CRCGN015_MCF10A.TP53.M_24H:D07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 99.96 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

30 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.38455
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.94415
GET1 guided entry of tail-anchored proteins factor 1 4.0875
IGHMBP2 immunoglobulin mu binding protein 2 3.7487
CENPE centromere protein E, 312kDa 2.99175
MAP2K5 mitogen-activated protein kinase kinase 5 2.73267
SATB1 SATB homeobox 1 2.59895
CCNA1 cyclin A1 2.5512
SQOR sulfide quinone oxidoreductase 2.0731
MELK maternal embryonic leucine zipper kinase 2.0256

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.9742
PCNA proliferating cell nuclear antigen -4.38165
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.35125
VDAC1 voltage-dependent anion channel 1 -4.1232
NVL nuclear VCP-like -3.0976
TMEM230 transmembrane protein 230 -2.8093
COTL1 coactosin-like F-actin binding protein 1 -2.69295
NGRN neugrin, neurite outgrowth associated -2.62715
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.4679
PANK2 pantothenate kinase 2 -2.40435
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.39465
PRSS23 protease, serine, 23 -2.3905
FBXO28 F-box protein 28 -2.30508
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.25625
STXBP2 syntaxin binding protein 2 -2.19505
PIH1D1 PIH1 domain containing 1 -2.15035
NXT1 nuclear transport factor 2-like export factor 1 -2.12675
MAVS mitochondrial antiviral signaling protein -2.06945
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.05645
RBBP9 retinoblastoma binding protein 9 -2.04545