CRCGN015_MCF10A.TP53.M_24H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caffeic-acid 32.81 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

464 genes differentially expressed following the CRCGN015_MCF10A.TP53.M_24H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SCRN1 secernin 1 5.41515
TARBP1 TAR (HIV-1) RNA binding protein 1 5.40845
NUP133 nucleoporin 133kDa 5.1115
AKT1 v-akt murine thymoma viral oncogene homolog 1 4.9529
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.847
E2F2 E2F transcription factor 2 4.8312
WFS1 Wolfram syndrome 1 (wolframin) 4.8233
VGLL4 vestigial-like family member 4 4.694
FKBP14 FK506 binding protein 14, 22 kDa 4.62315
CIAO3 cytosolic iron-sulfur assembly component 3 4.5675
LGMN legumain 4.438
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 4.31237
PCDHA10 protocadherin alpha 10 3.9299
HLA-DRA major histocompatibility complex, class II, DR alpha 3.80398
IGFBP3 insulin-like growth factor binding protein 3 3.8009
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 3.72865
USP39 ubiquitin specific peptidase 39 3.62215
POU4F1 POU class 4 homeobox 1 3.56145
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 3.4792
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 3.41528
MATK megakaryocyte-associated tyrosine kinase 3.39605
PODXL2 podocalyxin-like 2 3.3321
PLEKHJ1 pleckstrin homology domain containing, family J member 1 3.223
MORN1 MORN repeat containing 1 3.20095
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 3.17015
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.16965
ATP9B ATPase, class II, type 9B 3.16393
PARD6A par-6 family cell polarity regulator alpha 3.15345
PHF13 PHD finger protein 13 3.1083
CCDC91 coiled-coil domain containing 91 3.1008
PRKCG protein kinase C, gamma 3.0966
DUX4 double homeobox 4 3.0947
DTX2 deltex 2, E3 ubiquitin ligase 3.07975
INPP5J inositol polyphosphate-5-phosphatase J 3.06795
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 3.048
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 3.0259
HBA1 hemoglobin, alpha 1 2.99879
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.998
MXD3 MAX dimerization protein 3 2.9966
CLCN7 chloride channel, voltage-sensitive 7 2.98897
PGLYRP1 peptidoglycan recognition protein 1 2.9594
IPO8 importin 8 2.95485
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.94253
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.9283
MACROH2A2 macroH2A.2 histone 2.91715
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.9077
TRIM9 tripartite motif containing 9 2.90695
PRSS22 protease, serine, 22 2.90045
GFI1 growth factor independent 1 transcription repressor 2.89025
BMP3 bone morphogenetic protein 3 2.88955
LYRM9 LYR motif containing 9 2.8813
OSGEP O-sialoglycoprotein endopeptidase 2.86955
PITX3 paired-like homeodomain 3 2.8583
EXTL1 exostosin-like glycosyltransferase 1 2.8396
POMC proopiomelanocortin 2.8356
TERF2 telomeric repeat binding factor 2 2.83395
CFAP410 cilia and flagella associated protein 410 2.82348
ATG7 autophagy related 7 2.8059
NKX2-8 NK2 homeobox 8 2.79965
KLK15 kallikrein-related peptidase 15 2.79835
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.7946
CBARP CACN subunit beta associated regulatory protein 2.77435
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.7542
MXRA8 matrix-remodelling associated 8 2.753
GPR162 G protein-coupled receptor 162 2.7467
GJA3 gap junction protein, alpha 3, 46kDa 2.74545
WNT4 wingless-type MMTV integration site family, member 4 2.74505
ECI1 enoyl-CoA delta isomerase 1 2.72465
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.71405
LMOD1 leiomodin 1 (smooth muscle) 2.71368
RHD Rh blood group, D antigen 2.70855
E4F1 E4F transcription factor 1 2.7054
AKR1C4 aldo-keto reductase family 1, member C4 2.7018
EVX1 even-skipped homeobox 1 2.6961
SREK1IP1 SREK1-interacting protein 1 2.69445
PRDM8 PR domain containing 8 2.6921
CES1 carboxylesterase 1 2.68045
NKX2-5 NK2 homeobox 5 2.67605
COPS6 COP9 signalosome subunit 6 2.67125
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.669
OLIG2 oligodendrocyte lineage transcription factor 2 2.66587
ADGRB1 adhesion G protein-coupled receptor B1 2.6529
GRK1 G protein-coupled receptor kinase 1 2.6501
TF transferrin 2.64988
S1PR4 sphingosine-1-phosphate receptor 4 2.6396
ZSCAN2 zinc finger and SCAN domain containing 2 2.6322
HOXA6 homeobox A6 2.6285
CENPE centromere protein E, 312kDa 2.6197
A4GALT alpha 1,4-galactosyltransferase 2.61835
IGHMBP2 immunoglobulin mu binding protein 2 2.6176
SNAI1 snail family zinc finger 1 2.61575
TTPA tocopherol (alpha) transfer protein 2.61
