLC44A1 solute carrier family 44 (choline transporter), member 1 2.82352
INPP1 inositol polyphosphate-1-phosphatase 2.82103
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.80191
EGR1 early growth response 1 2.78462
KRT24 keratin 24, type I 2.78141
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.77345
MORC4 MORC family CW-type zinc finger 4 2.76752
TMEM40 transmembrane protein 40 2.76701
G0S2 G0/G1 switch 2 2.7645
CXCR4 chemokine (C-X-C motif) receptor 4 2.76261
POMZP3 POM121 and ZP3 fusion 2.70483
NOTCH1 notch 1 2.68332
STX4 syntaxin 4 2.67198
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.6481
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.6285
ATG2A autophagy related 2A 2.61229
MAPK13 mitogen-activated protein kinase 13 2.61067
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.5808
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.56564
IRF7 interferon regulatory factor 7 2.54411
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.54154
MAP6D1 MAP6 domain containing 1 2.5272
GSTZ1 glutathione S-transferase zeta 1 2.52505
PLAU plasminogen activator, urokinase 2.50921
TP53BP2 tumor protein p53 binding protein 2 2.50532
GRAMD2B GRAM domain containing 2B 2.49872
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.49107
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.46937
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.46454
LAGE3 L antigen family, member 3 2.46138
PROCR protein C receptor, endothelial 2.4563
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.44443
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.44176
CUEDC1 CUE domain containing 1 2.43308
CLDN7 claudin 7 2.42323
NT5E 5'-nucleotidase, ecto (CD73) 2.41637
SLC22A17 solute carrier family 22, member 17 2.41543
ZCCHC24 zinc finger, CCHC domain containing 24 2.41042
MMP24OS MMP24 opposite strand 2.40831
ATOSB atos homolog B 2.40314
STAP2 signal transducing adaptor family member 2 2.4008
ACAA1 acetyl-CoA acyltransferase 1 2.39714
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.38883
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.38846
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.37175
NBEAL2 neurobeachin-like 2 2.37123
RRAS related RAS viral (r-ras) oncogene homolog 2.36632
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.35464
TEX2 testis expressed 2 2.35302
RNF122 ring finger protein 122 2.35057
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.34394
SIGLEC15 sialic acid binding Ig-like lectin 15 2.32765
RGS18 regulator of G-protein signaling 18 2.32616
TRIM22 tripartite motif containing 22 2.31808
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.30492
TP53I3 tumor protein p53 inducible protein 3 2.3043
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.30197
EFS embryonal Fyn-associated substrate 2.30094
CSRNP3 cysteine-serine-rich nuclear protein 3 2.29646
DUSP6 dual specificity phosphatase 6 2.28973
RAB5B RAB5B, member RAS oncogene family 2.28537
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.2785
TMEM184B transmembrane protein 184B 2.27809
CSNK1E casein kinase 1, epsilon 2.27411
GDI1 GDP dissociation inhibitor 1 2.26805
TSPAN15 tetraspanin 15 2.25994
IL33 interleukin 33 2.23801
TUBG2 tubulin, gamma 2 2.23759
SLC16A6 solute carrier family 16, member 6 2.23333
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.23291
PPME1 protein phosphatase methylesterase 1 2.22474
CTSB cathepsin B 2.22165
IRF9 interferon regulatory factor 9 2.21871
ACADVL acyl-CoA dehydrogenase, very long chain 2.21001
GATA2 GATA binding protein 2 2.20856
ZGPAT zinc finger, CCCH-type with G patch domain 2.20835
C2CD3 C2 calcium-dependent domain containing 3 2.20563
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 2.20318
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 2.20214
MITF microphthalmia-associated transcription factor 2.20148
FRMD4B FERM domain containing 4B 2.19978
PLAUR plasminogen activator, urokinase receptor 2.19614
MTMR11 myotubularin related protein 11 2.19542
ZDHHC3 zinc finger, DHHC-type containing 3 2.19373
SRPK3 SRSF protein kinase 3 2.18999
DNASE1L1 deoxyribonuclease I-like 1 2.1897
MICALL1 MICAL-like 1 2.188
MACROD1 MACRO domain containing 1 2.18229
RSF1 remodeling and spacing factor 1 2.18076
GPX2 glutathione peroxidase 2 2.17963
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.17448
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.17143
HMGXB4 HMG box domain containing 4 2.1706
ADRB2 adrenoceptor beta 2, surface 2.16678
TIAM1 T-cell lymphoma invasion and metastasis 1 2.16589
ZFYVE16 zinc finger, FYVE domain containing 16 2.16201
