| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dinitrotoluene 11.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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96 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 5.6089 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 5.331 |
| AGR2 | anterior gradient 2 | 5.0 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.69015 |
| KDM5D | lysine (K)-specific demethylase 5D | 4.6318 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.45995 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 3.63848 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.57978 |
| PRKCH | protein kinase C, eta | 3.39652 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 3.37567 |
| TRIM13 | tripartite motif containing 13 | 3.1361 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.9666 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.96265 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.81205 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 | 2.55555 |
| STMN2 | stathmin 2 | 2.48857 |
| BEX2 | brain expressed X-linked 2 | 2.4474 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.43535 |
| FAM222B | family with sequence similarity 222, member B | 2.4082 |
| HOOK1 | hook microtubule-tethering protein 1 | 2.28655 |
| SYN1 | synapsin I | 2.2442 |
| SDF2 | stromal cell-derived factor 2 | 2.2017 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 2.1917 |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 | 2.1865 |
| NPY | neuropeptide Y | 2.18355 |
| TLCD3A | TLC domain containing 3A | 2.17775 |
| VSNL1 | visinin-like 1 | 2.16995 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 2.167 |
| PLCB4 | phospholipase C, beta 4 | 2.15135 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 2.1453 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 2.1298 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | 2.12115 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | 2.09775 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 2.09765 |
| MED27 | mediator complex subunit 27 | 2.09407 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 2.08845 |
| ZFY | zinc finger protein, Y-linked | 2.08365 |
| PMF1-BGLAP | PMF1-BGLAP readthrough | 2.0816 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 2.0778 |
| NELL1 | NEL-like 1 (chicken) | 2.0612 |
| FRG1 | FSHD region gene 1 | 2.0555 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 2.0407 |
| AUP1 | ancient ubiquitous protein 1 | 2.03705 |
| CRYM | crystallin, mu | 2.03065 |
| EMC8 | ER membrane protein complex subunit 8 | 2.02025 |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | 2.01975 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | 2.00865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -6.7972 |
| LDHD | lactate dehydrogenase D | -5.1849 |
| VAT1 | vesicle amine transport 1 | -5.06245 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -4.73145 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -4.56955 |
| COTL1 | coactosin-like F-actin binding protein 1 | -4.54145 |
| HSPA8 | heat shock 70kDa protein 8 | -4.49608 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.83228 |
| SMC1A | structural maintenance of chromosomes 1A | -3.62178 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -3.515 |
| KDM5C | lysine (K)-specific demethylase 5C | -3.41305 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.14267 |
| COG5 | component of oligomeric golgi complex 5 | -3.08693 |
| RRM2 | ribonucleotide reductase M2 | -2.87538 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -2.85317 |
| S100A7 | S100 calcium binding protein A7 | -2.77705 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | -2.6572 |
| TMEM164 | transmembrane protein 164 | -2.61935 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -2.6002 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -2.47625 |
| ZWINT | ZW10 interacting kinetochore protein | -2.40295 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -2.39055 |
| RBM28 | RNA binding motif protein 28 | -2.3247 |
| LYPD3 | LY6/PLAUR domain containing 3 | -2.2826 |
| STK17B | serine/threonine kinase 17b | -2.26353 |
| SDCBP | syndecan binding protein (syntenin) | -2.2588 |
| PRRX1 | paired related homeobox 1 | -2.2112 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.20124 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -2.19595 |
| GAS2 | growth arrest-specific 2 | -2.19455 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -2.18195 |
| FKBP1C | FK506 binding protein 1C | -2.17675 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | -2.15587 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | -2.11907 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.11525 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -2.1092 |
| BSG | basigin (Ok blood group) | -2.0918 |
| KDM6A | lysine (K)-specific demethylase 6A | -2.09002 |
| RRAGD | Ras-related GTP binding D | -2.08605 |
| CALML5 | calmodulin-like 5 | -2.0748 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | -2.06012 |
| RAD51C | RAD51 paralog C | -2.05815 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -2.0475 |
| SYNPO2L | synaptopodin 2-like | -2.0314 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -2.02305 |
| COL6A1 | collagen, type VI, alpha 1 | -2.02287 |
| LAMC3 | laminin, gamma 3 | -2.022 |
| ATP5PB | ATP synthase peripheral stalk-membrane subunit b | -2.01935 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.0187 |