RBP3 retinol binding protein 3, interstitial 2.60995
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 2.60645
GRM2 glutamate receptor, metabotropic 2 2.60525
ZNF205 zinc finger protein 205 2.5882
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.58455
TTLL3 tubulin tyrosine ligase-like family member 3 2.5806
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 2.58025
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.5795
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.5755
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 2.56798
PICK1 protein interacting with PRKCA 1 2.5671
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 2.5597
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.55455
SSTR1 somatostatin receptor 1 2.54695
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.5422
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.54025
SCRG1 stimulator of chondrogenesis 1 2.53855
GSAP gamma-secretase activating protein 2.53657
VPREB3 pre-B lymphocyte 3 2.5309
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.5297
MATN4 matrilin 4 2.5287
PRDM5 PR domain containing 5 2.52475
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.52375
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 2.52085
LBP lipopolysaccharide binding protein 2.50848
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 2.5069
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.50415
VRTN vertebrae development associated 2.4992
GBX1 gastrulation brain homeobox 1 2.48355
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.4681
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 2.4618
RAB28 RAB28, member RAS oncogene family 2.46007
LHB luteinizing hormone beta polypeptide 2.4466
GJC2 gap junction protein, gamma 2, 47kDa 2.44575
HSF4 heat shock transcription factor 4 2.44495
LOC102724594 splicing factor U2AF 35 kDa subunit 2.43595
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.43525
TMEM50B transmembrane protein 50B 2.4331
PGP phosphoglycolate phosphatase 2.4314
STX10 syntaxin 10 2.4314
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.43105
PRDM13 PR domain containing 13 2.4301
GPR27 G protein-coupled receptor 27 2.42785
HMX1 H6 family homeobox 1 2.4226
RAX retina and anterior neural fold homeobox 2.4142
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.41015
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.40945
KIAA1614 KIAA1614 2.4075
SAGE1 sarcoma antigen 1 2.4065
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.40571
FABP4 fatty acid binding protein 4, adipocyte 2.3978
DEFA4 defensin, alpha 4, corticostatin 2.3946
LUC7L LUC7-like (S. cerevisiae) 2.3946
CFHR2 complement factor H-related 2 2.39385
ACOX3 acyl-CoA oxidase 3, pristanoyl 2.3843
GUF1 GUF1 GTPase homolog (S. cerevisiae) 2.3818
BAIAP3 BAI1-associated protein 3 2.38115
CIRSR corepressor of RBPJ and splicing regulator 2.37995
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 2.3738
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.37235
EMILIN1 elastin microfibril interfacer 1 2.37175
DOCK3 dedicator of cytokinesis 3 2.3716
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.36335
FOXI1 forkhead box I1 2.3617
MFAP4 microfibrillar-associated protein 4 2.35745
LRP1B low density lipoprotein receptor-related protein 1B 2.3466
PTPRS protein tyrosine phosphatase, receptor type, S 2.3457
CEND1 cell cycle exit and neuronal differentiation 1 2.3456
TMEM101 transmembrane protein 101 2.3443
PNMA3 paraneoplastic Ma antigen 3 2.3432
FAM110A family with sequence similarity 110, member A 2.3391
SYK spleen tyrosine kinase 2.3373
BCAP29 B-cell receptor-associated protein 29 2.3314
CEP72 centrosomal protein 72kDa 2.3276
PKD2L1 polycystic kidney disease 2-like 1 2.3265
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.32375
GTF2IRD2B GTF2I repeat domain containing 2B 2.32365
AGO4 argonaute RISC catalytic component 4 2.3233
ZMAT5 zinc finger, matrin-type 5 2.32285
DEPDC5 DEP domain containing 5 2.3202
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.31995
HOXD13 homeobox D13 2.31178
SKA1 spindle and kinetochore associated complex subunit 1 2.3081
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.30805
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.3061
THADA thyroid adenoma associated 2.30355
CFAP69 cilia and flagella associated protein 69 2.2969
YJU2B YJU2 splicing factor homolog B 2.29585
UBE2I ubiquitin-conjugating enzyme E2I 2.29432
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.29385
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.291
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.29075
