CRCGN015_MCF10A.TP53.M_24H:F07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexachlorocyclopentadiene 101.47 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

44 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 5.0885
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.93775
MAP7 microtubule-associated protein 7 4.77825
KLHL21 kelch-like family member 21 4.7675
WIF1 WNT inhibitory factor 1 4.6893
LAGE3 L antigen family, member 3 4.30705
E2F2 E2F transcription factor 2 4.22955
FGFR4 fibroblast growth factor receptor 4 4.11155
ACAA1 acetyl-CoA acyltransferase 1 3.2928
SATB1 SATB homeobox 1 2.705
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.56885
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.48295
ASB9 ankyrin repeat and SOCS box containing 9 2.46675
CLCN5 chloride channel, voltage-sensitive 5 2.41165
RPL10L ribosomal protein L10-like 2.39455
DENND2D DENN/MADD domain containing 2D 2.27915
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 2.2718
CDC25C cell division cycle 25C 2.18235
VCP valosin containing protein 2.15103
FAM3A family with sequence similarity 3, member A 2.1194
MERTK MER proto-oncogene, tyrosine kinase 2.1134
TH tyrosine hydroxylase 2.1006
ATP5F1E ATP synthase F1 subunit epsilon 2.0965
APTX aprataxin 2.04957
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.04635
ITGA9 integrin, alpha 9 2.0254
KANK1 KN motif and ankyrin repeat domains 1 2.01965
PRM2 protamine 2 2.00345

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -6.43165
NPDC1 neural proliferation, differentiation and control, 1 -5.4952
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.82498
CDC20 cell division cycle 20 -4.66275
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.22075
ANKRD10 ankyrin repeat domain 10 -3.03155
CD81 CD81 molecule -2.6546
RGS2 regulator of G-protein signaling 2 -2.5454
DUSP5 dual specificity phosphatase 5 -2.21445
CBY1 chibby homolog 1 (Drosophila) -2.15795
OBI1 ORC ubiquitin ligase 1 -2.1003
RMC1 regulator of MON1-CCZ1 -2.08365
MED8 mediator complex subunit 8 -2.0651
ASTE1 asteroid homolog 1 (Drosophila) -2.03495
TPP2 tripeptidyl peptidase II -2.02958
UEVLD UEV and lactate/malate dehyrogenase domains -2.02785