CRCGN015_MCF10A.TP53.M_24H:D17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-butyl chloride 34.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

737 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TLR4 toll-like receptor 4 10.0
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 10.0
GATA3 GATA binding protein 3 8.10137
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 7.61135
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 6.27773
GASK1B golgi associated kinase 1B 5.955
SRC SRC proto-oncogene, non-receptor tyrosine kinase 5.9251
TES testin LIM domain protein 5.82455
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 5.3686
WIF1 WNT inhibitory factor 1 5.3605
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 5.0467
PLA2G15 phospholipase A2, group XV 4.9366
TLR8 toll-like receptor 8 4.8854
DAND5 DAN domain family member 5, BMP antagonist 4.7578
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 4.652
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 4.6473
CAVIN2 caveolae associated protein 2 4.5754
FPR2 formyl peptide receptor 2 4.47855
PTPRJ protein tyrosine phosphatase, receptor type, J 4.4708
DENND2D DENN/MADD domain containing 2D 4.4121
PLA2G2D phospholipase A2, group IID 4.304
UTRN utrophin 4.2864
SRPX sushi-repeat containing protein, X-linked 4.2844
IL33 interleukin 33 4.28
C5AR1 complement component 5a receptor 1 4.2762
PTPN14 protein tyrosine phosphatase, non-receptor type 14 4.2748
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 4.237
PDCD1LG2 programmed cell death 1 ligand 2 4.2308
TLCD3A TLC domain containing 3A 4.2153
ALAS1 5'-aminolevulinate synthase 1 4.2076
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 4.0944
MCTP1 multiple C2 domains, transmembrane 1 4.085
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 4.0257
HIPK3 homeodomain interacting protein kinase 3 4.0254
CALCRL calcitonin receptor-like 4.0085
FABP4 fatty acid binding protein 4, adipocyte 3.9732
CORO7-PAM16 CORO7-PAM16 readthrough 3.9473
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 3.9276
FKBP5 FK506 binding protein 5 3.9151
BTN1A1 butyrophilin, subfamily 1, member A1 3.8974
GIMAP6 GTPase, IMAP family member 6 3.8919
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.84765
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 3.8475
MELK maternal embryonic leucine zipper kinase 3.7748
TMEM94 transmembrane protein 94 3.7492
GRB7 growth factor receptor-bound protein 7 3.7442
RNFT1-DT RNFT1 divergent transcript 3.729
C3AR1 complement component 3a receptor 1 3.7105
MARCHF1 membrane associated ring-CH-type finger 1 3.6592
THBS1 thrombospondin 1 3.64922
FOXJ3 forkhead box J3 3.64095
C1QB complement component 1, q subcomponent, B chain 3.6243
GIMAP4 GTPase, IMAP family member 4 3.6083
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 3.605
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 3.6039
TLR1 toll-like receptor 1 3.527
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 3.5039
TGFBR1 transforming growth factor, beta receptor 1 3.4783
CLDN18 claudin 18 3.47603
TFCP2 transcription factor CP2 3.466
ALOX15B arachidonate 15-lipoxygenase, type B 3.43
DCBLD2 discoidin, CUB and LCCL domain containing 2 3.3983
MTMR14 myotubularin related protein 14 3.386
PRRX1 paired related homeobox 1 3.3645
MYCT1 myc target 1 3.3629
C1QA complement component 1, q subcomponent, A chain 3.3296
NFIB nuclear factor I/B 3.30781
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 3.3009
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 3.2958
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 3.2823
FPR1 formyl peptide receptor 1 3.2787
SNAP23 synaptosomal-associated protein, 23kDa 3.25607
GGT5 gamma-glutamyltransferase 5 3.2455
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 3.2368
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 3.2339
CPA4 carboxypeptidase A4 3.217
SH3BP1 SH3-domain binding protein 1 3.2038
ENG endoglin 3.19985
FN1 fibronectin 1 3.19065
ATG7 autophagy related 7 3.1834
UBE2D1 ubiquitin-conjugating enzyme E2D 1 3.16175
APOL1 apolipoprotein L, 1 3.1616
TLR5 toll-like receptor 5 3.1439
KIF15 kinesin family member 15 3.1416
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 3.1397
IGSF6 immunoglobulin superfamily, member 6 3.1375
AMPD1 adenosine monophosphate deaminase 1 3.1147
MANSC1 MANSC domain containing 1 3.1057
GTF2B general transcription factor IIB 3.1027
