| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | propyl gallate 11.16 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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68 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 6.9854 |
| NUCB2 | nucleobindin 2 | 5.2654 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 5.2114 |
| FGFR4 | fibroblast growth factor receptor 4 | 4.65452 |
| TXNRD1 | thioredoxin reductase 1 | 4.11725 |
| CAPN1 | calpain 1, (mu/I) large subunit | 3.65575 |
| SNX11 | sorting nexin 11 | 3.59232 |
| NOTCH1 | notch 1 | 3.16215 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.0733 |
| STATH | statherin | 2.7848 |
| SMR3B | submaxillary gland androgen regulated protein 3B | 2.67915 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.56715 |
| PRR15L | proline rich 15-like | 2.5523 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.4537 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.3986 |
| SMR3A | submaxillary gland androgen regulated protein 3A | 2.34635 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 2.33303 |
| WIF1 | WNT inhibitory factor 1 | 2.2838 |
| GLRX | glutaredoxin (thioltransferase) | 2.2724 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | 2.25955 |
| NECTIN4 | nectin cell adhesion molecule 4 | 2.23685 |
| CBX1 | chromobox homolog 1 | 2.2044 |
| RAB27B | RAB27B, member RAS oncogene family | 2.19597 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 2.17985 |
| SAR1B | secretion associated, Ras related GTPase 1B | 2.1473 |
| LPO | lactoperoxidase | 2.10335 |
| APOD | apolipoprotein D | 2.09385 |
| SQSTM1 | sequestosome 1 | 2.08812 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 2.07297 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 2.04075 |
| CYP2F1 | cytochrome P450, family 2, subfamily F, polypeptide 1 | 2.0392 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.01097 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -5.9612 |
| TES | testin LIM domain protein | -5.49222 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.5708 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.51735 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -3.82187 |
| THAP11 | THAP domain containing 11 | -3.7324 |
| STMN1 | stathmin 1 | -3.71375 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.61315 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.09312 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.96877 |
| ITM2C | integral membrane protein 2C | -2.72575 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.68895 |
| AURKB | aurora kinase B | -2.56515 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.51917 |
| MTO1 | mitochondrial tRNA translation optimization 1 | -2.4506 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.4048 |
| FHL2 | four and a half LIM domains 2 | -2.383 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) | -2.34015 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.33308 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.28245 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -2.27645 |
| TMX2 | thioredoxin-related transmembrane protein 2 | -2.27595 |
| TASP1 | taspase, threonine aspartase, 1 | -2.26365 |
| CKAP5 | cytoskeleton associated protein 5 | -2.20155 |
| NCAPH | non-SMC condensin I complex, subunit H | -2.18495 |
| ZNF574 | zinc finger protein 574 | -2.1212 |
| CBR3 | carbonyl reductase 3 | -2.1201 |
| NUP133 | nucleoporin 133kDa | -2.09315 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.09025 |
| AREL1 | apoptosis resistant E3 ubiquitin protein ligase 1 | -2.08695 |
| MOK | MOK protein kinase | -2.0773 |
| EPHA4 | EPH receptor A4 | -2.0659 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -2.04305 |
| STAC | SH3 and cysteine rich domain | -2.03985 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 | -2.02445 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | -2.00355 |