| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-nitronaphthalene 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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95 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 5.2357 |
| SSBP2 | single-stranded DNA binding protein 2 | 5.0647 |
| ABHD4 | abhydrolase domain containing 4 | 4.5981 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 4.46247 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 4.1188 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.82205 |
| PFKL | phosphofructokinase, liver | 3.77997 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3.1651 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.12425 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 2.8135 |
| PTH1R | parathyroid hormone 1 receptor | 2.6616 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 | 2.66145 |
| FAM110B | family with sequence similarity 110, member B | 2.63485 |
| ADGRB1 | adhesion G protein-coupled receptor B1 | 2.6191 |
| DPT | dermatopontin | 2.59892 |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 | 2.51895 |
| POU3F2 | POU class 3 homeobox 2 | 2.5178 |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 | 2.5108 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | 2.4828 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 2.4408 |
| DUX4 | double homeobox 4 | 2.4094 |
| LOXL1 | lysyl oxidase-like 1 | 2.4051 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 2.37225 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 2.31588 |
| LOC102723996 | ICOS ligand | 2.28611 |
| ZNF385D | zinc finger protein 385D | 2.2765 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | 2.23612 |
| SH3GL1 | SH3-domain GRB2-like 1 | 2.23545 |
| AKTIP | AKT interacting protein | 2.2332 |
| SKI | SKI proto-oncogene | 2.2307 |
| IL17RB | interleukin 17 receptor B | 2.21355 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 2.2099 |
| XPA | xeroderma pigmentosum, complementation group A | 2.1761 |
| PITPNB | phosphatidylinositol transfer protein, beta | 2.1593 |
| PCNT | pericentrin | 2.1277 |
| PAX6 | paired box 6 | 2.1224 |
| PALM | paralemmin | 2.11385 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F | 2.1091 |
| NGRN | neugrin, neurite outgrowth associated | 2.1025 |
| SNTA1 | syntrophin, alpha 1 | 2.09375 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.09215 |
| DDTL | D-dopachrome tautomerase-like | 2.0788 |
| LMBR1 | limb development membrane protein 1 | 2.03547 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 2.0228 |
| EFNA3 | ephrin-A3 | 2.01625 |
| ZFHX4 | zinc finger homeobox 4 | 2.0126 |
| NCK1 | NCK adaptor protein 1 | 2.00965 |
| ZNF14 | zinc finger protein 14 | 2.0046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.053 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -4.9424 |
| RPA3 | replication protein A3, 14kDa | -4.86395 |
| PCNA | proliferating cell nuclear antigen | -4.66275 |
| YME1L1 | YME1-like 1 ATPase | -4.34697 |
| THAP11 | THAP domain containing 11 | -4.03665 |
| ANKRD10 | ankyrin repeat domain 10 | -3.5365 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.30447 |
| HSPA1A | heat shock 70kDa protein 1A | -3.29655 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -3.0613 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -3.00845 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -2.98215 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.83402 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | -2.67255 |
| TMEM230 | transmembrane protein 230 | -2.6668 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | -2.56095 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V | -2.50535 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -2.49508 |
| ANXA2 | annexin A2 | -2.49495 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -2.4574 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | -2.40965 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -2.36103 |
| DNAAF5 | dynein, axonemal, assembly factor 5 | -2.33625 |
| RPS5 | ribosomal protein S5 | -2.2773 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | -2.27165 |
| INTS14 | integrator complex subunit 14 | -2.24855 |
| RUFY1 | RUN and FYVE domain containing 1 | -2.2382 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -2.2356 |
| THADA | thyroid adenoma associated | -2.20753 |
| SH3BP4 | SH3-domain binding protein 4 | -2.12255 |
| ACP5 | acid phosphatase 5, tartrate resistant | -2.11735 |
| PLAUR | plasminogen activator, urokinase receptor | -2.10022 |
| RPAP1 | RNA polymerase II associated protein 1 | -2.08955 |
| KRTAP5-2 | keratin associated protein 5-2 | -2.08495 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | -2.0794 |
| STAB2 | stabilin 2 | -2.071 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) | -2.06235 |
| FN3KRP | fructosamine 3 kinase related protein | -2.05745 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -2.0547 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -2.04685 |
| PANK2 | pantothenate kinase 2 | -2.03585 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 | -2.03555 |
| TRIP12 | thyroid hormone receptor interactor 12 | -2.03505 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -2.0343 |
| PSENEN | presenilin enhancer gamma secretase subunit | -2.01555 |
| MTPAP | mitochondrial poly(A) polymerase | -2.01445 |
| PLAC8 | placenta-specific 8 | -2.01085 |