PVR poliovirus receptor 3.09748
FPR3 formyl peptide receptor 3 3.0876
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 3.0777
MAN2B2 mannosidase, alpha, class 2B, member 2 3.0715
VWF von Willebrand factor 3.0708
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 3.06523
VSIG4 V-set and immunoglobulin domain containing 4 3.0636
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 3.062
TLR2 toll-like receptor 2 3.0392
CD302 CD302 molecule 3.0375
ADAMDEC1 ADAM-like, decysin 1 3.0367
VEGFD vascular endothelial growth factor D 3.0352
LMAN1 lectin, mannose-binding, 1 3.0283
DPYD dihydropyrimidine dehydrogenase 3.0254
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 3.0248
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.01717
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 3.00038
ADAM17 ADAM metallopeptidase domain 17 2.99703
CXCR6 chemokine (C-X-C motif) receptor 6 2.99665
MERTK MER proto-oncogene, tyrosine kinase 2.99655
EXOSC5 exosome component 5 2.9663
GNA13 guanine nucleotide binding protein (G protein), alpha 13 2.9663
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.9661
GBP1 guanylate binding protein 1, interferon-inducible 2.9539
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.95253
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.9245
ADORA3 adenosine A3 receptor 2.9218
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.9076
COL8A1 collagen, type VIII, alpha 1 2.90745
CCL14 chemokine (C-C motif) ligand 14 2.9049
MTX2 metaxin 2 2.9004
ZEB2 zinc finger E-box binding homeobox 2 2.8967
NLRP1 NLR family, pyrin domain containing 1 2.89633
CCR2 chemokine (C-C motif) receptor 2 2.8912
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.8908
UBA3 ubiquitin-like modifier activating enzyme 3 2.8871
CCR1 chemokine (C-C motif) receptor 1 2.88
KCTD20 potassium channel tetramerization domain containing 20 2.8795
STX11 syntaxin 11 2.8793
CCL13 chemokine (C-C motif) ligand 13 2.8756
ELL2 elongation factor, RNA polymerase II, 2 2.8613
KANK1 KN motif and ankyrin repeat domains 1 2.8609
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.85215
MAP3K7CL MAP3K7 C-terminal like 2.8518
RBMS3 RNA binding motif, single stranded interacting protein 3 2.8329
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2.82873
PBX1 pre-B-cell leukemia homeobox 1 2.8232
EPAS1 endothelial PAS domain protein 1 2.82085
CRELD2 cysteine-rich with EGF-like domains 2 2.8198
CLEC4A C-type lectin domain family 4, member A 2.8145
EMCN endomucin 2.8108
ARID4B AT rich interactive domain 4B (RBP1-like) 2.7981
COPS5 COP9 signalosome subunit 5 2.7961
CCL8 chemokine (C-C motif) ligand 8 2.7955
CCNE2 cyclin E2 2.7931
CXCR2 chemokine (C-X-C motif) receptor 2 2.792
ACE angiotensin I converting enzyme 2.7898
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.78155
ERBIN erbb2 interacting protein 2.7806
F13A1 coagulation factor XIII, A1 polypeptide 2.774
PDGFC platelet derived growth factor C 2.7703
CAPN7 calpain 7 2.76875
STRN4 striatin, calmodulin binding protein 4 2.7673
TCN2 transcobalamin II 2.767
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 2.7589
AQP9 aquaporin 9 2.7583
GPRC5B G protein-coupled receptor, class C, group 5, member B 2.7521
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 2.75
APOL3 apolipoprotein L, 3 2.7489
AGPS alkylglycerone phosphate synthase 2.7458
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 2.74
FAM3C family with sequence similarity 3, member C 2.7315
UNC13D unc-13 homolog D (C. elegans) 2.7243
BOLA2B bolA family member 2B 2.7185
COL17A1 collagen, type XVII, alpha 1 2.7113
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.6997
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.6947
CCDC6 coiled-coil domain containing 6 2.693
CLEC7A C-type lectin domain family 7, member A 2.6915
ZNF134 zinc finger protein 134 2.6875
GZMK granzyme K (granzyme 3; tryptase II) 2.6873
ADAM15 ADAM metallopeptidase domain 15 2.6812
TPST1 tyrosylprotein sulfotransferase 1 2.6708
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.66805
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.6657
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 2.6565
TMED5 transmembrane emp24 protein transport domain containing 5 2.65625
PLSCR4 phospholipid scramblase 4 2.6517
TBC1D31 TBC1 domain family, member 31 2.6503
TOR4A torsin family 4, member A 2.6459
BMAL2 basic helix-loop-helix ARNT like 2 2.6412
