| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-butyl chloride 102.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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43 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FKBP14 | FK506 binding protein 14, 22 kDa | 5.49965 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.3412 |
| WIF1 | WNT inhibitory factor 1 | 4.2743 |
| HBA1 | hemoglobin, alpha 1 | 3.4539 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.22417 |
| SCG3 | secretogranin III | 3.1699 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 2.8339 |
| RABEPK | Rab9 effector protein with kelch motifs | 2.57255 |
| STMN4 | stathmin-like 4 | 2.5552 |
| MOK | MOK protein kinase | 2.51355 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.357 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 2.3473 |
| COPS7A | COP9 signalosome subunit 7A | 2.3235 |
| NKX2-2 | NK2 homeobox 2 | 2.2674 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.23985 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 2.1701 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 2.05115 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.04585 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 2.03777 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 2.0366 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.029 |
| CPZ | carboxypeptidase Z | 2.0012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SGK1 | serum/glucocorticoid regulated kinase 1 | -5.7673 |
| TCTA | T-cell leukemia translocation altered | -5.1778 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -5.17625 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -5.055 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -4.84685 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.7424 |
| PUF60 | poly-U binding splicing factor 60KDa | -4.68365 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -2.7391 |
| MRPL30 | mitochondrial ribosomal protein L30 | -2.71145 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.69064 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.57352 |
| SCRIB | scribbled planar cell polarity protein | -2.46945 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | -2.36055 |
| RHOT2 | ras homolog family member T2 | -2.32865 |
| NGRN | neugrin, neurite outgrowth associated | -2.30875 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -2.3077 |
| THAP11 | THAP domain containing 11 | -2.2684 |
| ATP11B | ATPase, class VI, type 11B | -2.1133 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -2.1013 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -2.05585 |
| TUBA4A | tubulin, alpha 4a | -2.0104 |