| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | metronidazole 34.5 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCP110 | centriolar coiled coil protein 110kDa | 5.0 |
| AGR2 | anterior gradient 2 | 4.96965 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 4.95365 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.46852 |
| E2F2 | E2F transcription factor 2 | 3.88015 |
| HBB | hemoglobin, beta | 3.64843 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.54033 |
| HBA1 | hemoglobin, alpha 1 | 3.40892 |
| TLCD3A | TLC domain containing 3A | 3.07025 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 2.98073 |
| COMP | cartilage oligomeric matrix protein | 2.9067 |
| SP3 | Sp3 transcription factor | 2.74965 |
| REV1 | REV1, polymerase (DNA directed) | 2.71215 |
| CDT1 | chromatin licensing and DNA replication factor 1 | 2.68145 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.61565 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 2.6014 |
| TMEM131L | transmembrane 131 like | 2.5429 |
| GLI2 | GLI family zinc finger 2 | 2.42883 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 2.406 |
| UFSP2 | UFM1-specific peptidase 2 | 2.38975 |
| MEN1 | multiple endocrine neoplasia I | 2.37255 |
| RNF111 | ring finger protein 111 | 2.3237 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 2.3161 |
| EFNA4 | ephrin-A4 | 2.31225 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.29765 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 2.29515 |
| SQOR | sulfide quinone oxidoreductase | 2.2427 |
| CBR4 | carbonyl reductase 4 | 2.2383 |
| EAPP | E2F-associated phosphoprotein | 2.1802 |
| ZNF239 | zinc finger protein 239 | 2.1769 |
| MED28 | mediator complex subunit 28 | 2.16875 |
| METTL4 | methyltransferase like 4 | 2.15705 |
| EXPH5 | exophilin 5 | 2.1495 |
| RSBN1 | round spermatid basic protein 1 | 2.1409 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | 2.13125 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 2.1147 |
| EDN1 | endothelin 1 | 2.09265 |
| NREP | neuronal regeneration related protein | 2.0407 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 2.0365 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 2.02625 |
| AARSD1 | alanyl-tRNA synthetase domain containing 1 | 2.0183 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.017 |
| CENPC | centromere protein C | 2.00545 |
| MMP1 | matrix metallopeptidase 1 | 2.005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COG7 | component of oligomeric golgi complex 7 | -5.2813 |
| RNF167 | ring finger protein 167 | -4.88025 |
| BAG3 | BCL2-associated athanogene 3 | -4.81145 |
| CCNB1 | cyclin B1 | -4.6908 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -4.2325 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -4.06308 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | -3.39 |
| RBM34 | RNA binding motif protein 34 | -3.25032 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -3.2367 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.1555 |
| ANKRD10 | ankyrin repeat domain 10 | -3.14555 |
| GZMM | granzyme M (lymphocyte met-ase 1) | -2.7958 |
| CERT1 | ceramide transporter 1 | -2.55425 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -2.52582 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -2.38265 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 | -2.3228 |
| CORO1C | coronin, actin binding protein, 1C | -2.3099 |
| POLL | polymerase (DNA directed), lambda | -2.28865 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | -2.2361 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -2.22285 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.20345 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -2.19465 |
| DCTN5 | dynactin 5 (p25) | -2.16372 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.1631 |
| TBKBP1 | TBK1 binding protein 1 | -2.1541 |
| NCKAP1L | NCK-associated protein 1-like | -2.11112 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -2.09905 |
| SQSTM1 | sequestosome 1 | -2.09667 |
| NOP2 | NOP2 nucleolar protein | -2.0403 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | -2.0395 |
| PRR13 | proline rich 13 | -2.0093 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -2.0001 |
