| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzoic acid, sodium 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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103 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 5.66167 |
| AGR2 | anterior gradient 2 | 5.0 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.96413 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 4.58745 |
| CCDC85B | coiled-coil domain containing 85B | 4.43625 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.3762 |
| KIF5C | kinesin family member 5C | 4.30325 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.27723 |
| NUTF2 | nuclear transport factor 2 | 3.36665 |
| HDGFL3 | HDGF like 3 | 3.33857 |
| MTA2 | metastasis associated 1 family, member 2 | 3.1906 |
| WIF1 | WNT inhibitory factor 1 | 3.07615 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.97695 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.76148 |
| STMN2 | stathmin 2 | 2.7465 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.67335 |
| SATB1 | SATB homeobox 1 | 2.6089 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.5566 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | 2.52285 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 2.48335 |
| POU4F1 | POU class 4 homeobox 1 | 2.44668 |
| KIAA0513 | KIAA0513 | 2.43795 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 2.43645 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | 2.43205 |
| NEFM | neurofilament, medium polypeptide | 2.42745 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | 2.40007 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 2.37918 |
| RGS4 | regulator of G-protein signaling 4 | 2.3335 |
| RGS7 | regulator of G-protein signaling 7 | 2.32565 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase | 2.3103 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 2.2829 |
| CHURC1-FNTB | CHURC1-FNTB readthrough | 2.27563 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 2.2614 |
| HMGB2 | high mobility group box 2 | 2.25015 |
| NSF | N-ethylmaleimide-sensitive factor | 2.2314 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 2.223 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 2.21055 |
| VSNL1 | visinin-like 1 | 2.20325 |
| PI15 | peptidase inhibitor 15 | 2.17675 |
| GPSM2 | G-protein signaling modulator 2 | 2.16797 |
| SCD5 | stearoyl-CoA desaturase 5 | 2.16275 |
| SPACA9 | sperm acrosome associated 9 | 2.1541 |
| NEFL | neurofilament, light polypeptide | 2.15333 |
| PTPRS | protein tyrosine phosphatase, receptor type, S | 2.1201 |
| GDF7 | growth differentiation factor 7 | 2.12 |
| SMAGP | small cell adhesion glycoprotein | 2.1158 |
| OSGEP | O-sialoglycoprotein endopeptidase | 2.1085 |
| DGKD | diacylglycerol kinase, delta 130kDa | 2.09335 |
| AGTR1 | angiotensin II receptor, type 1 | 2.09008 |
| HOXB9 | homeobox B9 | 2.06595 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 2.06205 |
| DCTN4 | dynactin 4 (p62) | 2.05195 |
| KCNK7 | potassium channel, two pore domain subfamily K, member 7 | 2.0167 |
| WDR5B | WD repeat domain 5B | 2.0139 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACOT9 | acyl-CoA thioesterase 9 | -5.4925 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -5.1388 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -4.85642 |
| KIF14 | kinesin family member 14 | -4.7892 |
| COTL1 | coactosin-like F-actin binding protein 1 | -4.5793 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.54175 |
| HEATR1 | HEAT repeat containing 1 | -4.5057 |
| HSPA8 | heat shock 70kDa protein 8 | -4.45425 |
| CD44 | CD44 molecule (Indian blood group) | -4.35135 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.26745 |
| HMG20B | high mobility group 20B | -4.15707 |
| LYPLA1 | lysophospholipase I | -3.76585 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.6422 |
| CD81 | CD81 molecule | -3.40095 |
| ANKRD10 | ankyrin repeat domain 10 | -2.7908 |
| COL7A1 | collagen, type VII, alpha 1 | -2.55095 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -2.51615 |
| MAGT1 | magnesium transporter 1 | -2.44965 |
| PRDX4 | peroxiredoxin 4 | -2.4076 |
| SH2B2 | SH2B adaptor protein 2 | -2.3991 |
| IL7R | interleukin 7 receptor | -2.36145 |
| SLAMF7 | SLAM family member 7 | -2.3487 |
| INPP5K | inositol polyphosphate-5-phosphatase K | -2.32643 |
| CNPY3 | canopy FGF signaling regulator 3 | -2.2858 |
| MICB | MHC class I polypeptide-related sequence B | -2.2753 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -2.24485 |
| CEP170 | centrosomal protein 170kDa | -2.23315 |
| KRT14 | keratin 14, type I | -2.21065 |
| GSDME | gasdermin E | -2.2096 |
| RTL8A | retrotransposon Gag like 8A | -2.17365 |
| NES | nestin | -2.16305 |
| POU2AF1 | POU class 2 associating factor 1 | -2.1395 |
| WTAP | Wilms tumor 1 associated protein | -2.13895 |
| TNIP3 | TNFAIP3 interacting protein 3 | -2.1238 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -2.0935 |
| ACOT2 | acyl-CoA thioesterase 2 | -2.0917 |
| KLF13 | Kruppel-like factor 13 | -2.08425 |
| ARSA | arylsulfatase A | -2.08315 |
| BEX3 | brain expressed X-linked 3 | -2.0801 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -2.06155 |
| PITPNA | phosphatidylinositol transfer protein, alpha | -2.06042 |
| EBI3 | Epstein-Barr virus induced 3 | -2.0389 |
| OGFRL1 | opioid growth factor receptor-like 1 | -2.0323 |
| CLIC2 | chloride intracellular channel 2 | -2.02575 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -2.0249 |
| SPON2 | spondin 2, extracellular matrix protein | -2.01975 |
| ARHGAP22 | Rho GTPase activating protein 22 | -2.0195 |
| TNS2 | tensin 2 | -2.0101 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | -2.0016 |