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.6376
TFEC transcription factor EC 2.6348
CMKLR1 chemerin chemokine-like receptor 1 2.6343
SLC38A6 solute carrier family 38, member 6 2.6339
CCDC91 coiled-coil domain containing 91 2.6258
LGALS4 lectin, galactoside-binding, soluble, 4 2.6218
AOAH acyloxyacyl hydrolase (neutrophil) 2.6183
MEOX1 mesenchyme homeobox 1 2.6124
TSPAN8 tetraspanin 8 2.6113
SAMHD1 SAM domain and HD domain 1 2.6107
SMYD2 SET and MYND domain containing 2 2.6094
ATAD2 ATPase family, AAA domain containing 2 2.6042
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 2.601
DOCK4 dedicator of cytokinesis 4 2.5987
TCAP titin-cap 2.5932
LALBA lactalbumin, alpha- 2.5888
RAB5A RAB5A, member RAS oncogene family 2.5877
SIRPA signal-regulatory protein alpha 2.57893
SLTM SAFB-like, transcription modulator 2.57754
NOTCH2 notch 2 2.57622
CD36 CD36 molecule (thrombospondin receptor) 2.573
SIRPG signal-regulatory protein gamma 2.5728
MCL1 myeloid cell leukemia 1 2.5607
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2.55885
SRI sorcin 2.5552
TSG101 tumor susceptibility 101 2.554
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 2.5524
KCTD12 potassium channel tetramerization domain containing 12 2.55175
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 2.5497
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 2.5411
ALCAM activated leukocyte cell adhesion molecule 2.5406
MNDA myeloid cell nuclear differentiation antigen 2.5376
ADRA2A adrenoceptor alpha 2A 2.5368
LOC124900388 uncharacterized LOC124900388 2.5363
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 2.53365
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.53
MSR1 macrophage scavenger receptor 1 2.5261
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 2.5255
IL1R1 interleukin 1 receptor, type I 2.51645
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 2.5155
SAMD9 sterile alpha motif domain containing 9 2.5144
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 2.513
BMP6 bone morphogenetic protein 6 2.5129
ADIPOQ adiponectin, C1Q and collagen domain containing 2.5085
TENM1 teneurin transmembrane protein 1 2.5059
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 2.4996
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.4986
KLF5 Kruppel-like factor 5 (intestinal) 2.4971
ZNF227 zinc finger protein 227 2.4954
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 2.4925
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.4913
TRIM49D2 tripartite motif containing 49D2 2.4872
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.48
IL1R2 interleukin 1 receptor, type II 2.4775
CTSS cathepsin S 2.4771
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.477
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 2.4642
EPS15 epidermal growth factor receptor pathway substrate 15 2.4641
RHOBTB2 Rho-related BTB domain containing 2 2.462
HPSE heparanase 2.4615
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2.45577
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.4502
MDFIC MyoD family inhibitor domain containing 2.44925
IFRD1 interferon-related developmental regulator 1 2.44845
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 2.4443
PARN poly(A)-specific ribonuclease 2.4431
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 2.4393
FGF7 fibroblast growth factor 7 2.4391
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.4379
RYR3 ryanodine receptor 3 2.4369
ASCC2 activating signal cointegrator 1 complex subunit 2 2.4356
FOXRED2 FAD-dependent oxidoreductase domain containing 2 2.4355
PLXNC1 plexin C1 2.43543
ECHDC1 ethylmalonyl-CoA decarboxylase 1 2.435
IRX5 iroquois homeobox 5 2.431
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.4293
CYB561D2 cytochrome b561 family, member D2 2.4239
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.4237
LRP1B low density lipoprotein receptor-related protein 1B 2.415
ADPRH ADP-ribosylarginine hydrolase 2.4137
FFAR2 free fatty acid receptor 2 2.4115
MAP4 microtubule-associated protein 4 2.4107
SYNM synemin, intermediate filament protein 2.4089
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.4069
CCL24 chemokine (C-C motif) ligand 24 2.4031
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.3977
MMRN2 multimerin 2 2.3968
PTPRM protein tyrosine phosphatase, receptor type, M 2.3958
CCL19 chemokine (C-C motif) ligand 19 2.3952