TPRA1 transmembrane protein, adipocyte asscociated 1 2.28625
MEAK7 MTOR associated protein, eak-7 homolog 2.28555
RFX2 regulatory factor X, 2 (influences HLA class II expression) 2.28425
EPCIP exosomal polycystin 1 interacting protein 2.2821
AMH anti-Mullerian hormone 2.28185
CBY1 chibby homolog 1 (Drosophila) 2.28145
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 2.28067
ABI3BP ABI family, member 3 (NESH) binding protein 2.2796
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.27738
F13B coagulation factor XIII, B polypeptide 2.27645
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.2748
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.27445
PARP11 poly (ADP-ribose) polymerase family, member 11 2.273
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.26875
BLMH bleomycin hydrolase 2.2667
JPH2 junctophilin 2 2.2648
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 2.26395
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 2.259
TXLNG taxilin gamma 2.25655
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.25438
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.25355
GDF2 growth differentiation factor 2 2.25055
NKG7 natural killer cell granule protein 7 2.25005
ADRA2B adrenoceptor alpha 2B 2.2469
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.24465
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.24465
KLHDC4 kelch domain containing 4 2.24385
FOXB1 forkhead box B1 2.2418
SLC68A1 solute carrier family 68 member 1 2.24175
ERN1 endoplasmic reticulum to nucleus signaling 1 2.24065
NUP42 nucleoporin 42 2.23855
RANBP3 RAN binding protein 3 2.23116
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.23047
SCRN3 secernin 3 2.22685
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 2.22335
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.22295
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 2.22015
EPHA7 EPH receptor A7 2.2196
GHSR growth hormone secretagogue receptor 2.2178
ANGPTL3 angiopoietin-like 3 2.2174
NPY4R2 neuropeptide Y receptor Y4-2 2.21215
FBXO31 F-box protein 31 2.21135
LALBA lactalbumin, alpha- 2.20905
TUT7 terminal uridylyl transferase 7 2.2084
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 2.2037
EFNB1 ephrin-B1 2.2013
GH1 growth hormone 1 2.20028
VWA7 von Willebrand factor A domain containing 7 2.199
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 2.1983
HDAC11 histone deacetylase 11 2.19625
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.1948
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.1942
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.19345
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.19315
HDAC6 histone deacetylase 6 2.19012
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.1897
CTBP2 C-terminal binding protein 2 2.1892
NTSR1 neurotensin receptor 1 (high affinity) 2.1879
ZNF343 zinc finger protein 343 2.1865
CATSPERH catsper channel auxiliary subunit eta 2.1828
SART1 squamous cell carcinoma antigen recognized by T cells 2.18255
VWA5A von Willebrand factor A domain containing 5A 2.18107
FAT2 FAT atypical cadherin 2 2.1791
PDGFRL platelet-derived growth factor receptor-like 2.17545
ASCC1 activating signal cointegrator 1 complex subunit 1 2.1728
NEUROG3 neurogenin 3 2.16945
KCTD15 potassium channel tetramerization domain containing 15 2.16755
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 2.1673
AFF3 AF4/FMR2 family, member 3 2.1662
HOXA3 homeobox A3 2.1659
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.1641
NINJ1 ninjurin 1 2.1639
CARD8 caspase recruitment domain family, member 8 2.16315
SCMH1 sex comb on midleg homolog 1 (Drosophila) 2.16305
ERN2 endoplasmic reticulum to nucleus signaling 2 2.1623
LRRC37A3 leucine rich repeat containing 37, member A3 2.1596
ARID5A AT rich interactive domain 5A (MRF1-like) 2.15815
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.15675
TRAPPC13 trafficking protein particle complex 13 2.1563
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 2.15503
TMEM156 transmembrane protein 156 2.1511
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.14995
ABHD8 abhydrolase domain containing 8 2.1453
DPT dermatopontin 2.14307
ZNF711 zinc finger protein 711 2.14245
S1PR5 sphingosine-1-phosphate receptor 5 2.1413
COPZ2 coatomer protein complex, subunit zeta 2 2.14065
RAB40C RAB40C, member RAS oncogene family 2.13805
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 2.13755
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.1374
ZNF516 zinc finger protein 516 2.13725
FPGT fucose-1-phosphate guanylyltransferase 2.1292