HSPB1 heat shock 27kDa protein 1 2.15986
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.15791
TMEM265 transmembrane protein 265 2.13678
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 2.13617
TM7SF2 transmembrane 7 superfamily member 2 2.13378
IER5 immediate early response 5 2.12926
TMEM212 transmembrane protein 212 2.12608
TRIM62 tripartite motif containing 62 2.12212
GGTLC1 gamma-glutamyltransferase light chain 1 2.11684
IFI6 interferon, alpha-inducible protein 6 2.11634
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.11202
IL1A interleukin 1, alpha 2.10707
TM7SF3 transmembrane 7 superfamily member 3 2.1051
ASL argininosuccinate lyase 2.1034
ORAI3 ORAI calcium release-activated calcium modulator 3 2.09836
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.0914
ELMO3 engulfment and cell motility 3 2.09084
ZC4H2 zinc finger, C4H2 domain containing 2.08372
TUBB6 tubulin, beta 6 class V 2.08276
TMEM53 transmembrane protein 53 2.08131
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.07799
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.07717
CHIC2 cysteine-rich hydrophobic domain 2 2.07699
SYNPO2 synaptopodin 2 2.07517
ARHGAP29 Rho GTPase activating protein 29 2.07335
WDTC1 WD and tetratricopeptide repeats 1 2.07322
PDZD2 PDZ domain containing 2 2.07307
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.07136
TERF2IP telomeric repeat binding factor 2, interacting protein 2.07092
MLPH melanophilin 2.07073
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.07005
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.06841
LAMA5 laminin, alpha 5 2.06766
HBEGF heparin-binding EGF-like growth factor 2.06718
PODNL1 podocan-like 1 2.06077
EHD1 EH-domain containing 1 2.05969
SAMD14 sterile alpha motif domain containing 14 2.05558
GBA1 glucosylceramidase beta 1 2.0539
TBC1D2 TBC1 domain family, member 2 2.0528
MICU1 mitochondrial calcium uptake 1 2.05259
PMP22 peripheral myelin protein 22 2.04992
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.04862
PLS1 plastin 1 2.04507
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.04004
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.03211
HYI hydroxypyruvate isomerase (putative) 2.02716
OSBPL2 oxysterol binding protein-like 2 2.02614
SCAND1 SCAN domain containing 1 2.025
HBA1 hemoglobin, alpha 1 2.02467
OASL 2'-5'-oligoadenylate synthetase-like 2.02186
LTB lymphotoxin beta (TNF superfamily, member 3) 2.01836
SYNGAP1 synaptic Ras GTPase activating protein 1 2.01791
KIF3A kinesin family member 3A 2.01676
NUCB2 nucleobindin 2 2.01595
ADAMTSL3 ADAMTS-like 3 2.01382
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.01173
GSPT2 G1 to S phase transition 2 2.01031
ADGRE5 adhesion G protein-coupled receptor E5 2.00941
DUSP5 dual specificity phosphatase 5 2.00875
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.00766

decreased expression

Symbol Name Standardized Value
ANKRD10 ankyrin repeat domain 10 -6.96471
HOXA5 homeobox A5 -5.8057
MCM3 minichromosome maintenance complex component 3 -5.79113
KIF20A kinesin family member 20A -5.5505
CCNB2 cyclin B2 -5.1605
PSRC1 proline/serine-rich coiled-coil 1 -5.0951
NT5DC2 5'-nucleotidase domain containing 2 -4.98841
CIRBP cold inducible RNA binding protein -4.94209
CDC25B cell division cycle 25B -4.92941
STMN1 stathmin 1 -4.78836
TOR1A torsin family 1, member A (torsin A) -4.7368
CDK4 cyclin-dependent kinase 4 -4.682
CD58 CD58 molecule -4.57802
EIF5 eukaryotic translation initiation factor 5 -4.5721
OXA1L oxidase (cytochrome c) assembly 1-like -4.4954
RPA3 replication protein A3, 14kDa -4.4641
ATF5 activating transcription factor 5 -4.45171
HSPA8 heat shock 70kDa protein 8 -4.4236
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.15809
HSPA1A heat shock 70kDa protein 1A -4.1509
GOLT1B golgi transport 1B -4.04822
HADH hydroxyacyl-CoA dehydrogenase -3.9358
UBE3C ubiquitin protein ligase E3C -3.93128
LBR lamin B receptor -3.89654
BIRC5 baculoviral IAP repeat containing 5 -3.62327
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -3.61608
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.5994
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -3.57252
TOP2A topoisomerase (DNA) II alpha 170kDa -3.49283
PCNA proliferating cell nuclear antigen -3.47881
SCARB1 scavenger receptor class B, member 1 -3.4587
TSC22D3 TSC22 domain family, member 3 -3.45105
ZNF274 zinc finger protein 274 -3.42572
KIF14 kinesin family member 14 -3.42241
CCNA2 cyclin A2 -3.42205
MRPL3 mitochondrial ribosomal protein L3 -3.39568
RPS5 ribosomal protein S5 -3.30436
CHEK1 checkpoint kinase 1 -3.28233