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.3949
RAB20 RAB20, member RAS oncogene family 2.392
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 2.39023
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 2.3872
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.3871
TRAK1 trafficking protein, kinesin binding 1 2.37795
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.3749
OMD osteomodulin 2.3741
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.3705
ABHD14A abhydrolase domain containing 14A 2.366
SSBP1 single-stranded DNA binding protein 1, mitochondrial 2.3646
CNGB3 cyclic nucleotide gated channel beta 3 2.3638
NABP1 nucleic acid binding protein 1 2.3544
EVI2B ecotropic viral integration site 2B 2.3527
HSPG2 heparan sulfate proteoglycan 2 2.3514
CEP170 centrosomal protein 170kDa 2.35035
LCAT lecithin-cholesterol acyltransferase 2.3478
PTPRB protein tyrosine phosphatase, receptor type, B 2.34675
ACSL5 acyl-CoA synthetase long-chain family member 5 2.3456
NAP1L3 nucleosome assembly protein 1-like 3 2.3385
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.33705
OMG oligodendrocyte myelin glycoprotein 2.3355
ABR active BCR-related 2.33215
LPIN1 lipin 1 2.3295
UBASH3A ubiquitin associated and SH3 domain containing A 2.3272
TMOD3 tropomodulin 3 (ubiquitous) 2.3248
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.321
TGM2 transglutaminase 2 2.31818
VEGFC vascular endothelial growth factor C 2.3178
LPL lipoprotein lipase 2.31685
LYZ lysozyme 2.3162
DYSF dysferlin 2.3104
MARCKS myristoylated alanine-rich protein kinase C substrate 2.309
EXOC5 exocyst complex component 5 2.3088
DPT dermatopontin 2.30833
SGPP1 sphingosine-1-phosphate phosphatase 1 2.3077
CFHR2 complement factor H-related 2 2.3076
XPO6 exportin 6 2.3039
EML4 echinoderm microtubule associated protein like 4 2.3018
ATP13A2 ATPase type 13A2 2.2994
RGS18 regulator of G-protein signaling 18 2.2966
AHR aryl hydrocarbon receptor 2.2961
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.294
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.2935
TM4SF1 transmembrane 4 L six family member 1 2.29198
DHRS3 dehydrogenase/reductase (SDR family) member 3 2.2911
CANT1 calcium activated nucleotidase 1 2.2897
STARD3 StAR-related lipid transfer (START) domain containing 3 2.288
SLAMF1 signaling lymphocytic activation molecule family member 1 2.2833
FOXC2 forkhead box C2 2.2775
FBXO46 F-box protein 46 2.2738
CD46 CD46 molecule, complement regulatory protein 2.26997
SS18 synovial sarcoma translocation, chromosome 18 2.26973
PLCG1 phospholipase C, gamma 1 2.26725
FBN1 fibrillin 1 2.26625
EPS8 epidermal growth factor receptor pathway substrate 8 2.2639
LOC124904395 uncharacterized LOC124904395 2.26379
TLR6 toll-like receptor 6 2.2633
ACSL1 acyl-CoA synthetase long-chain family member 1 2.2629
FCAR Fc fragment of IgA receptor 2.26055
CD180 CD180 molecule 2.2589
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.2586
KYAT3 kynurenine aminotransferase 3 2.2575
LEPROT leptin receptor overlapping transcript 2.25707
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 2.2567
EMP1 epithelial membrane protein 1 2.2556
KCTD7 potassium channel tetramerization domain containing 7 2.2509
ANKRD55 ankyrin repeat domain 55 2.2496
KLHL21 kelch-like family member 21 2.2495
FZD6 frizzled class receptor 6 2.2407
STARD8 StAR-related lipid transfer (START) domain containing 8 2.2347
AZIN2 antizyme inhibitor 2 2.2345
SPAST spastin 2.2326
ARC activity-regulated cytoskeleton-associated protein 2.2324
AOX1 aldehyde oxidase 1 2.23215
CD163 CD163 molecule 2.2313
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 2.2304
LIMK2 LIM domain kinase 2 2.22917
CCR3 chemokine (C-C motif) receptor 3 2.227
FAT4 FAT atypical cadherin 4 2.2262
SCYL2 SCY1-like 2 (S. cerevisiae) 2.2242
PHTF2 putative homeodomain transcription factor 2 2.22263
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 2.221
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 2.2204
GMPR2 guanosine monophosphate reductase 2 2.2186
MRC1 mannose receptor, C type 1 2.2141
PLXNA2 plexin A2 2.21345
PARP1 poly (ADP-ribose) polymerase 1 2.2133
RTCA RNA 3'-terminal phosphate cyclase 2.2126
MTMR3 myotubularin related protein 3 2.21247
CPB1 carboxypeptidase B1 (tissue) 2.2068
STX5 syntaxin 5 2.2044
CD209 CD209 molecule 2.19945
TPM3 tropomyosin 3 2.1986
GCA grancalcin, EF-hand calcium binding protein 2.1966
