CRCGN015_MCF10A.TP53.M_24H:E06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tricresyl phosphate 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:E06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 4.81524
CARMIL1 capping protein regulator and myosin 1 linker 1 4.63882
CXCR4 chemokine (C-X-C motif) receptor 4 4.3239
E2F2 E2F transcription factor 2 4.19313
WDR7 WD repeat domain 7 3.88075
MAMLD1 mastermind-like domain containing 1 3.86934
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.83486
ACAA1 acetyl-CoA acyltransferase 1 3.64899
FGFR4 fibroblast growth factor receptor 4 3.4346
SNAP25 synaptosomal-associated protein, 25kDa 3.16911
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.02664
NOSIP nitric oxide synthase interacting protein 2.79999
PDLIM1 PDZ and LIM domain 1 2.71181
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.68846
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.66582
RBMX2 RNA binding motif protein, X-linked 2 2.65012
COMP cartilage oligomeric matrix protein 2.64681
GJD2 gap junction protein, delta 2, 36kDa 2.39866
DACT1 dishevelled-binding antagonist of beta-catenin 1 2.37166
LRRN3 leucine rich repeat neuronal 3 2.24162
ZIM2 zinc finger, imprinted 2 2.12722
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 2.0725
STAT4 signal transducer and activator of transcription 4 2.06692
TOB1 transducer of ERBB2, 1 2.0386
TBC1D16 TBC1 domain family, member 16 2.00595
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 2.00109

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -4.55209
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.98456
CAB39 calcium binding protein 39 -3.80168
ACOT9 acyl-CoA thioesterase 9 -3.60047
OXA1L oxidase (cytochrome c) assembly 1-like -3.42892
TEX10 testis expressed 10 -3.41424
CCNB1 cyclin B1 -2.68161
KDM3A lysine (K)-specific demethylase 3A -2.29472
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.20475
SNX16 sorting nexin 16 -2.06173
MTFR1 mitochondrial fission regulator 1 -2.04203
NRIP1 nuclear receptor interacting protein 1 -2.02758