NEURL1 neuralized E3 ubiquitin protein ligase 1 2.12823
SETD1B SET domain containing 1B 2.12775
BICDL1 BICD family like cargo adaptor 1 2.1257
FOXP3 forkhead box P3 2.12477
CCN5 cellular communication network factor 5 2.1238
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 2.1234
COL5A2 collagen, type V, alpha 2 2.12258
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 2.119
ELAC1 elaC ribonuclease Z 1 2.11515
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.1071
TCAP titin-cap 2.1042
REEP2 receptor accessory protein 2 2.1039
B3GAT1 beta-1,3-glucuronyltransferase 1 2.1034
GTPBP8 GTP-binding protein 8 (putative) 2.1029
THOP1 thimet oligopeptidase 1 2.10255
GLP2R glucagon-like peptide 2 receptor 2.102
EXTL3 exostosin-like glycosyltransferase 3 2.1016
FGF8 fibroblast growth factor 8 (androgen-induced) 2.10105
SNX4 sorting nexin 4 2.09985
DEFA3 defensin, alpha 3, neutrophil-specific 2.0973
EMC10 ER membrane protein complex subunit 10 2.09535
PTDSS2 phosphatidylserine synthase 2 2.09145
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.0901
NDOR1 NADPH dependent diflavin oxidoreductase 1 2.08895
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.0887
MEGF8 multiple EGF-like-domains 8 2.0875
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 2.08623
HPR haptoglobin-related protein 2.0834
LMF1 lipase maturation factor 1 2.08087
PDCD1 programmed cell death 1 2.0806
DOT1L DOT1-like histone H3K79 methyltransferase 2.07975
SIGLEC8 sialic acid binding Ig-like lectin 8 2.07918
RFX1 regulatory factor X, 1 (influences HLA class II expression) 2.0783
MED27 mediator complex subunit 27 2.07638
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.07585
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.07575
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 2.07562
CHRDL1 chordin-like 1 2.0747
IL12RB2 interleukin 12 receptor, beta 2 2.07285
DKKL1 dickkopf-like 1 2.06815
NUP62CL nucleoporin 62kDa C-terminal like 2.0675
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.06705
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.06643
CBFB core-binding factor, beta subunit 2.0661
CDO1 cysteine dioxygenase type 1 2.06065
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.0587
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 2.05772
SPX spexin hormone 2.05705
UBTD1 ubiquitin domain containing 1 2.05675
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.05645
CNTN6 contactin 6 2.05605
TELO2 telomere maintenance 2 2.05533
GTPBP1 GTP binding protein 1 2.05512
BAALC brain and acute leukemia, cytoplasmic 2.0533
LIMS2 LIM and senescent cell antigen-like domains 2 2.05305
TP53 tumor protein p53 2.0483
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.04485
SDK2 sidekick cell adhesion molecule 2 2.0442
BCL2 B-cell CLL/lymphoma 2 2.04383
DNAH9 dynein, axonemal, heavy chain 9 2.0426
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.0402
DGKQ diacylglycerol kinase, theta 110kDa 2.03865
SLC30A9 solute carrier family 30 (zinc transporter), member 9 2.03705
TMEM121 transmembrane protein 121 2.03685
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 2.03665
GSTM5 glutathione S-transferase mu 5 2.03235
LRRC3 leucine rich repeat containing 3 2.0315
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.0314
DNTT DNA nucleotidylexotransferase 2.031
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.0299
GP9 glycoprotein IX (platelet) 2.02925
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2.0289
TXNRD3 thioredoxin reductase 3 2.02868
SIL1 SIL1 nucleotide exchange factor 2.02865
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.02775
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.02682
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.02595
SOX11 SRY (sex determining region Y)-box 11 2.0253
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.02355
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.02345
NBEAL2 neurobeachin-like 2 2.02195
NMUR1 neuromedin U receptor 1 2.0215
KANK2 KN motif and ankyrin repeat domains 2 2.02032
FASLG Fas ligand (TNF superfamily, member 6) 2.02017
VRK2 vaccinia related kinase 2 2.01245
CELF3 CUGBP, Elav-like family member 3 2.0095
FOXC2 forkhead box C2 2.0077
AMN amnion associated transmembrane protein 2.00745
GHRHR growth hormone releasing hormone receptor 2.00727
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.00705
NABP1 nucleic acid binding protein 1 2.0049
IQCB1 IQ motif containing B1 2.00483
DMAC2L distal membrane arm assembly component 2 like 2.00257
MYBPC3 myosin binding protein C, cardiac 2.0015
CNGA3 cyclic nucleotide gated channel alpha 3 2.0007

