| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-nitronaphthalene 100.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 5.0744 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 4.6888 |
| LGMN | legumain | 3.7963 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 3.6953 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 3.0206 |
| ZNF451 | zinc finger protein 451 | 2.99735 |
| STAP2 | signal transducing adaptor family member 2 | 2.72945 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.69602 |
| ATP9A | ATPase, class II, type 9A | 2.6041 |
| PODXL2 | podocalyxin-like 2 | 2.59 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.55345 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 2.50911 |
| MICALL1 | MICAL-like 1 | 2.44517 |
| GTPBP8 | GTP-binding protein 8 (putative) | 2.4152 |
| METRN | meteorin, glial cell differentiation regulator | 2.2487 |
| MRGBP | MRG/MORF4L binding protein | 2.24445 |
| SLC9B2 | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 | 2.23785 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.2052 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.16045 |
| DENND2D | DENN/MADD domain containing 2D | 2.14655 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 2.1256 |
| TJP3 | tight junction protein 3 | 2.10352 |
| TRPS1 | trichorhinophalangeal syndrome I | 2.0998 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | 2.0736 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | 2.01775 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.00195 |
| MAT2B | methionine adenosyltransferase II, beta | 2.0014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -5.36895 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -5.20125 |
| GRN | granulin | -5.14693 |
| PUF60 | poly-U binding splicing factor 60KDa | -5.0 |
| MSMO1 | methylsterol monooxygenase 1 | -5.0 |
| TCTA | T-cell leukemia translocation altered | -4.98335 |
| RPS5 | ribosomal protein S5 | -4.1651 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -4.0737 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -3.66985 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -3.33456 |
| ANKRD10 | ankyrin repeat domain 10 | -3.32165 |
| ATP11B | ATPase, class VI, type 11B | -3.22665 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.19027 |
| SCRIB | scribbled planar cell polarity protein | -3.04595 |
| CANT1 | calcium activated nucleotidase 1 | -2.90445 |
| REXO2 | RNA exonuclease 2 | -2.88527 |
| GFUS | GDP-L-fucose synthase | -2.72825 |
| REEP5 | receptor accessory protein 5 | -2.48505 |
| NGRN | neugrin, neurite outgrowth associated | -2.34075 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -2.30268 |
| KRT6A | keratin 6A, type II | -2.24457 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.243 |
| EMC7 | ER membrane protein complex subunit 7 | -2.23465 |
| GPR183 | G protein-coupled receptor 183 | -2.23035 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -2.22473 |
| ERP29 | endoplasmic reticulum protein 29 | -2.2247 |
| KRT5 | keratin 5, type II | -2.22075 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -2.21918 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.1439 |
| ATP10D | ATPase, class V, type 10D | -2.10565 |
| EIF1B | eukaryotic translation initiation factor 1B | -2.0962 |
| DBF4 | DBF4 zinc finger | -2.045 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | -2.0369 |
| RPL27A | ribosomal protein L27a | -2.0364 |
| LGALS7B | lectin, galactoside-binding, soluble, 7B | -2.00895 |
| TMEM222 | transmembrane protein 222 | -2.00615 |
| PDCD6IP | programmed cell death 6 interacting protein | -2.00465 |
