| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-methylene-bis(2-methyl?aniline) 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 5.42625 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.7155 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 3.66425 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.5387 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.46795 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.1187 |
| TBX2 | T-box 2 | 3.04658 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.88655 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 2.63885 |
| LETMD1 | LETM1 domain containing 1 | 2.62485 |
| CENPE | centromere protein E, 312kDa | 2.53475 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.471 |
| MRPL19 | mitochondrial ribosomal protein L19 | 2.4131 |
| CHEK2 | checkpoint kinase 2 | 2.4055 |
| EML3 | echinoderm microtubule associated protein like 3 | 2.28492 |
| PRAF2 | PRA1 domain family, member 2 | 2.23855 |
| FPGS | folylpolyglutamate synthase | 2.21225 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 2.16437 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 2.14675 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.11565 |
| BLVRA | biliverdin reductase A | 2.1131 |
| ANXA5 | annexin A5 | 2.10105 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | 2.09385 |
| ACOT8 | acyl-CoA thioesterase 8 | 2.08305 |
| TRAPPC12 | trafficking protein particle complex 12 | 2.0824 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 2.08115 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 2.0752 |
| SNX17 | sorting nexin 17 | 2.0384 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.01155 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 2.00005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRN | granulin | -5.58958 |
| CD58 | CD58 molecule | -5.4062 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.94335 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.76865 |
| CORO1A | coronin, actin binding protein, 1A | -4.2965 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -4.0463 |
| CD320 | CD320 molecule | -3.2349 |
| NGRN | neugrin, neurite outgrowth associated | -2.91 |
| HTRA1 | HtrA serine peptidase 1 | -2.8109 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.7016 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.64035 |
| SDC1 | syndecan 1 | -2.54745 |
| ANGPTL2 | angiopoietin-like 2 | -2.32263 |
| RAI14 | retinoic acid induced 14 | -2.27965 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | -2.2529 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -2.2139 |
| POU2AF1 | POU class 2 associating factor 1 | -2.188 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.17515 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.16078 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -2.1261 |
| C1QL1 | complement component 1, q subcomponent-like 1 | -2.1241 |
| CDHR1 | cadherin-related family member 1 | -2.1209 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -2.08475 |
| CTSD | cathepsin D | -2.07625 |
| LRRK1 | leucine-rich repeat kinase 1 | -2.06235 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -2.0424 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -2.0402 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme | -2.02755 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 | -2.0221 |
| TUBAL3 | tubulin, alpha-like 3 | -2.0046 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor | -2.00235 |