SLAMF8 SLAM family member 8 2.19485
MGAM maltase-glucoamylase 2.1912
NOTCH4 notch 4 2.1911
ABLIM3 actin binding LIM protein family, member 3 2.1909
EXOC1 exocyst complex component 1 2.1885
PTAFR platelet-activating factor receptor 2.1883
SAP30BP SAP30 binding protein 2.188
EDAR ectodysplasin A receptor 2.1863
ANPEP alanyl (membrane) aminopeptidase 2.184
UST uronyl-2-sulfotransferase 2.18295
RGS7 regulator of G-protein signaling 7 2.1812
PM20D1 peptidase M20 domain containing 1 2.18055
IL17RA interleukin 17 receptor A 2.1796
SNN stannin 2.17775
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.1776
RPE ribulose-5-phosphate-3-epimerase 2.1766
POGK pogo transposable element with KRAB domain 2.1746
ANXA10 annexin A10 2.1739
MYH1 myosin, heavy chain 1, skeletal muscle, adult 2.1722
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 2.171
DUSP28 dual specificity phosphatase 28 2.168
PXDC1 PX domain containing 1 2.1675
ACTN3 actinin, alpha 3 (gene/pseudogene) 2.1585
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.1576
ESRP2 epithelial splicing regulatory protein 2 2.1573
NADK NAD kinase 2.1567
HOXA2 homeobox A2 2.1532
NCAN neurocan 2.1501
ZNF480 zinc finger protein 480 2.1483
AHCTF1 AT hook containing transcription factor 1 2.1479
SLC38A12 solute carrier family 38 member 12 2.142
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.1418
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.1354
PGC progastricsin (pepsinogen C) 2.1348
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like 2.1334
MFAP5 microfibrillar associated protein 5 2.13197
LXN latexin 2.1306
MYOZ2 myozenin 2 2.1279
B3GAT3 beta-1,3-glucuronyltransferase 3 2.12595
SPAG16 sperm associated antigen 16 2.121
SLFN12 schlafen family member 12 2.121
WIPF1 WAS/WASL interacting protein family, member 1 2.12073
NEK2 NIMA-related kinase 2 2.11715
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.1168
TRIM25 tripartite motif containing 25 2.1133
NEK9 NIMA-related kinase 9 2.1113
TACC2 transforming, acidic coiled-coil containing protein 2 2.1098
TMEM164 transmembrane protein 164 2.1083
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 2.1082
TRPS1 trichorhinophalangeal syndrome I 2.1075
LY96 lymphocyte antigen 96 2.1074
ACTN2 actinin, alpha 2 2.10617
AOC3 amine oxidase, copper containing 3 2.1061
EDNRB endothelin receptor type B 2.1011
TPSAB1 tryptase alpha/beta 1 2.0926
RNGTT RNA guanylyltransferase and 5'-phosphatase 2.0925
MMRN1 multimerin 1 2.0924
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.0909
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.0889
ASTN1 astrotactin 1 2.0886
ECSIT ECSIT signalling integrator 2.0886
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2.0883
MYOG myogenin (myogenic factor 4) 2.0879
TRDN triadin 2.0831
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 2.0814
APOL6 apolipoprotein L, 6 2.0777
TPM1 tropomyosin 1 (alpha) 2.07297
NBAS neuroblastoma amplified sequence 2.0692
FNDC4 fibronectin type III domain containing 4 2.068
GP6 glycoprotein VI (platelet) 2.0677
BHLHE41 basic helix-loop-helix family, member e41 2.0636
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.0631
DUOX1 dual oxidase 1 2.06275
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 2.05975
RASA3 RAS p21 protein activator 3 2.05965
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B 2.0526
MAP3K6 mitogen-activated protein kinase kinase kinase 6 2.0514
LZTFL1 leucine zipper transcription factor-like 1 2.048
MYBPC1 myosin binding protein C, slow type 2.0457
NID1 nidogen 1 2.04495
ERC1 ELKS/RAB6-interacting/CAST family member 1 2.0437
CCNF cyclin F 2.0432
SLC39A7 solute carrier family 39 (zinc transporter), member 7 2.0423
PDE7B phosphodiesterase 7B 2.04
RRAS related RAS viral (r-ras) oncogene homolog 2.0394
DPYSL2 dihydropyrimidinase-like 2 2.0387
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.0328
ANKRD44 ankyrin repeat domain 44 2.0304
SCAP SREBF chaperone 2.0298
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.0277
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.0262
PALMD palmdelphin 2.0259
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.0233
CSN1S1 casein alpha s1 2.0211
STX3 syntaxin 3 2.0197
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 2.0155
NMRK1 nicotinamide riboside kinase 1 2.0124
NTM neurotrimin 2.0108
EXOC2 exocyst complex component 2 2.01
GIMAP5 GTPase, IMAP family member 5 2.0073
