CRCGN015_MCF10A.TP53.M_24H:D05 Gene Set
Genes
39 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.00542
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.76454
|
|
AGR2
|
anterior gradient 2
|
3.72449
|
|
E2F2
|
E2F transcription factor 2
|
3.72128
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.59248
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
3.23792
|
|
PRKCH
|
protein kinase C, eta
|
2.94799
|
|
LGMN
|
legumain
|
2.5187
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
2.45558
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
2.41661
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.39407
|
|
AP5M1
|
adaptor-related protein complex 5, mu 1 subunit
|
2.37159
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.33279
|
|
SLC35A3
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
|
2.27182
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.21608
|
|
LAGE3
|
L antigen family, member 3
|
2.21346
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.13128
|
|
DPH2
|
DPH2 homolog (S. cerevisiae)
|
2.11013
|
|
HOXA5
|
homeobox A5
|
2.06581
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
2.03015
|
|
MDM4
|
MDM4, p53 regulator
|
2.01181
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HAT1
|
histone acetyltransferase 1
|
-6.22452
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-4.63352
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-4.07575
|
|
COTL1
|
coactosin-like F-actin binding protein 1
|
-4.02456
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.92732
|
|
DSG2
|
desmoglein 2
|
-3.59036
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-3.25209
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.19833
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.80662
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
-2.74323
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.45575
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-2.32016
|
|
FBN1
|
fibrillin 1
|
-2.20444
|
|
RAD51C
|
RAD51 paralog C
|
-2.17168
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-2.15983
|
|
RPA3
|
replication protein A3, 14kDa
|
-2.13041
|
|
ITGAL
|
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
|
-2.09159
|
|
RHOG
|
ras homolog family member G
|
-2.0124
|