CRCGN015_MCF10A.TP53.M_24H:D21 Gene Set
Genes
51 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SSBP2
|
single-stranded DNA binding protein 2
|
5.90345
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.20485
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
4.18185
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
3.67815
|
|
FZD7
|
frizzled class receptor 7
|
3.43905
|
|
SIRT3
|
sirtuin 3
|
3.33783
|
|
RAB21
|
RAB21, member RAS oncogene family
|
3.21105
|
|
PLA2G4A
|
phospholipase A2, group IVA (cytosolic, calcium-dependent)
|
2.77475
|
|
GRB7
|
growth factor receptor-bound protein 7
|
2.6828
|
|
CBR4
|
carbonyl reductase 4
|
2.4676
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.36425
|
|
RIC8A
|
RIC8 guanine nucleotide exchange factor A
|
2.3358
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
2.2604
|
|
DEAF1
|
DEAF1 transcription factor
|
2.2353
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.22605
|
|
CCT6B
|
chaperonin containing TCP1, subunit 6B (zeta 2)
|
2.20555
|
|
SLC15A3
|
solute carrier family 15 (oligopeptide transporter), member 3
|
2.155
|
|
ZNF195
|
zinc finger protein 195
|
2.14095
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
2.12775
|
|
STK16
|
serine/threonine kinase 16
|
2.0807
|
|
TKFC
|
triokinase/FMN cyclase
|
2.0796
|
|
CMAS
|
cytidine monophosphate N-acetylneuraminic acid synthetase
|
2.06745
|
|
RRM1
|
ribonucleotide reductase M1
|
2.0569
|
|
TIMM23
|
translocase of inner mitochondrial membrane 23 homolog (yeast)
|
2.03277
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.09935
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-4.8549
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
-4.45065
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-4.3337
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-4.17617
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-3.8646
|
|
PTK2
|
protein tyrosine kinase 2
|
-3.50435
|
|
RPS5
|
ribosomal protein S5
|
-3.1428
|
|
CD320
|
CD320 molecule
|
-3.10515
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-3.0851
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.972
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.9652
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.85455
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
-2.6878
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.52787
|
|
REV3L
|
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
|
-2.4045
|
|
FOXA2
|
forkhead box A2
|
-2.3584
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
-2.352
|
|
MORC4
|
MORC family CW-type zinc finger 4
|
-2.3268
|
|
DYNC1H1
|
dynein, cytoplasmic 1, heavy chain 1
|
-2.2794
|
|
CMTR1
|
cap methyltransferase 1
|
-2.2358
|
|
ABCC2
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
|
-2.17545
|
|
TCHH
|
trichohyalin
|
-2.1062
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.05615
|
|
CRY1
|
cryptochrome circadian clock 1
|
-2.0351
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.01513
|
|
AACS
|
acetoacetyl-CoA synthetase
|
-2.0085
|
