CRCGN015_MCF10A.TP53.M_24H:D08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 5.1988
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.85135
KDM5A lysine (K)-specific demethylase 5A 3.96185
CNRIP1 cannabinoid receptor interacting protein 1 2.9293
SMIM40 small integral membrane protein 40 2.8415
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.63335
AGR2 anterior gradient 2 2.33575
SATB1 SATB homeobox 1 2.23695
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.1313
DPH2 DPH2 homolog (S. cerevisiae) 2.0933
LYRM1 LYR motif containing 1 2.0136

decreased expression

Symbol Name Standardized Value
HEATR1 HEAT repeat containing 1 -4.47615
MLEC malectin -2.87298
BASP1 brain abundant, membrane attached signal protein 1 -2.62975
THAP11 THAP domain containing 11 -2.45825
RPS5 ribosomal protein S5 -2.19895
CTSD cathepsin D -2.1292
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.0052