CENPA centromere protein A -3.26793
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -3.21624
TRAPPC3 trafficking protein particle complex 3 -3.19235
EML4 echinoderm microtubule associated protein like 4 -3.16248
EBNA1BP2 EBNA1 binding protein 2 -3.15962
UNC119B unc-119 homolog B (C. elegans) -3.14718
CANX calnexin -3.14201
NDC1 NDC1 transmembrane nucleoporin -3.13242
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.12103
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.10612
LYPLA1 lysophospholipase I -3.08288
NCAPD2 non-SMC condensin I complex, subunit D2 -3.07861
ZNF134 zinc finger protein 134 -3.05669
NOP16 NOP16 nucleolar protein -3.02225
TES testin LIM domain protein -3.00626
MCM10 minichromosome maintenance complex component 10 -3.00408
CAPRIN1 cell cycle associated protein 1 -2.99611
PLK1 polo-like kinase 1 -2.99568
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.96663
CDCA8 cell division cycle associated 8 -2.95949
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.92942
GRWD1 glutamate-rich WD repeat containing 1 -2.91986
AGPS alkylglycerone phosphate synthase -2.901
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.88847
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.88782
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -2.84584
TTC27 tetratricopeptide repeat domain 27 -2.84031
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.83515
HDAC2 histone deacetylase 2 -2.81099
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.81011
TMX1 thioredoxin-related transmembrane protein 1 -2.80228
SMNDC1 survival motor neuron domain containing 1 -2.7574
MBNL1 muscleblind-like splicing regulator 1 -2.75267
MAPKAP1 mitogen-activated protein kinase associated protein 1 -2.75248
PGRMC1 progesterone receptor membrane component 1 -2.74845
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.7442
INTS3 integrator complex subunit 3 -2.74047
PRUNE1 prune exopolyphosphatase 1 -2.73494
GABPA GA binding protein transcription factor, alpha subunit 60kDa -2.73245
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.72705
ILF2 interleukin enhancer binding factor 2 -2.72571
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.72269
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.72266
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.71828
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.69247
ATAD2 ATPase family, AAA domain containing 2 -2.68393
PIMREG PICALM interacting mitotic regulator -2.68048
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -2.67851
KIF18A kinesin family member 18A -2.67719
TTC1 tetratricopeptide repeat domain 1 -2.67148
SPDL1 spindle apparatus coiled-coil protein 1 -2.67035
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.66935
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.65861
RLIM ring finger protein, LIM domain interacting -2.64552
MKKS McKusick-Kaufman syndrome -2.63754
CD320 CD320 molecule -2.63499
CDCA4 cell division cycle associated 4 -2.63289
LIAS lipoic acid synthetase -2.63227
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.615
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.60865
FKBP5 FK506 binding protein 5 -2.60735
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.60568
SELENOF selenoprotein F -2.60394
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.5779
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.57088
PARP1 poly (ADP-ribose) polymerase 1 -2.56634
PRMT5 protein arginine methyltransferase 5 -2.56352
TMEM267 transmembrane protein 267 -2.55706
NXT2 nuclear transport factor 2-like export factor 2 -2.54624
SRPRB signal recognition particle receptor, B subunit -2.53504
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.52454
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.51592
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.51478
OIP5 Opa interacting protein 5 -2.51202
ZNF227 zinc finger protein 227 -2.5082
NPR2 natriuretic peptide receptor 2 -2.50132
VPS26C VPS26 endosomal protein sorting factor C -2.49956
RBMX RNA binding motif protein, X-linked -2.49155
CDC20 cell division cycle 20 -2.48762
PHB2 prohibitin 2 -2.48756
CBX3 chromobox homolog 3 -2.48186
ANXA2 annexin A2 -2.48016
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.47899
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.45942
SLC25A40 solute carrier family 25, member 40 -2.45851
BORA bora, aurora kinase A activator -2.45795
EIF3E eukaryotic translation initiation factor 3, subunit E -2.45343
NFIL3 nuclear factor, interleukin 3 regulated -2.45129
SRSF2 serine/arginine-rich splicing factor 2 -2.45113
