CRCGN015_MCF10A.TP53.M_24H:F04 Gene Set
Genes
27 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EAPP
|
E2F-associated phosphoprotein
|
4.63357
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
4.63018
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.55823
|
|
LGMN
|
legumain
|
3.07196
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.05009
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.93493
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.8883
|
|
SPTSSA
|
serine palmitoyltransferase, small subunit A
|
2.81608
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.67931
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
2.35958
|
|
PSMA6
|
proteasome (prosome, macropain) subunit, alpha type, 6
|
2.3471
|
|
MBIP
|
MAP3K12 binding inhibitory protein 1
|
2.31941
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
2.29442
|
|
SRP54
|
signal recognition particle 54kDa
|
2.2906
|
|
PLA2G4A
|
phospholipase A2, group IVA (cytosolic, calcium-dependent)
|
2.28841
|
|
CADM1
|
cell adhesion molecule 1
|
2.16832
|
|
KCNN2
|
potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
|
2.07763
|
|
ARHGAP5
|
Rho GTPase activating protein 5
|
2.01493
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.97424
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-4.64117
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-3.95588
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.41209
|
|
PIH1D1
|
PIH1 domain containing 1
|
-3.22254
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.96268
|
|
TSPAN3
|
tetraspanin 3
|
-2.73586
|
|
GRN
|
granulin
|
-2.4818
|
|
PIGT
|
phosphatidylinositol glycan anchor biosynthesis, class T
|
-2.05909
|