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.61275
HSPA8 heat shock 70kDa protein 8 -5.31847
FASTKD5 FAST kinase domains 5 -5.1475
CDC45 cell division cycle 45 -4.65445
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.1387
KDM3A lysine (K)-specific demethylase 3A -4.1161
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.92975
TIMP1 TIMP metallopeptidase inhibitor 1 -3.7412
GRN granulin -3.65863
PMM2 phosphomannomutase 2 -3.6378
SMG8 SMG8 nonsense mediated mRNA decay factor -3.63415
FOS FBJ murine osteosarcoma viral oncogene homolog -3.6158
C1QBP complement component 1, q subcomponent binding protein -3.5458
SF3B4 splicing factor 3b, subunit 4, 49kDa -3.5097
DCK deoxycytidine kinase -3.4463
TUBA4A tubulin, alpha 4a -3.3747
SNRPE small nuclear ribonucleoprotein polypeptide E -3.2337
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -3.21875
TBC1D10B TBC1 domain family, member 10B -3.0074
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.96633
THOC7 THO complex 7 -2.9152
NTAQ1 N-terminal glutamine amidase 1 -2.89425
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.88583
CCDC51 coiled-coil domain containing 51 -2.83995
DTD1 D-tyrosyl-tRNA deacylase 1 -2.83915
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.76027
QPRT quinolinate phosphoribosyltransferase -2.75595
CD320 CD320 molecule -2.7202
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -2.6919
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.68775
GPATCH2 G patch domain containing 2 -2.657
TEX264 testis expressed 264 -2.63265
SEC61G Sec61 gamma subunit -2.6189
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.60095
MTIF2 mitochondrial translational initiation factor 2 -2.57115
SOCS1 suppressor of cytokine signaling 1 -2.5403
POPDC3 popeye domain containing 3 -2.53535
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.5106
PDCD6IP programmed cell death 6 interacting protein -2.50885
ACTMAP actin maturation protease -2.50675
SLIRP SRA stem-loop interacting RNA binding protein -2.4885
RNF139 ring finger protein 139 -2.45435
EPS8 epidermal growth factor receptor pathway substrate 8 -2.452
ESYT1 extended synaptotagmin-like protein 1 -2.44335
RPA3 replication protein A3, 14kDa -2.43415
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.36175
CDKN3 cyclin-dependent kinase inhibitor 3 -2.3612
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.3578
RBM7 RNA binding motif protein 7 -2.35415
MCTS1 malignant T cell amplified sequence 1 -2.3503
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.34755
DUSP10 dual specificity phosphatase 10 -2.33475
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -2.3297
COXFA4 cytochrome c oxidase associated subunit FA4 -2.32545
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.3198
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.3174
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -2.31695
NOL11 nucleolar protein 11 -2.3053
GLRX2 glutaredoxin 2 -2.3053
DENND4B DENN/MADD domain containing 4B -2.29875
MTX2 metaxin 2 -2.2906
SLC67A1 solute carrier family 67 member 1 -2.2885
EIF3D eukaryotic translation initiation factor 3, subunit D -2.27865
TMEM94 transmembrane protein 94 -2.20965
TYRP1 tyrosinase-related protein 1 -2.1828
MAIP1 matrix AAA peptidase interacting protein 1 -2.1822
CR2 complement component (3d/Epstein Barr virus) receptor 2 -2.18125
TMEM14A transmembrane protein 14A -2.1635
XPO1 exportin 1 -2.1616
MOAP1 modulator of apoptosis 1 -2.1569
ACAA1 acetyl-CoA acyltransferase 1 -2.15277
AHR aryl hydrocarbon receptor -2.14625
PDGFC platelet derived growth factor C -2.13125
PLK2 polo-like kinase 2 -2.1271
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.11265
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -2.1055
ATP5F1E ATP synthase F1 subunit epsilon -2.1047
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.09125
COX7C cytochrome c oxidase subunit VIIc -2.09105
RPS5 ribosomal protein S5 -2.08095
ZWINT ZW10 interacting kinetochore protein -2.0766
TMX1 thioredoxin-related transmembrane protein 1 -2.0661
VMP1 vacuole membrane protein 1 -2.06165
TMEM14B transmembrane protein 14B -2.05655
NGRN neugrin, neurite outgrowth associated -2.0448
CTSV cathepsin V -2.0439
MCM3 minichromosome maintenance complex component 3 -2.02125
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.01725
ADIPOR1 adiponectin receptor 1 -2.0124
TFB2M transcription factor B2, mitochondrial -2.01
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0091
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.00475
ATP5PD ATP synthase peripheral stalk subunit d -2.0047