| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diethylstilbestrol 11.16 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNPY3 | canopy FGF signaling regulator 3 | 5.25793 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.69637 |
| STK10 | serine/threonine kinase 10 | 4.67334 |
| RPL39L | ribosomal protein L39-like | 4.44869 |
| MAMLD1 | mastermind-like domain containing 1 | 4.40883 |
| AGR2 | anterior gradient 2 | 4.31023 |
| ZNF586 | zinc finger protein 586 | 3.97506 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.96983 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.38112 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.1537 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.76646 |
| AXIN1 | axin 1 | 2.68486 |
| NOTCH1 | notch 1 | 2.63722 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 2.59661 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 2.54257 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.49458 |
| CEP57 | centrosomal protein 57kDa | 2.48491 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.43084 |
| PYCARD | PYD and CARD domain containing | 2.33582 |
| BMP4 | bone morphogenetic protein 4 | 2.32294 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 2.30984 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.21813 |
| RNASE4 | ribonuclease, RNase A family, 4 | 2.19802 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 2.17812 |
| MORC4 | MORC family CW-type zinc finger 4 | 2.14829 |
| TTC12 | tetratricopeptide repeat domain 12 | 2.12323 |
| LOC124907782 | dual specificity protein phosphatase 22 | 2.1178 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.10878 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) | 2.08502 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.05244 |
| CLEC1A | C-type lectin domain family 1, member A | 2.04426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.90968 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -4.76064 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.41424 |
| LAP3 | leucine aminopeptidase 3 | -4.34761 |
| MSMO1 | methylsterol monooxygenase 1 | -3.26022 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -3.13597 |
| COTL1 | coactosin-like F-actin binding protein 1 | -3.09842 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -3.08502 |
| HMG20B | high mobility group 20B | -2.74812 |
| RBM34 | RNA binding motif protein 34 | -2.69323 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.59183 |
| GNAS | GNAS complex locus | -2.57703 |
| UBE3C | ubiquitin protein ligase E3C | -2.57003 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -2.56781 |
| HSPA8 | heat shock 70kDa protein 8 | -2.53917 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | -2.52121 |
| ATG3 | autophagy related 3 | -2.5007 |
| SMYD3 | SET and MYND domain containing 3 | -2.49544 |
| ATF6 | activating transcription factor 6 | -2.49206 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.43159 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.3453 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.30619 |
| PPA1 | pyrophosphatase (inorganic) 1 | -2.25025 |
| PFN1 | profilin 1 | -2.2441 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -2.20383 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -2.18973 |
| GPM6A | glycoprotein M6A | -2.11022 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -2.10354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -2.07731 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -2.01738 |
