| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexachlorocyclopentadiene 11.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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95 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 5.10429 |
| SPAG4 | sperm associated antigen 4 | 4.91405 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 4.90139 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.8391 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.7166 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.66275 |
| AXIN1 | axin 1 | 4.5726 |
| KLHL21 | kelch-like family member 21 | 3.4796 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.39705 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 3.0424 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.03275 |
| NOSIP | nitric oxide synthase interacting protein | 2.95675 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.95425 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 2.8151 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 2.81495 |
| EVL | Enah/Vasp-like | 2.76995 |
| TSPAN6 | tetraspanin 6 | 2.73767 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | 2.68625 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.6496 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.3998 |
| CKAP2 | cytoskeleton associated protein 2 | 2.32815 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 2.32375 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 2.2971 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 2.2637 |
| PDCD5 | programmed cell death 5 | 2.21795 |
| NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 2.18395 |
| LUC7L | LUC7-like (S. cerevisiae) | 2.1542 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 2.1157 |
| KIF23 | kinesin family member 23 | 2.10645 |
| SMYD5 | SMYD family member 5 | 2.1023 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 2.0766 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 2.05265 |
| RAD51AP1 | RAD51 associated protein 1 | 2.05145 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 2.04575 |
| HS1BP3 | HCLS1 binding protein 3 | 2.0391 |
| TMEM11 | transmembrane protein 11 | 2.03715 |
| CCDC91 | coiled-coil domain containing 91 | 2.0317 |
| PLTP | phospholipid transfer protein | 2.01325 |
| HBB | hemoglobin, beta | 2.00682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF167 | ring finger protein 167 | -5.40975 |
| PFN1 | profilin 1 | -4.59915 |
| CDC20 | cell division cycle 20 | -4.17075 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -3.82208 |
| CD81 | CD81 molecule | -3.78775 |
| TCTA | T-cell leukemia translocation altered | -3.0383 |
| CPB1 | carboxypeptidase B1 (tissue) | -2.6656 |
| CRABP1 | cellular retinoic acid binding protein 1 | -2.6154 |
| ELOVL1 | ELOVL fatty acid elongase 1 | -2.58605 |
| CCDC15 | coiled-coil domain containing 15 | -2.57365 |
| INF2 | inverted formin, FH2 and WH2 domain containing | -2.5372 |
| LOC124907090 | ankyrin repeat domain-containing protein SOWAHC-like | -2.5357 |
| TNN | tenascin N | -2.41835 |
| SZT2 | seizure threshold 2 homolog (mouse) | -2.41248 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -2.3322 |
| LRRC17 | leucine rich repeat containing 17 | -2.30665 |
| ZNF529 | zinc finger protein 529 | -2.2833 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.2537 |
| TCHH | trichohyalin | -2.25065 |
| SCAF4 | SR-related CTD-associated factor 4 | -2.24878 |
| PLVAP | plasmalemma vesicle associated protein | -2.21835 |
| MAVS | mitochondrial antiviral signaling protein | -2.20115 |
| CD160 | CD160 molecule | -2.19615 |
| RLF | rearranged L-myc fusion | -2.1891 |
| SLC6A16 | solute carrier family 6, member 16 | -2.18545 |
| GATAD2A | GATA zinc finger domain containing 2A | -2.1743 |
| PLK2 | polo-like kinase 2 | -2.166 |
| SEMG1 | semenogelin I | -2.1631 |
| ZBED2 | zinc finger, BED-type containing 2 | -2.15365 |
| APOA1 | apolipoprotein A-I | -2.14815 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -2.1439 |
| SPATA7 | spermatogenesis associated 7 | -2.1417 |
| PDE1B | phosphodiesterase 1B, calmodulin-dependent | -2.1378 |
| PDGFD | platelet derived growth factor D | -2.126 |
| PHF20L1 | PHD finger protein 20-like 1 | -2.11815 |
| PRND | prion protein 2 (dublet) | -2.11205 |
| GSTT1 | glutathione S-transferase theta 1 | -2.09845 |
| HPX | hemopexin | -2.08842 |
| IRF8 | interferon regulatory factor 8 | -2.08045 |
| RAP1A | RAP1A, member of RAS oncogene family | -2.08035 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -2.07465 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.07315 |
| MED8 | mediator complex subunit 8 | -2.06882 |
| SEMG2 | semenogelin II | -2.0629 |
| GFRA1 | GDNF family receptor alpha 1 | -2.06185 |
| TMEM127 | transmembrane protein 127 | -2.0571 |
| DENND1A | DENN/MADD domain containing 1A | -2.05555 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -2.05285 |
| MSTN | myostatin | -2.05095 |
| CISH | cytokine inducible SH2-containing protein | -2.0504 |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 | -2.03315 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -2.0244 |
| TBKBP1 | TBK1 binding protein 1 | -2.0236 |
| CRISP2 | cysteine-rich secretory protein 2 | -2.02205 |
| CRYBA2 | crystallin, beta A2 | -2.0119 |
| APH1A | APH1A gamma secretase subunit | -2.00405 |