DRC9 dynein regulatory complex subunit 9 -2.44981
PPID peptidylprolyl isomerase D -2.44718
CASC3 cancer susceptibility candidate 3 -2.44644
ATF4 activating transcription factor 4 -2.44058
RBM14-RBM4 RBM14-RBM4 readthrough -2.43954
CEP63 centrosomal protein 63kDa -2.4365
STOML2 stomatin (EPB72)-like 2 -2.43277
HOXA4 homeobox A4 -2.43062
RPL8 ribosomal protein L8 -2.42987
DEK DEK proto-oncogene -2.42963
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.4292
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -2.42093
TACC3 transforming, acidic coiled-coil containing protein 3 -2.41766
ZDHHC6 zinc finger, DHHC-type containing 6 -2.41624
MEMO1 mediator of cell motility 1 -2.41604
PPP6C protein phosphatase 6, catalytic subunit -2.41299
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.41
ANAPC1 anaphase promoting complex subunit 1 -2.40906
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.40072
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -2.39966
MFN1 mitofusin 1 -2.39907
TRIM28 tripartite motif containing 28 -2.39782
POLR1F RNA polymerase I subunit F -2.39585
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.39058
MSH2 mutS homolog 2 -2.38918
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.38902
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.38798
CENPN centromere protein N -2.3866
UBE2K ubiquitin-conjugating enzyme E2K -2.38559
PRC1 protein regulator of cytokinesis 1 -2.38534
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.38431
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.38421
SYBU syntabulin (syntaxin-interacting) -2.37281
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -2.36619
MCM9 minichromosome maintenance complex component 9 -2.36601
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.36596
PBK PDZ binding kinase -2.36151
MRPL15 mitochondrial ribosomal protein L15 -2.35888
DPH2 DPH2 homolog (S. cerevisiae) -2.35476
HMGB2 high mobility group box 2 -2.35438
PROSER1 proline and serine rich 1 -2.34929
ABHD17B abhydrolase domain containing 17B -2.34876
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.34703
CDC45 cell division cycle 45 -2.34408
RNASE7 ribonuclease, RNase A family, 7 -2.32738
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.32615
PARPBP PARP1 binding protein -2.32246
RARS1 arginyl-tRNA synthetase 1 -2.3221
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.31861
METTL4 methyltransferase like 4 -2.31518
CDC23 cell division cycle 23 -2.31401
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.31328
ANKRD49 ankyrin repeat domain 49 -2.31048
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.30958
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.30793
IPO5 importin 5 -2.30668
UTP11 UTP11 small subunit processome component -2.30328
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.30287
HMGB1 high mobility group box 1 -2.30089
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.29639
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -2.2944
SURF2 surfeit 2 -2.29251
SKA1 spindle and kinetochore associated complex subunit 1 -2.29206
CDC25C cell division cycle 25C -2.28996
TIPIN TIMELESS interacting protein -2.28587
ODAM odontogenic, ameloblast asssociated -2.28265
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.28086
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.27962
MED27 mediator complex subunit 27 -2.26824
SORBS3 sorbin and SH3 domain containing 3 -2.26652
SPAST spastin -2.26439
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -2.26415
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -2.26239
DCLRE1A DNA cross-link repair 1A -2.26218
CUL1 cullin 1 -2.25884
ATP5F1A ATP synthase F1 subunit alpha -2.25757
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.25342
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -2.25259
RNF130 ring finger protein 130 -2.25183
PGAM4 phosphoglycerate mutase family member 4 -2.2491
PRMT1 protein arginine methyltransferase 1 -2.24889
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.24569
RMDN1 regulator of microtubule dynamics 1 -2.24309
CYCS cytochrome c, somatic -2.24229
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.23807
ANKRD17 ankyrin repeat domain 17 -2.23588
ERI3 ERI1 exoribonuclease family member 3 -2.22644
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 -2.22529
EAPP E2F-associated phosphoprotein -2.21358
PCSK1 proprotein convertase subtilisin/kexin type 1 -2.2127
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.21027
ZMYM1 zinc finger, MYM-type 1 -2.20076
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -2.20013
