CRCGN015_MCF10A.TP53.M_24H:D19 Gene Set
Genes
15 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
3.7096
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
2.8124
|
|
MMP1
|
matrix metallopeptidase 1
|
2.41735
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.22745
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.0613
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-4.38065
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
-4.3017
|
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3
|
-3.49755
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
-3.16135
|
|
INTS3
|
integrator complex subunit 3
|
-2.52075
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.45565
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.2813
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
-2.2395
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
-2.20885
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.0895
|
