| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 15-delta-prostaglandin-j2 0.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPAG4 | sperm associated antigen 4 | 5.4404 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.25093 |
| TRIM13 | tripartite motif containing 13 | 5.227 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.72188 |
| TXNRD1 | thioredoxin reductase 1 | 3.93185 |
| HMOX1 | heme oxygenase 1 | 3.3613 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.31495 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.7855 |
| FAM50B | family with sequence similarity 50, member B | 2.57525 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.45845 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 2.3341 |
| IQCB1 | IQ motif containing B1 | 2.29535 |
| IL17B | interleukin 17B | 2.25785 |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 | 2.24277 |
| RINT1 | RAD50 interactor 1 | 2.2344 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 2.22905 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.18685 |
| SQSTM1 | sequestosome 1 | 2.17945 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 2.17585 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | 2.169 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.15715 |
| HGD | homogentisate 1,2-dioxygenase | 2.15162 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 2.1341 |
| FCHO1 | FCH domain only 1 | 2.1039 |
| LOC122526780 | uncharacterized LOC122526780 | 2.1017 |
| CTSL | cathepsin L | 2.09005 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 2.0866 |
| BIRC3 | baculoviral IAP repeat containing 3 | 2.05805 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase | 2.0139 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 2.01323 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.0055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBE3C | ubiquitin protein ligase E3C | -5.28095 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.2181 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.0 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -4.18848 |
| PFN1 | profilin 1 | -3.72815 |
| GNAS | GNAS complex locus | -3.67976 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.55245 |
| C1QBP | complement component 1, q subcomponent binding protein | -3.54252 |
| ANKRD10 | ankyrin repeat domain 10 | -3.47985 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -3.4103 |
| FUZ | fuzzy planar cell polarity protein | -3.1021 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -2.7929 |
| RPN2 | ribophorin II | -2.79188 |
| MXRA5 | matrix-remodelling associated 5 | -2.63295 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.607 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.5967 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | -2.5713 |
| NCBP3 | nuclear cap binding subunit 3 | -2.4598 |
| TTBK2 | tau tubulin kinase 2 | -2.4193 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -2.3954 |
| FOXM1 | forkhead box M1 | -2.27265 |
| WDR26 | WD repeat domain 26 | -2.2462 |
| ZNF281 | zinc finger protein 281 | -2.23545 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -2.18985 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -2.16685 |
| EMC6 | ER membrane protein complex subunit 6 | -2.1658 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -2.1634 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | -2.1492 |
| CCDC88C | coiled-coil domain containing 88C | -2.1478 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -2.1444 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.13075 |
| NPTX1 | neuronal pentraxin I | -2.0993 |
| LAG3 | lymphocyte-activation gene 3 | -2.0724 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -2.0577 |
| CES2 | carboxylesterase 2 | -2.01547 |
