CRCGN015_MCF10A.TP53.M_24H:F19 Gene Set
Genes
46 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDCA4
|
cell division cycle associated 4
|
5.6131
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
5.0
|
|
VGLL4
|
vestigial-like family member 4
|
3.89803
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
3.59183
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.57913
|
|
WIF1
|
WNT inhibitory factor 1
|
3.50815
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
3.4715
|
|
TBPL1
|
TBP-like 1
|
3.3495
|
|
IGFBP3
|
insulin-like growth factor binding protein 3
|
3.20377
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
2.61925
|
|
HMGA2
|
high mobility group AT-hook 2
|
2.61235
|
|
MAT2A
|
methionine adenosyltransferase II, alpha
|
2.47108
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
2.4382
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.2916
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
2.24919
|
|
TLCD3A
|
TLC domain containing 3A
|
2.14615
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.08845
|
|
IL1B
|
interleukin 1, beta
|
2.01552
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-5.33725
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.2041
|
|
CDC25B
|
cell division cycle 25B
|
-4.93755
|
|
HMG20B
|
high mobility group 20B
|
-4.25632
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.6571
|
|
TUBA4A
|
tubulin, alpha 4a
|
-3.4308
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.3987
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-3.2852
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-3.05418
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.99005
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.9338
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.92725
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
-2.45075
|
|
FBXO3
|
F-box protein 3
|
-2.37285
|
|
PSMB5
|
proteasome (prosome, macropain) subunit, beta type, 5
|
-2.3485
|
|
SCN1B
|
sodium channel, voltage gated, type I beta subunit
|
-2.34675
|
|
PRR15L
|
proline rich 15-like
|
-2.32135
|
|
COMMD9
|
COMM domain containing 9
|
-2.26105
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
-2.2028
|
|
NAXD
|
NAD(P)HX dehydratase
|
-2.16405
|
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3
|
-2.16365
|
|
IPCEF1
|
interaction protein for cytohesin exchange factors 1
|
-2.1612
|
|
METTL17
|
methyltransferase like 17
|
-2.1177
|
|
NSF
|
N-ethylmaleimide-sensitive factor
|
-2.11465
|
|
NEMF
|
nuclear export mediator factor
|
-2.11215
|
|
SNTA1
|
syntrophin, alpha 1
|
-2.10385
|
|
AACS
|
acetoacetyl-CoA synthetase
|
-2.07935
|
|
NAT10
|
N-acetyltransferase 10 (GCN5-related)
|
-2.01685
|
