CRCGN015_MCF10A.TP53.M_24H:D12 Gene Set
Genes
55 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CNPY3
|
canopy FGF signaling regulator 3
|
5.01965
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.61365
|
|
APBB2
|
amyloid beta (A4) precursor protein-binding, family B, member 2
|
3.81913
|
|
CCNF
|
cyclin F
|
3.80647
|
|
AGR2
|
anterior gradient 2
|
3.75255
|
|
FYN
|
FYN proto-oncogene, Src family tyrosine kinase
|
3.58027
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.4831
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
3.45435
|
|
TBC1D31
|
TBC1 domain family, member 31
|
3.0892
|
|
WIF1
|
WNT inhibitory factor 1
|
2.98385
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
2.9256
|
|
CERK
|
ceramide kinase
|
2.69795
|
|
UGT2B28
|
UDP glucuronosyltransferase 2 family, polypeptide B28
|
2.3444
|
|
CCDC91
|
coiled-coil domain containing 91
|
2.1985
|
|
RNF38
|
ring finger protein 38
|
2.16445
|
|
KYAT1
|
kynurenine aminotransferase 1
|
2.15875
|
|
RCBTB1
|
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
|
2.14005
|
|
ASXL2
|
additional sex combs like transcriptional regulator 2
|
2.1122
|
|
PEX2
|
peroxisomal biogenesis factor 2
|
2.1018
|
|
WDR7
|
WD repeat domain 7
|
2.1006
|
|
FAM50B
|
family with sequence similarity 50, member B
|
2.08305
|
|
PHF21A
|
PHD finger protein 21A
|
2.06965
|
|
RBMS3
|
RNA binding motif, single stranded interacting protein 3
|
2.04885
|
|
DYNC1LI1
|
dynein, cytoplasmic 1, light intermediate chain 1
|
2.0406
|
|
MDN1
|
MDN1, midasin homolog (yeast)
|
2.02725
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.02325
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PMM2
|
phosphomannomutase 2
|
-5.67655
|
|
RNF167
|
ring finger protein 167
|
-5.45985
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-5.26702
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-5.0867
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.72065
|
|
HMG20B
|
high mobility group 20B
|
-4.59352
|
|
CDC45
|
cell division cycle 45
|
-4.42445
|
|
UQCR10
|
ubiquinol-cytochrome c reductase, complex III subunit X
|
-3.8763
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-3.7235
|
|
EXOSC4
|
exosome component 4
|
-3.35355
|
|
TUBA4A
|
tubulin, alpha 4a
|
-3.3209
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.27326
|
|
PDXDC1
|
pyridoxal-dependent decarboxylase domain containing 1
|
-2.6366
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-2.48018
|
|
PRDX4
|
peroxiredoxin 4
|
-2.4793
|
|
TMEM186
|
transmembrane protein 186
|
-2.41045
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.3285
|
|
SHARPIN
|
SHANK-associated RH domain interactor
|
-2.27495
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.27065
|
|
TCEAL9
|
transcription elongation factor A like 9
|
-2.2558
|
|
GRN
|
granulin
|
-2.25558
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.2349
|
|
RPS6KB2
|
ribosomal protein S6 kinase, 70kDa, polypeptide 2
|
-2.2152
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.2146
|
|
PRKAB1
|
protein kinase, AMP-activated, beta 1 non-catalytic subunit
|
-2.15375
|
|
CAPN2
|
calpain 2, (m/II) large subunit
|
-2.14373
|
|
TMEM255A
|
transmembrane protein 255A
|
-2.1319
|
|
RAD51C
|
RAD51 paralog C
|
-2.06497
|
|
BCL7C
|
B-cell CLL/lymphoma 7C
|
-2.0076
|
