CRCGN015_MCF10A.TP53.M_24H:C14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxyquinoline 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 4.81815
TBX2 T-box 2 4.23973
ACAA1 acetyl-CoA acyltransferase 1 3.35955
PRKX protein kinase, X-linked 2.43802
STAMBP STAM binding protein 2.31745
TLCD3A TLC domain containing 3A 2.1552
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.1271
CCDC85B coiled-coil domain containing 85B 2.07875
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.046

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -4.506
KRT14 keratin 14, type I -3.3377
KDM3A lysine (K)-specific demethylase 3A -3.0264
RALGDS ral guanine nucleotide dissociation stimulator -2.94198
NGRN neugrin, neurite outgrowth associated -2.7309
HEATR1 HEAT repeat containing 1 -2.61075
FPGS folylpolyglutamate synthase -2.56335
PIH1D1 PIH1 domain containing 1 -2.48455
HSPA1A heat shock 70kDa protein 1A -2.45195
ANKRD10 ankyrin repeat domain 10 -2.3035
BASP1 brain abundant, membrane attached signal protein 1 -2.22945
ZNRF4 zinc and ring finger 4 -2.02195