| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tranilast 33.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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91 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.78924 |
| MPC2 | mitochondrial pyruvate carrier 2 | 4.11703 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 3.87344 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.47018 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.40859 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.35334 |
| CAPN1 | calpain 1, (mu/I) large subunit | 3.32415 |
| KLHL21 | kelch-like family member 21 | 2.91242 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.90688 |
| SQOR | sulfide quinone oxidoreductase | 2.88392 |
| ABHD6 | abhydrolase domain containing 6 | 2.86949 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.85692 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 2.75511 |
| MUC1 | mucin 1, cell surface associated | 2.72938 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.66402 |
| MOK | MOK protein kinase | 2.61977 |
| SPAG7 | sperm associated antigen 7 | 2.5137 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 2.45617 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.42756 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.40927 |
| S100A4 | S100 calcium binding protein A4 | 2.39495 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.31275 |
| STAMBP | STAM binding protein | 2.30725 |
| RGS2 | regulator of G-protein signaling 2 | 2.28263 |
| CTSL | cathepsin L | 2.27106 |
| CLDN7 | claudin 7 | 2.20998 |
| TLCD3A | TLC domain containing 3A | 2.17728 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.17565 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 2.14799 |
| EMILIN1 | elastin microfibril interfacer 1 | 2.14371 |
| FST | follistatin | 2.10756 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.09971 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.08987 |
| GALE | UDP-galactose-4-epimerase | 2.08619 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 | 2.0819 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.06637 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.0651 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 2.04854 |
| CDCA4 | cell division cycle associated 4 | 2.0446 |
| EGR1 | early growth response 1 | 2.04402 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 2.03689 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | 2.00101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ANKRD10 | ankyrin repeat domain 10 | -6.82475 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.80421 |
| YME1L1 | YME1-like 1 ATPase | -4.46965 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.20848 |
| VAT1 | vesicle amine transport 1 | -3.672 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.61685 |
| PCNA | proliferating cell nuclear antigen | -3.54156 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.52065 |
| ADI1 | acireductone dioxygenase 1 | -3.39811 |
| DSG2 | desmoglein 2 | -3.37733 |
| DCK | deoxycytidine kinase | -3.25693 |
| ACOT9 | acyl-CoA thioesterase 9 | -3.21038 |
| CDK4 | cyclin-dependent kinase 4 | -3.15769 |
| STMN1 | stathmin 1 | -3.0473 |
| GOLT1B | golgi transport 1B | -3.02947 |
| CIRBP | cold inducible RNA binding protein | -2.84892 |
| TXNDC9 | thioredoxin domain containing 9 | -2.84647 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -2.76708 |
| THAP11 | THAP domain containing 11 | -2.70908 |
| ATF5 | activating transcription factor 5 | -2.57159 |
| ZMYND11 | zinc finger, MYND-type containing 11 | -2.51508 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.51047 |
| OXCT1 | 3-oxoacid CoA transferase 1 | -2.47065 |
| ATP5F1C | ATP synthase F1 subunit gamma | -2.41847 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.38655 |
| HSPA14 | heat shock 70kDa protein 14 | -2.37011 |
| PRPF18 | pre-mRNA processing factor 18 | -2.36119 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.36057 |
| RGPD2 | RANBP2-like and GRIP domain containing 2 | -2.32992 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -2.31271 |
| CDK6 | cyclin-dependent kinase 6 | -2.29441 |
| FZD6 | frizzled class receptor 6 | -2.28666 |
| LYPLA1 | lysophospholipase I | -2.27585 |
| COMMD3 | COMM domain containing 3 | -2.27269 |
| MCM10 | minichromosome maintenance complex component 10 | -2.2295 |
| RPS5 | ribosomal protein S5 | -2.17226 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.16007 |
| ANXA2 | annexin A2 | -2.14135 |
| MCM3 | minichromosome maintenance complex component 3 | -2.12744 |
| GDI2 | GDP dissociation inhibitor 2 | -2.12283 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.08763 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -2.06972 |
| CD81 | CD81 molecule | -2.06575 |
| WAC | WW domain containing adaptor with coiled-coil | -2.05564 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -2.05409 |
| DNM1L | dynamin 1-like | -2.05082 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -2.02666 |
| VDAC1 | voltage-dependent anion channel 1 | -2.00815 |
| RAB32 | RAB32, member RAS oncogene family | -2.00251 |
