CRCGN015_MCF10A.TP53.M_24H:F18 Gene Set
Genes
59 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.20855
|
|
CCDC92
|
coiled-coil domain containing 92
|
5.90995
|
|
TXNRD1
|
thioredoxin reductase 1
|
5.527
|
|
MEF2C
|
myocyte enhancer factor 2C
|
5.04225
|
|
FZD1
|
frizzled class receptor 1
|
4.32725
|
|
TBX2
|
T-box 2
|
4.23727
|
|
GRB10
|
growth factor receptor-bound protein 10
|
3.98637
|
|
HMGA2
|
high mobility group AT-hook 2
|
3.31965
|
|
WIF1
|
WNT inhibitory factor 1
|
3.3037
|
|
HDGFL3
|
HDGF like 3
|
3.20881
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
3.20292
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
3.1183
|
|
FOSL1
|
FOS-like antigen 1
|
3.0156
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
2.93765
|
|
FHL2
|
four and a half LIM domains 2
|
2.748
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.5583
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
2.53405
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
2.42695
|
|
PALM2AKAP2
|
PALM2 and AKAP2 fusion
|
2.3204
|
|
VEGFC
|
vascular endothelial growth factor C
|
2.3071
|
|
BET1
|
Bet1 golgi vesicular membrane trafficking protein
|
2.1778
|
|
UCHL1
|
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
|
2.15425
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
2.13215
|
|
CD34
|
CD34 molecule
|
2.09075
|
|
HMOX1
|
heme oxygenase 1
|
2.0906
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
2.0864
|
|
ABCA6
|
ATP-binding cassette, sub-family A (ABC1), member 6
|
2.08315
|
|
NETO2
|
neuropilin (NRP) and tolloid (TLL)-like 2
|
2.00965
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ENOPH1
|
enolase-phosphatase 1
|
-5.1024
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-4.5327
|
|
COG7
|
component of oligomeric golgi complex 7
|
-4.03615
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-3.49835
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
-3.22725
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-3.02027
|
|
RAD51C
|
RAD51 paralog C
|
-2.95553
|
|
PRR15L
|
proline rich 15-like
|
-2.8181
|
|
CD320
|
CD320 molecule
|
-2.7612
|
|
CLEC16A
|
C-type lectin domain family 16, member A
|
-2.7553
|
|
SMPDL3B
|
sphingomyelin phosphodiesterase, acid-like 3B
|
-2.69015
|
|
UBXN2B
|
UBX domain protein 2B
|
-2.5656
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.53295
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
-2.47505
|
|
SYBU
|
syntabulin (syntaxin-interacting)
|
-2.3757
|
|
STAP2
|
signal transducing adaptor family member 2
|
-2.357
|
|
HBE1
|
hemoglobin, epsilon 1
|
-2.33265
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
-2.3067
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.30515
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.2936
|
|
LITAF
|
lipopolysaccharide-induced TNF factor
|
-2.26735
|
|
ASCL1
|
achaete-scute family bHLH transcription factor 1
|
-2.26455
|
|
SDAD1
|
SDA1 domain containing 1
|
-2.1853
|
|
LOC102724652
|
alpha-crystallin A chain
|
-2.16125
|
|
SIPA1
|
signal-induced proliferation-associated 1
|
-2.1237
|
|
NBEAL2
|
neurobeachin-like 2
|
-2.1
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.08935
|
|
PPT1
|
palmitoyl-protein thioesterase 1
|
-2.07885
|
|
CELSR2
|
cadherin, EGF LAG seven-pass G-type receptor 2
|
-2.07013
|
|
DNAJC12
|
DnaJ (Hsp40) homolog, subfamily C, member 12
|
-2.0098
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.0081
|
