CRCGN015_MCF10A.TP53.M_24H:F11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 5.3732
WFS1 Wolfram syndrome 1 (wolframin) 5.22085
CHMP6 charged multivesicular body protein 6 5.0372
RPL39L ribosomal protein L39-like 4.6121
STK10 serine/threonine kinase 10 4.3016
SPAG4 sperm associated antigen 4 4.2645
KDM5D lysine (K)-specific demethylase 5D 4.108
WASF3 WAS protein family, member 3 4.03325
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.80885
TBX2 T-box 2 3.7462
NOSIP nitric oxide synthase interacting protein 3.14695
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 3.10795
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.98165
USP9Y ubiquitin specific peptidase 9, Y-linked 2.81422
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.6975
SQOR sulfide quinone oxidoreductase 2.68975
EVL Enah/Vasp-like 2.6087
CCNE2 cyclin E2 2.59907
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.4325
PDLIM2 PDZ and LIM domain 2 (mystique) 2.41865
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.41655
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.3401
TLE6 transducin-like enhancer of split 6 2.30015
TRIB3 tribbles pseudokinase 3 2.2508
TMOD1 tropomodulin 1 2.2183
NLGN4Y neuroligin 4, Y-linked 2.2049
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 2.11945
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.09945
ETV4 ets variant 4 2.0562
MCRS1 microspherule protein 1 2.0032

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -4.38005
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -3.8191
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -3.0457
KDM5C lysine (K)-specific demethylase 5C -3.03885
IPO13 importin 13 -3.00725
THAP11 THAP domain containing 11 -2.78705
CORO1A coronin, actin binding protein, 1A -2.5506
EXOSC4 exosome component 4 -2.53005
KDM6A lysine (K)-specific demethylase 6A -2.52145
JMJD6 jumonji domain containing 6 -2.50468
SMC1A structural maintenance of chromosomes 1A -2.47207
UBA1 ubiquitin-like modifier activating enzyme 1 -2.3093
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -2.28035
MTX2 metaxin 2 -2.2206
USP9X ubiquitin specific peptidase 9, X-linked -2.12352
HSPE1 heat shock 10kDa protein 1 -2.11065
HDAC4 histone deacetylase 4 -2.0739
RPS5 ribosomal protein S5 -2.02105