CRCGN015_MCF10A.TP53.M_24H:D02 Gene Set
Genes
36 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABHD4
|
abhydrolase domain containing 4
|
4.28502
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
4.11742
|
|
MAP7
|
microtubule-associated protein 7
|
4.02498
|
|
RSF1
|
remodeling and spacing factor 1
|
3.39909
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
3.30605
|
|
ALG8
|
ALG8, alpha-1,3-glucosyltransferase
|
3.01255
|
|
CCNA1
|
cyclin A1
|
2.85266
|
|
MMP1
|
matrix metallopeptidase 1
|
2.84276
|
|
AAMDC
|
adipogenesis associated, Mth938 domain containing
|
2.56593
|
|
PKN1
|
protein kinase N1
|
2.55642
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
2.48577
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.43691
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
2.29699
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
2.26845
|
|
PMAIP1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
2.20547
|
|
CSNK1A1
|
casein kinase 1, alpha 1
|
2.2037
|
|
MUC1
|
mucin 1, cell surface associated
|
2.20041
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.02775
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-4.21928
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.13987
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-3.88342
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-3.52531
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-3.32394
|
|
ANXA2
|
annexin A2
|
-3.09004
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.9365
|
|
ATF5
|
activating transcription factor 5
|
-2.88353
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.85849
|
|
THAP11
|
THAP domain containing 11
|
-2.66443
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-2.5381
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.50516
|
|
ATG3
|
autophagy related 3
|
-2.34281
|
|
CETN2
|
centrin, EF-hand protein, 2
|
-2.17866
|
|
ZFP36
|
ZFP36 ring finger protein
|
-2.15869
|
|
CDC50A
|
cell division cycle 50 P4-ATPase accessory subunit A
|
-2.15514
|
|
PIK3R4
|
phosphoinositide-3-kinase, regulatory subunit 4
|
-2.06981
|
|
FOSL1
|
FOS-like antigen 1
|
-2.05417
|
