| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fm550 perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL39L | ribosomal protein L39-like | 6.6477 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 4.12694 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.96674 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.79009 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.44191 |
| MAMLD1 | mastermind-like domain containing 1 | 3.36486 |
| NISCH | nischarin | 3.3346 |
| CDCA4 | cell division cycle associated 4 | 3.29299 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.20336 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.16749 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.06429 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.9972 |
| SNX11 | sorting nexin 11 | 2.82399 |
| VGLL4 | vestigial-like family member 4 | 2.72373 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.70531 |
| NRBF2 | nuclear receptor binding factor 2 | 2.63628 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.61419 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.59648 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.57526 |
| CENPE | centromere protein E, 312kDa | 2.46836 |
| HOXD11 | homeobox D11 | 2.4511 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.41095 |
| S100A4 | S100 calcium binding protein A4 | 2.39834 |
| SPA17 | sperm autoantigenic protein 17 | 2.37003 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | 2.3429 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.3255 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 2.22488 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | 2.18591 |
| CHGB | chromogranin B | 2.12694 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like | 2.09172 |
| ISOC2 | isochorismatase domain containing 2 | 2.0589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRIP1 | nuclear receptor interacting protein 1 | -4.64836 |
| BAG3 | BCL2-associated athanogene 3 | -3.65921 |
| HOXA5 | homeobox A5 | -3.54254 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.11882 |
| GRN | granulin | -3.02572 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.98541 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.89674 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.7464 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.74028 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.67584 |
| SLC35F2 | solute carrier family 35, member F2 | -2.63855 |
| TUBB6 | tubulin, beta 6 class V | -2.5925 |
| TES | testin LIM domain protein | -2.52091 |
| TCEA2 | transcription elongation factor A (SII), 2 | -2.46266 |
| TOR1A | torsin family 1, member A (torsin A) | -2.38516 |
| AMOTL2 | angiomotin like 2 | -2.37789 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.35574 |
| MSMO1 | methylsterol monooxygenase 1 | -2.30664 |
| ZNF318 | zinc finger protein 318 | -2.28417 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -2.26138 |
| RRM2 | ribonucleotide reductase M2 | -2.24402 |
| CHMP5 | charged multivesicular body protein 5 | -2.06351 |
| NOTCH4 | notch 4 | -2.05927 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -2.05152 |
| PALM | paralemmin | -2.02168 |
| SLAMF7 | SLAM family member 7 | -2.0163 |
| COQ4 | coenzyme Q4 | -2.0119 |
| RNF208 | ring finger protein 208 | -2.01045 |