PHIP pleckstrin homology domain interacting protein 2.00695
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 2.0042
OSMR oncostatin M receptor 2.0023
TMEM100 transmembrane protein 100 2.0022
IFI44L interferon-induced protein 44-like 2.0019
CISH cytokine inducible SH2-containing protein 2.0015

decreased expression

Symbol Name Standardized Value
PGAM4 phosphoglycerate mutase family member 4 -10.0
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -10.0
PRPF4 pre-mRNA processing factor 4 -9.26725
CD81 CD81 molecule -7.7684
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -5.7457
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -5.1231
BSPRY B-box and SPRY domain containing -4.471
NR4A2 nuclear receptor subfamily 4, group A, member 2 -4.3649
SLC31A1 solute carrier family 31 (copper transporter), member 1 -4.2223
TP53 tumor protein p53 -4.15095
LINC02762 long intergenic non-protein coding RNA 2762 -4.13865
WBP1L WW domain binding protein 1-like -4.0658
COTL1 coactosin-like F-actin binding protein 1 -3.9974
CAPZB capping protein (actin filament) muscle Z-line, beta -3.90193
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -3.8587
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -3.7427
ASCC1 activating signal cointegrator 1 complex subunit 1 -3.6783
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.6583
BDKRB2 bradykinin receptor B2 -3.6244
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -3.4394
SIGLEC15 sialic acid binding Ig-like lectin 15 -3.3479
XPA xeroderma pigmentosum, complementation group A -3.3438
TDRD7 tudor domain containing 7 -3.3399
ANXA6 annexin A6 -3.2393
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -3.2161
SPON2 spondin 2, extracellular matrix protein -3.2124
CDK8 cyclin-dependent kinase 8 -3.1858
PELO pelota homolog (Drosophila) -3.1846
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -3.1659
YJU2B YJU2 splicing factor homolog B -3.1628
GHITM growth hormone inducible transmembrane protein -3.1546
RAB8A RAB8A, member RAS oncogene family -3.1468
LITAF lipopolysaccharide-induced TNF factor -3.14405
MXRA7 matrix-remodelling associated 7 -3.0749
ZMYM2 zinc finger, MYM-type 2 -3.06697
ZNF506 zinc finger protein 506 -3.0568
BDKRB1 bradykinin receptor B1 -3.0188
ARHGAP4 Rho GTPase activating protein 4 -3.0171
RABL3 RAB, member of RAS oncogene family-like 3 -2.9661
PFN1 profilin 1 -2.9637
CAPN2 calpain 2, (m/II) large subunit -2.9381
CENPS-CORT CENPS-CORT readthrough -2.9268
KIAA0232 KIAA0232 -2.9176
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.8951
CLDN4 claudin 4 -2.8811
KLK1 kallikrein 1 -2.8799
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -2.8782
PGK1 phosphoglycerate kinase 1 -2.8472
ZDHHC4 zinc finger, DHHC-type containing 4 -2.8468
GCHFR GTP cyclohydrolase I feedback regulator -2.8421
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -2.8368
VCPKMT valosin containing protein lysine (K) methyltransferase -2.8353
TMEM265 transmembrane protein 265 -2.827
PKM pyruvate kinase, muscle -2.8269
FNBP1 formin binding protein 1 -2.82575
GRID1 glutamate receptor, ionotropic, delta 1 -2.8161
THOC1 THO complex 1 -2.8145
AGO1 argonaute RISC catalytic component 1 -2.8144
SFXN3 sideroflexin 3 -2.8091
CD37 CD37 molecule -2.7875
ASS1 argininosuccinate synthase 1 -2.7761
PPCDC phosphopantothenoylcysteine decarboxylase -2.7637
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.7632
RHOF ras homolog family member F (in filopodia) -2.7606
SCAF11 SR-related CTD-associated factor 11 -2.74787
SNX3 sorting nexin 3 -2.7424
MTPAP mitochondrial poly(A) polymerase -2.7383
ALAD aminolevulinate dehydratase -2.7329
NINJ2 ninjurin 2 -2.7204
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -2.7152
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -2.7037
PTEN phosphatase and tensin homolog -2.69473
DENND1A DENN/MADD domain containing 1A -2.6919
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.6898
IL23A interleukin 23, alpha subunit p19 -2.6865
PARL presenilin associated, rhomboid-like -2.6813
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.6796
SPRY4 sprouty homolog 4 (Drosophila) -2.6764
DNTT DNA nucleotidylexotransferase -2.6632
ROGDI rogdi homolog (Drosophila) -2.6541
LEFTY2 left-right determination factor 2 -2.652
ARMCX6 armadillo repeat containing, X-linked 6 -2.6305
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -2.6218
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.6159