DCK deoxycytidine kinase -2.1992
RIC8B RIC8 guanine nucleotide exchange factor B -2.19802
OXCT1 3-oxoacid CoA transferase 1 -2.19516
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.19418
HSPA14 heat shock 70kDa protein 14 -2.19357
SAP30L SAP30-like -2.19189
PTBP1 polypyrimidine tract binding protein 1 -2.18859
SNX7 sorting nexin 7 -2.18732
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.18061
CDK6 cyclin-dependent kinase 6 -2.18059
YME1L1 YME1-like 1 ATPase -2.17824
TRA2B transformer 2 beta homolog (Drosophila) -2.17471
NUP133 nucleoporin 133kDa -2.17436
PYCR1 pyrroline-5-carboxylate reductase 1 -2.17388
GDI2 GDP dissociation inhibitor 2 -2.17225
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.16905
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.16784
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.16049
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.15227
EXOC5 exocyst complex component 5 -2.15109
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.14839
MAEA macrophage erythroblast attacher -2.14504
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.14124
NUP205 nucleoporin 205kDa -2.14095
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.13718
ZNF207 zinc finger protein 207 -2.13679
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.13538
ZFAND1 zinc finger, AN1-type domain 1 -2.13353
ETF1 eukaryotic translation termination factor 1 -2.12581
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.12476
MRPL42 mitochondrial ribosomal protein L42 -2.12215
RAN RAN, member RAS oncogene family -2.11968
KIF15 kinesin family member 15 -2.11933
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.11758
TXNDC9 thioredoxin domain containing 9 -2.11725
YARS1 tyrosyl-tRNA synthetase 1 -2.1147
INTS14 integrator complex subunit 14 -2.11459
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.11417
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.10653
ENTR1 endosome associated trafficking regulator 1 -2.1045
UIMC1 ubiquitin interaction motif containing 1 -2.09875
SNX10 sorting nexin 10 -2.09851
CD164 CD164 molecule, sialomucin -2.09828
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.09705
CCNB1 cyclin B1 -2.09548
NKAPD1 NKAP domain containing 1 -2.09272
FBL fibrillarin -2.09243
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.0895
SNX17 sorting nexin 17 -2.08882
DCAF17 DDB1 and CUL4 associated factor 17 -2.08697
NHP2 NHP2 ribonucleoprotein -2.08568
TXLNG taxilin gamma -2.08514
DDIT4 DNA-damage-inducible transcript 4 -2.08505
SRSF1 serine/arginine-rich splicing factor 1 -2.08475
PABPC3 poly(A) binding protein, cytoplasmic 3 -2.08109
ASF1A anti-silencing function 1A histone chaperone -2.07915
TM9SF2 transmembrane 9 superfamily member 2 -2.07569
H2AZ1 H2A.Z variant histone 1 -2.07226
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.06969
ING1 inhibitor of growth family, member 1 -2.06914
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.06885
KIF4A kinesin family member 4A -2.06879
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.06698
MEAF6 MYST/Esa1-associated factor 6 -2.06565
TMCO1 transmembrane and coiled-coil domains 1 -2.06292
SNX4 sorting nexin 4 -2.05696
TMSB10 thymosin beta 10 -2.05599
NCKAP1 NCK-associated protein 1 -2.05178
ABHD10 abhydrolase domain containing 10 -2.05096
RESF1 retroelement silencing factor 1 -2.04968
NAXD NAD(P)HX dehydratase -2.04522
DNAAF2 dynein, axonemal, assembly factor 2 -2.04242
URM1 ubiquitin related modifier 1 -2.04029
POT1 protection of telomeres 1 -2.04009
MED17 mediator complex subunit 17 -2.03833
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.0321
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.02779
ATP5F1C ATP synthase F1 subunit gamma -2.02598
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.02287
NUSAP1 nucleolar and spindle associated protein 1 -2.02225
TXNL1 thioredoxin-like 1 -2.02222
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.02125
AK8 adenylate kinase 8 -2.01918
ZNF551 zinc finger protein 551 -2.01872
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.0163
RAD50 RAD50 homolog (S. cerevisiae) -2.01134
BEX3 brain expressed X-linked 3 -2.01109
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.00743
GFUS GDP-L-fucose synthase -2.00729
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.00698
SEC11A SEC11 homolog A (S. cerevisiae) -2.00606
UNC50 unc-50 homolog (C. elegans) -2.00592
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.00294
SERBP1 SERPINE1 mRNA binding protein 1 -2.00205
LRPPRC leucine-rich pentatricopeptide repeat containing -2.00037