CRCGN015_MCF10A.TP53.M_24H:E02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tin (ii) chloride 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.16079
GATA2 GATA binding protein 2 2.79309
FZD1 frizzled class receptor 1 2.72793
CETN3 centrin, EF-hand protein, 3 2.14442
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.05494
CHN1 chimerin 1 2.01822

decreased expression

Symbol Name Standardized Value
HEATR1 HEAT repeat containing 1 -6.85026
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -5.51863
CD81 CD81 molecule -3.4006
PCCB propionyl CoA carboxylase, beta polypeptide -2.93186
GGPS1 geranylgeranyl diphosphate synthase 1 -2.87883
DSG2 desmoglein 2 -2.77554
TBCE tubulin folding cofactor E -2.74109
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.74016
RPS5 ribosomal protein S5 -2.68801
CBR3 carbonyl reductase 3 -2.54221
REEP5 receptor accessory protein 5 -2.53643
RBM34 RNA binding motif protein 34 -2.51673
KRT14 keratin 14, type I -2.35311
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.3188
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.29106
GNPAT glyceronephosphate O-acyltransferase -2.11423
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -2.07145
STC2 stanniocalcin 2 -2.02285