CRCGN015_MCF10A.TP53.M_24H:F12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 11.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 5.2226
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 5.16015
GPER1 G protein-coupled estrogen receptor 1 4.51517
SNX11 sorting nexin 11 4.39468
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.3603
BTK Bruton agammaglobulinemia tyrosine kinase 4.22765
TBX2 T-box 2 3.86777
ACAA1 acetyl-CoA acyltransferase 1 3.7871
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.66465
TP53I3 tumor protein p53 inducible protein 3 2.37405
SF3B5 splicing factor 3b, subunit 5, 10kDa 2.25875
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.1872
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.17895
EPM2AIP1 EPM2A (laforin) interacting protein 1 2.1451
CEP57 centrosomal protein 57kDa 2.13463
MTCH2 mitochondrial carrier 2 2.1088
RPL14 ribosomal protein L14 2.0783
TYK2 tyrosine kinase 2 2.04695
ATP5F1E ATP synthase F1 subunit epsilon 2.033
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 2.0006

decreased expression

Symbol Name Standardized Value
TES testin LIM domain protein -5.4088
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.3746
SCYL3 SCY1-like 3 (S. cerevisiae) -4.92228
CD44 CD44 molecule (Indian blood group) -4.46211
CCNB1 cyclin B1 -4.44115
SGK1 serum/glucocorticoid regulated kinase 1 -3.31805
ANXA2 annexin A2 -2.87405
NGRN neugrin, neurite outgrowth associated -2.642
CAV2 caveolin 2 -2.36623
DSE dermatan sulfate epimerase -2.28745
IL20RA interleukin 20 receptor, alpha -2.26555
IL6 interleukin 6 -2.25945
GSR glutathione reductase -2.19325
SORBS3 sorbin and SH3 domain containing 3 -2.13355
OLFM4 olfactomedin 4 -2.10445
DUSP14 dual specificity phosphatase 14 -2.0219
ZIC3 Zic family member 3 -2.01335