LTC4S leukotriene C4 synthase -2.6086
FBXW4 F-box and WD repeat domain containing 4 -2.6054
CTSW cathepsin W -2.5905
CRY1 cryptochrome circadian clock 1 -2.577
RPA3 replication protein A3, 14kDa -2.5716
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.57105
SIK2 salt-inducible kinase 2 -2.57
SMIM7 small integral membrane protein 7 -2.5609
H2BC5 H2B clustered histone 5 -2.5501
TCTN3 tectonic family member 3 -2.53645
AVPI1 arginine vasopressin-induced 1 -2.5353
ZNF331 zinc finger protein 331 -2.532
MED7 mediator complex subunit 7 -2.52545
DUSP14 dual specificity phosphatase 14 -2.5227
MSRB1 methionine sulfoxide reductase B1 -2.5225
MSRB2 methionine sulfoxide reductase B2 -2.5208
H2AC19 H2A clustered histone 19 -2.5153
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.514
CENPT centromere protein T -2.504
ENO1 enolase 1, (alpha) -2.50155
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -2.49815
CS citrate synthase -2.498
LRRC42 leucine rich repeat containing 42 -2.487
TGDS TDP-glucose 4,6-dehydratase -2.4822
MRPL57 mitochondrial ribosomal protein L57 -2.4788
TMEM106C transmembrane protein 106C -2.4755
CKB creatine kinase, brain -2.4734
CD248 CD248 molecule, endosialin -2.4707
NEUROG1 neurogenin 1 -2.4674
CCS copper chaperone for superoxide dismutase -2.4672
ILK integrin-linked kinase -2.466
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.4546
NOPCHAP1 NOP protein chaperone 1 -2.4534
TOR1AIP2 torsin A interacting protein 2 -2.4527
EIF3E eukaryotic translation initiation factor 3, subunit E -2.4409
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.4406
MTCH1 mitochondrial carrier 1 -2.4371
CCL22 chemokine (C-C motif) ligand 22 -2.4325
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.42965
MPHOSPH9 M-phase phosphoprotein 9 -2.41987
COL6A2 collagen, type VI, alpha 2 -2.41255
TMEM51 transmembrane protein 51 -2.4122
SNAI1 snail family zinc finger 1 -2.4091
RBM12B RNA binding motif protein 12B -2.4046
FAM149A family with sequence similarity 149, member A -2.4027
TUBA4A tubulin, alpha 4a -2.381
OGDHL oxoglutarate dehydrogenase-like -2.3717
PRR13 proline rich 13 -2.3699
DENND2B DENN domain containing 2B -2.36
TESK2 testis-specific kinase 2 -2.351
TK1 thymidine kinase 1, soluble -2.3363
QPRT quinolinate phosphoribosyltransferase -2.3339
CLEC11A C-type lectin domain family 11, member A -2.33033
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.3099
LARP1 La ribonucleoprotein domain family, member 1 -2.3067
BCORL1 BCL6 corepressor-like 1 -2.3039
IL3RA interleukin 3 receptor, alpha (low affinity) -2.3034
SNED1 sushi, nidogen and EGF-like domains 1 -2.2956
SEPHS1 selenophosphate synthetase 1 -2.29347
GLRX5 glutaredoxin 5 -2.2927
KLHDC4 kelch domain containing 4 -2.2925
MSRA methionine sulfoxide reductase A -2.2915
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -2.2901
CRABP2 cellular retinoic acid binding protein 2 -2.288
UQCRB ubiquinol-cytochrome c reductase binding protein -2.2874
MBD5 methyl-CpG binding domain protein 5 -2.2772
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.2718
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -2.2681
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -2.2623
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.2609
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.26
GRM4 glutamate receptor, metabotropic 4 -2.256
HILPDA hypoxia inducible lipid droplet-associated -2.2559
ZNF248 zinc finger protein 248 -2.2353
CNOT9 CCR4-NOT transcription complex subunit 9 -2.22985
CTSA cathepsin A -2.2182
TOR1B torsin family 1, member B (torsin B) -2.2167
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.2167
KRT16 keratin 16, type I -2.2164
GPRC5C G protein-coupled receptor, class C, group 5, member C -2.2161
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.2161
NRIP3 nuclear receptor interacting protein 3 -2.2109
AK8 adenylate kinase 8 -2.2102
ZBTB24 zinc finger and BTB domain containing 24 -2.2021
BRD9 bromodomain containing 9 -2.2012
RAB11FIP5 RAB11 family interacting protein 5 (class I) -2.1963
HLA-G major histocompatibility complex, class I, G -2.19622
ANAPC2 anaphase promoting complex subunit 2 -2.1953
CLCNKA chloride channel, voltage-sensitive Ka -2.1937
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1935
ASPHD1 aspartate beta-hydroxylase domain containing 1 -2.1922
KCNK5 potassium channel, two pore domain subfamily K, member 5 -2.1919
