CRCGN015_MCF10A.TP53.M_24H:E21 Gene Set
Genes
48 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.1327
|
|
STXBP1
|
syntaxin binding protein 1
|
5.09725
|
|
E2F2
|
E2F transcription factor 2
|
5.0
|
|
ABHD4
|
abhydrolase domain containing 4
|
4.47635
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
4.3844
|
|
GRB10
|
growth factor receptor-bound protein 10
|
4.02248
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
3.2569
|
|
CCNA1
|
cyclin A1
|
2.8221
|
|
WIF1
|
WNT inhibitory factor 1
|
2.5122
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
2.45805
|
|
NUCB2
|
nucleobindin 2
|
2.38635
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.29577
|
|
GPN2
|
GPN-loop GTPase 2
|
2.28925
|
|
YIPF3
|
Yip1 domain family, member 3
|
2.24175
|
|
PPP6R1
|
protein phosphatase 6, regulatory subunit 1
|
2.2278
|
|
PLEKHG5
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
|
2.21525
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.14337
|
|
TSSC4
|
tumor suppressing subtransferable candidate 4
|
2.1103
|
|
IL21
|
interleukin 21
|
2.0952
|
|
XAB2
|
XPA binding protein 2
|
2.08985
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.0798
|
|
TRMO
|
tRNA methyltransferase O
|
2.06663
|
|
MACIR
|
macrophage immunometabolism regulator
|
2.06105
|
|
SLC25A24
|
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
|
2.02285
|
|
GSTM5
|
glutathione S-transferase mu 5
|
2.01875
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TES
|
testin LIM domain protein
|
-5.68443
|
|
YARS2
|
tyrosyl-tRNA synthetase 2, mitochondrial
|
-5.01555
|
|
CDC25B
|
cell division cycle 25B
|
-5.0
|
|
DNM1L
|
dynamin 1-like
|
-4.9354
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-4.6849
|
|
HMG20B
|
high mobility group 20B
|
-4.30218
|
|
THAP11
|
THAP domain containing 11
|
-3.7368
|
|
ZMYM2
|
zinc finger, MYM-type 2
|
-3.28835
|
|
BID
|
BH3 interacting domain death agonist
|
-3.16652
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-3.1188
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-3.03775
|
|
RAI14
|
retinoic acid induced 14
|
-2.86715
|
|
CAPRIN2
|
caprin family member 2
|
-2.7834
|
|
XPO4
|
exportin 4
|
-2.66135
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.63223
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.43727
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.38485
|
|
IL4R
|
interleukin 4 receptor
|
-2.2778
|
|
SLC22A1
|
solute carrier family 22 (organic cation transporter), member 1
|
-2.0944
|
|
FGL1
|
fibrinogen-like 1
|
-2.0398
|
|
CDK8
|
cyclin-dependent kinase 8
|
-2.02845
|
|
INTS13
|
integrator complex subunit 13
|
-2.02645
|
|
PDIA6
|
protein disulfide isomerase family A, member 6
|
-2.00087
|
