CRCGN015_MCF10A.TP53.M_24H:E01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tin (ii) chloride 99.96 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

19 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:E01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 5.08323
FGFR4 fibroblast growth factor receptor 4 4.29546
MELK maternal embryonic leucine zipper kinase 3.02099
ADAT1 adenosine deaminase, tRNA-specific 1 2.72515
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.63622
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 2.62117
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.59803
MMP1 matrix metallopeptidase 1 2.36337
DOCK6 dedicator of cytokinesis 6 2.2938
PRKCH protein kinase C, eta 2.11369
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.07376
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.0034

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.48765
BASP1 brain abundant, membrane attached signal protein 1 -4.0536
GRN granulin -3.96575
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.92313
HMG20B high mobility group 20B -3.02475
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.31386
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.05675