GLO1 glyoxalase I -2.1843
TMEM106B transmembrane protein 106B -2.1829
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -2.17995
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.17645
NCKIPSD NCK interacting protein with SH3 domain -2.1737
LOC102724428 serine/threonine-protein kinase SIK1 -2.1725
PRKCQ protein kinase C, theta -2.16475
CYB5R3 cytochrome b5 reductase 3 -2.1622
CAPNS1 calpain, small subunit 1 -2.1617
IGFBP5 insulin-like growth factor binding protein 5 -2.15604
NELFCD negative elongation factor complex member C/D -2.154
REEP1 receptor accessory protein 1 -2.14715
NPTN neuroplastin -2.1435
GSE1 Gse1 coiled-coil protein -2.1429
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.1428
BCL2L13 BCL2-like 13 (apoptosis facilitator) -2.1384
FXYD6-FXYD2 FXYD6-FXYD2 readthrough -2.1375
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.1375
XKR8 XK, Kell blood group complex subunit-related family, member 8 -2.1354
PDZD8 PDZ domain containing 8 -2.1337
TERF2 telomeric repeat binding factor 2 -2.1319
CNGA1 cyclic nucleotide gated channel alpha 1 -2.1313
SOD3 superoxide dismutase 3, extracellular -2.1303
RIOK2 RIO kinase 2 -2.129
CREM cAMP responsive element modulator -2.129
GOLM1 golgi membrane protein 1 -2.1275
CXCL8 chemokine (C-X-C motif) ligand 8 -2.1273
ARHGAP32 Rho GTPase activating protein 32 -2.127
SYNDIG1 synapse differentiation inducing 1 -2.1251
OXR1 oxidation resistance 1 -2.1223
TLE2 transducin-like enhancer of split 2 -2.1201
RETREG2 reticulophagy regulator family member 2 -2.118
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -2.11665
FMNL1 formin-like 1 -2.1134
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.1131
LCMT2 leucine carboxyl methyltransferase 2 -2.1105
XAB2 XPA binding protein 2 -2.11
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.10965
FLT3 fms-related tyrosine kinase 3 -2.1075
MMP13 matrix metallopeptidase 13 -2.1055
SIPA1 signal-induced proliferation-associated 1 -2.1018
HMBOX1 homeobox containing 1 -2.1006
IL2RG interleukin 2 receptor, gamma -2.0996
WHRN whirlin -2.09945
DDAH2 dimethylarginine dimethylaminohydrolase 2 -2.09923
UNC119B unc-119 homolog B (C. elegans) -2.098
KLHDC8A kelch domain containing 8A -2.0956
RPN2 ribophorin II -2.09327
MRS2 MRS2 magnesium transporter -2.09275
ZBTB25 zinc finger and BTB domain containing 25 -2.0921
PANX1 pannexin 1 -2.091
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.0883
ARF3 ADP-ribosylation factor 3 -2.08643
BANP BTG3 associated nuclear protein -2.0802
PARP16 poly (ADP-ribose) polymerase family, member 16 -2.0781
TPI1 triosephosphate isomerase 1 -2.07187
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.0718
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -2.0707
ENO2 enolase 2 (gamma, neuronal) -2.0705
ZBED1 zinc finger, BED-type containing 1 -2.0685
ZNF146 zinc finger protein 146 -2.0663
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.059
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.05835
TRIM8 tripartite motif containing 8 -2.0579
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -2.0499
RUNX3 runt-related transcription factor 3 -2.0476
RC3H2 ring finger and CCCH-type domains 2 -2.04695
MRPL42 mitochondrial ribosomal protein L42 -2.045
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 -2.0422
TGM1 transglutaminase 1 -2.0365
MATN4 matrilin 4 -2.0256
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.02535
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.02493
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.0238
ZNF562 zinc finger protein 562 -2.0233
EPHX3 epoxide hydrolase 3 -2.023
PRCP prolylcarboxypeptidase (angiotensinase C) -2.0221
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.0215
THNSL2 threonine synthase-like 2 (S. cerevisiae) -2.0192
FXYD2 FXYD domain containing ion transport regulator 2 -2.0187
TBL1X transducin (beta)-like 1X-linked -2.01832
THY1 Thy-1 cell surface antigen -2.0143
SSBP3 single stranded DNA binding protein 3 -2.0138
SH2D1A SH2 domain containing 1A -2.01155
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -2.0103
RBM38 RNA binding motif protein 38 -2.0091
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0086
DUSP5 dual specificity phosphatase 5 -2.0056
PDS5B PDS5 cohesin associated factor B -2.00227
HINT1 histidine triad nucleotide binding protein 1 -2.0008
TCP11L1 t-complex 11, testis-specific-like 1 -2.00015